Results 51 to 60 of about 16,807 (206)

Effects of high molecular weight poly-γ-glutamic acid on PIGS with porcine preproductive and respiratory syndrome virus (PRRSV) infection

Acta Veterinaria, 2017
Bacillus subtilis sups. chungkookjang produces a higher molecular mass poly-γ-glutamic acid (γ-PGA). Recently, previous studies have demonstrated immune stimulation and an antitumor effect of the high molecular mass γ-PGA using various mouse models ...
Seo Byoung-Joo, Lee Jee-Hoon, Kang Ick-Jae, Shabir Nadeem, Khatun Amina, Yang Myeon-Sik, Park Chul, Kim Bumseok, Kim Won-Il   +8 more
doaj   +1 more source

Characterizing the PRRSV nsp2 Deubiquitinase Reveals Dispensability of Cis-Activity for Replication and a Link of nsp2 to Inflammation Induction

Viruses, 2019
The papain-like cysteine protease 2 (PLP2) within the N-terminus of the porcine reproductive and respiratory syndrome virus (PRRSV) nsp2 replicase protein specifies a deubiquitinating enzyme (DUB), but its biochemical properties and the role in infection
Shaochuan Zhou, Xinna Ge, Can Kong, Teng Liu, Aijing Liu, Peng Gao, Jiangwei Song, Lei Zhou, Xin Guo, Jun Han, Hanchun Yang   +10 more
doaj   +1 more source

Risk Factors and Spatial-Temporal Analysis of Porcine Reproductive and Respiratory Syndrome Seroprevalence in China Before and After African Swine Fever Outbreak

Frontiers in Veterinary Science, 2022
Porcine reproductive and respiratory syndrome (PRRS) is an infectious viral disease that causes great harm to the pig industry. PRRS virus (PRRSV), the causative agent of PRRS, is characterized by severe reproductive failure and respiratory confusion ...
Pengfei Zhao, Chaofei Wang, Wenjian Cao, Rui Fang, Junlong Zhao   +4 more
doaj   +1 more source

The Function of the PRRSV–Host Interactions and Their Effects on Viral Replication and Propagation in Antiviral Strategies

Vaccines, 2021
Porcine reproductive and respiratory syndrome virus (PRRSV) affects the global swine industry and causes disastrous economic losses each year. The genome of PRRSV is an enveloped single-stranded positive-sense RNA of approximately 15 kb.
Jun Ma, Lulu Ma, Meiting Yang, Wei Wu, W. Feng, Zhongzhou Chen   +5 more
semanticscholar   +1 more source

Highly Pathogenic PRRSV-Infected Alveolar Macrophages Impair the Function of Pulmonary Microvascular Endothelial Cells

Viruses, 2022
The porcine reproductive and respiratory syndrome virus (PRRSV), especially the highly pathogenic strains, can cause serious acute lung injury (ALI), characterized by extensive hemorrhage, inflammatory cells and serous fluid infiltration in the lung ...
Weifeng Sun, Weixin Wu, N. Jiang, X. Ge, Yongning Zhang, Jun Han, Xin Guo, Lei Zhou, Hanchun Yang   +8 more
semanticscholar   +1 more source

Activating Fc Gamma Receptors and Viral Receptors Are Required for Antibody-Dependent Enhancement of Porcine Reproductive and Respiratory Syndrome Virus Infection

Veterinary Sciences, 2022
Antibody-dependent enhancement (ADE) is an event in preexisting sub-, or non-neutralizing antibodies increasing the viral replication in its target cells.
Liujun Zhang, Huandi Wang, Wen Li, Xing Feng, Fangfang Han, Yina Zhang, Jing Chen, Deyi Liu, Pingan Xia   +8 more
doaj   +1 more source

Restriction fragment length polymorphism of ORF6 and ORF7 genes of porcine reproductive and respiratory syndrome virus (PRRSV) vaccine strains registered in the Czech Republic

Veterinární Medicína, 2006
Restriction fragment length polymorphism (RFLP) of open reading frames 6 and 7 was applied to comparative genetic analysis of live attenuated vaccine strains (Amervac-PRRS/A3, Porcilis PRRS, Ingelvac PRRS) of porcine reproductive and respiratory syndrome
E. Kosinova, I. Psikal
doaj   +1 more source

A Novel Motif in the 3′-UTR of PRRSV-2 Is Critical for Viral Multiplication and Contributes to Enhanced Replication Ability of Highly Pathogenic or L1 PRRSV

Viruses, 2022
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) with enhanced replication capability emerged in China and has become dominant epidemic strain since 2006.
Junyao Xiong, Xingyang Cui, Kuan Zhao, Qian Wang, Xinyi Huang, Dongyan Li, Fang Yu, Yongbo Yang, Di Liu, Zhijun Tian, Xuehui Cai, Tongqing An   +11 more
doaj   +1 more source

CD163-Expressing Porcine Macrophages Support NADC30-like and NADC34-like PRRSV Infections

Viruses, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) has a strict cell tropism. In addition to the primary alveolar macrophages, PRRSV is strictly cytotropic to African green monkey kidney cells, such as MARC-145 cells; however, MARC-145 cells are
Yulin Xu, M. Ye, Shaohua Sun, Qishu Cao, Jia Luo, Yuening Wang, Wanglong Zheng, F. Meurens, Nanhua Chen, Jianzhong Zhu   +9 more
semanticscholar   +1 more source

The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function

Viruses, 2021
Porcine reproductive and respiratory syndrome virus (PRRSV) modulates host innate immunity which plays a key role against PRRSV infection. As a RNA virus, PRRSV is mainly sensed by innate immune RNA receptors, whereas the role of innate immune DNA ...
Yulin Xu, Youwen Zhang, Shaohua Sun, Jia Luo, Sen Jiang, Jiajia Zhang, Xueliang Liu, Qi Shao, Qi Cao, Wanglong Zheng, Nanhua Chen, François Meurens, Jianzhong Zhu   +12 more
doaj   +1 more source