Results 111 to 120 of about 3,801 (180)

Additional file 2 of PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis

Additional file 2: Table S2. The sequences of primers utilized for qRT-PCR.
Jia, Linglu, Li, Dongfang, Wang, Ya-Nan, Zhang, Dongjiao, Xu, Xin   +4 more
openaire   +1 more source

Additional file 5 of PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis

Additional file 5: Figure S2. The interference efficiency of using siRNA to interfere with target genes in PDLSCs.
Jia, Linglu, Li, Dongfang, Wang, Ya-Nan, Zhang, Dongjiao, Xu, Xin   +4 more
openaire   +1 more source

Identification and Validation of Serum Biomarkers to Improve Colorectal Cancer Diagnosis

Cancer Medicine
Background The pressing need for reliable biomarkers in colorectal cancer (CRC) diagnosis and prognosis is a major global health concern. Current diagnostic methods rely heavily on invasive procedures like colonoscopy, and existing biomarkers such as ...
Minha Lea Yoon, Hyelim Chun, HyunJu Lee, WooJeong Seo, Jung Young Lee, Jung Hwan Yoon   +5 more
doaj   +1 more source

PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway

Journal of Cancer
Background: The metastasis of colorectal cancer (CRC) is one of the significant barriers impeding its treated consequence and bring about high mortality, less surgical resection rate and poor prognosis of CRC patients. PSAT1 is an enzyme involved in serine biosynthesis.
Wang, Mingjin, Zhang, Houshun, Lu, Zhiyuan, Su, Wenrui, Tan, Yanan, Wang, Jiayu, Jia, Xiaoyi   +6 more
openaire   +2 more sources

Phosphoserine aminotransferase1의 구조적 특성을 기반으로 한 저해제 발굴 [PDF]

, 2017
학위논문 (석사)-- 서울대학교 대학원 : 융합과학기술대학원 분자의학 및 바이오제약 전공, 2017. 2. 윤홍덕.Phosphoserine aminotransferase 1 (Psat1) is a transaminase involved in de novo serine biosynthesis pathway generating α-ketoglutarate (α-KG) (Baek et al., 2003).
Kim Young Ah
core  

CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon

JCI Insight
Patients with cholangiocarcinoma have poor clinical outcomes due to late diagnoses, poor prognoses, and limited treatment strategies. To identify drug combinations for this disease, we have conducted a genome-wide CRISPR screen anchored on the ...
Yan Zhu, Dengyong Zhang, Pooja Shukla, Young-Ho Jung, Prit Benny Malgulwar, Sharmeen Chagani, Medina Colic, Sarah Benjamin, John A. Copland III, Lin Tan, Philip L. Lorenzi, Milind Javle, Jason T. Huse, Jason Roszik, Traver Hart, Lawrence N. Kwong   +15 more
doaj   +1 more source

Integrative Bulk and Single-Cell Transcriptome Profiling of Telomere-Related Genes Reveals a Robust Prognostic Signature and Immunotherapeutic Landscape in Neuroblastoma. [PDF]

J Cancer
Aierken Y, Zheng L, Liu T, Tan K, Lv Z.
europepmc   +1 more source

A Three-Gene Prognostic Signature Driven by an ER Stress-Associated ceRNA Network: Integrating Single-Cell Transcriptomics and Cross-Platform Validation in Hepatocellular Carcinoma. [PDF]

Curr Issues Mol Biol
Shi Q, Gao S, Chen B, Shen M, Han J.
europepmc   +1 more source

SNHG12 drives gastric cancer progression by activating the Wnt/β-catenin-mediated serine synthesis pathway. [PDF]

J Transl Med
Zhang N, Li T, Wen K.
europepmc   +1 more source

A multi-omics prognostic model and functional validation of <i>HPGD</i> in clear cell renal cell carcinoma. [PDF]

Transl Androl Urol
Du Y, Zheng Y, Zhang X, Wang H, Zhang H, Shang P.   +5 more
europepmc   +1 more source