Results 121 to 130 of about 3,665 (185)

CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon

JCI Insight
Patients with cholangiocarcinoma have poor clinical outcomes due to late diagnoses, poor prognoses, and limited treatment strategies. To identify drug combinations for this disease, we have conducted a genome-wide CRISPR screen anchored on the ...
Yan Zhu, Dengyong Zhang, Pooja Shukla, Young-Ho Jung, Prit Benny Malgulwar, Sharmeen Chagani, Medina Colic, Sarah Benjamin, John A. Copland III, Lin Tan, Philip L. Lorenzi, Milind Javle, Jason T. Huse, Jason Roszik, Traver Hart, Lawrence N. Kwong   +15 more
doaj   +1 more source

Additional file 1 of PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis

Additional file 1: Table S1. The sequences of siRNAs.
Jia, Linglu, Li, Dongfang, Wang, Ya-Nan, Zhang, Dongjiao, Xu, Xin   +4 more
openaire   +1 more source

Integrative Bulk and Single-Cell Transcriptome Profiling of Telomere-Related Genes Reveals a Robust Prognostic Signature and Immunotherapeutic Landscape in Neuroblastoma. [PDF]

J Cancer
Aierken Y, Zheng L, Liu T, Tan K, Lv Z.
europepmc   +1 more source

SNHG12 drives gastric cancer progression by activating the Wnt/β-catenin-mediated serine synthesis pathway. [PDF]

J Transl Med
Zhang N, Li T, Wen K.
europepmc   +1 more source

A multi-omics prognostic model and functional validation of <i>HPGD</i> in clear cell renal cell carcinoma. [PDF]

Transl Androl Urol
Du Y, Zheng Y, Zhang X, Wang H, Zhang H, Shang P.   +5 more
europepmc   +1 more source

The "serine code" of metabolic reprogramming: multidimensional roles of the serine synthesis pathway in tumors and novel breakthroughs for targeted therapy. [PDF]

Front Immunol
Su P, Yang Y, Zheng H.
europepmc   +1 more source

The effect of phosphoserine aminotransferase-1 dependent fluctuation on timing of embryonic stem cell differentiation

, 2016
학위논문 (박사)-- 서울대학교 대학원 : 의과학과, 2016. 8. 윤홍덕.Embryonic stem cells (ESCs) undergo coordinated epigenetic and metabolic changes to differentiate properly.
황인영
core  

Metabolic remodeling and immune evasion in glioblastoma: a focus on serine and lipid networks. [PDF]

Front Oncol
Jiang D, Wang C, Zhao Y, Li Y.
europepmc   +1 more source

Association between SQSTM1 dysregulation and risk in alopecia areata: a Mendelian randomization study. [PDF]

Front Immunol
Hu L, Wan S, Song X.
europepmc   +1 more source

Serine metabolism reprogramming in cancer: a multi-tiered regulatory framework. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Yuan Y, Wang K, Jin Y, Han T.
europepmc   +1 more source