Results 91 to 100 of about 16,807 (206)
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.African swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Jie Chen +13 more
wiley +1 more source
Frontiers in Veterinary Science, 2021 Porcine reproductive and respiratory syndrome virus (PRRSV) causes a highly contagious disease and brings huge economic losses to commercial pork production worldwide.
Baishuang Yin +8 more
semanticscholar +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li +8 more
wiley +1 more source
MicroRNA 181 Suppresses Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection by Targeting PRRSV Receptor CD163 [PDF]
Journal of Virology, 2013 ABSTRACTWe previously showed that microRNA 181 (miR-181) can inhibit PRRSV replication by directly targeting its genomic RNA. Here, we report that miR-181 can downregulate the PRRSV receptor CD163 in blood monocytes and porcine alveolar macrophages (PAMs) through targeting the 3′ untranslated region (UTR) of CD163 mRNA. Downregulation of CD163 leads to
Li, Gao +7 more
openaire +2 more sources
Vaccines, 2023 Commercially used porcine respiratory and reproductive syndrome (PRRS) modified live virus (MLV) vaccines provide limited protection with heterologous viruses, can revert back to a virulent form and they tend to recombine with circulating wild-type strains.
Min-A Lee +9 more
openaire +3 more sources
PLoS ONE, 2021 Porcine reproductive and respiratory syndrome virus genotype 2 (PRRSV-2) genetic diversity in the U.S. was assessed using a database comprising 10 years’ worth of sequence data obtained from swine production systems routine monitoring and outbreak ...
M. Kikuti +5 more
semanticscholar +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease indistinguishable from foot‐and‐mouth disease virus (FMDV). So far, there are no commercial vaccines and effective therapeutic drugs against SVA infection in China. Here, a library of 112 compounds were screened, and we found that phorbol myristate acetate plays an antagonistic ...
Junfang Yan +6 more
wiley +1 more source
Scientific Reports, 2021 Two distinct experiments (Exp) were conducted to evaluate the shedding and efficacy of 2 modified live porcine reproductive and respiratory syndrome virus (PRRSV) type 2 vaccines (MLV) when administered intramuscularly (IM) or intradermally (ID) (Exp A),
A. Madapong +3 more
semanticscholar +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Yan Gong +10 more
wiley +1 more source
Vaccines, 2023 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) remains an infectious agent with high importance in the swine industry. In this study, the influence of maternally derived antibodies (MDAs) on an experimental PRRSV-1 challenge is investigated. Piglets included in the study (n = 36) originated from a Belgian farrow-to-finish herd in which the
Fiers, Jorian +7 more
openaire +4 more sources