Results 151 to 160 of about 3,665 (185)

Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas. [PDF]

open access: yesNat Commun
Aussel A   +15 more
europepmc   +1 more source

LMTK3 regulation of EV biogenesis and cargo sorting promotes tumour growth by reducing monocyte infiltration and driving pro-tumourigenic macrophage polarisation in breast cancer. [PDF]

open access: yesMol Cancer
Samuels M   +11 more
europepmc   +1 more source

Epigenetic regulation of serine biosynthesis by PHF8 during neurogenesis. [PDF]

open access: yesEMBO Rep
Artes MH   +16 more
europepmc   +1 more source

The inhibitory receptor LAG3 affects NK cell IFN-γ production through glycolysis and the PSAT1/STAT1/IFNG pathway. [PDF]

open access: yesmBio
Ge H   +13 more
europepmc   +1 more source

De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma. [PDF]

open access: yesCancer Res
Teisseire M   +12 more
europepmc   +1 more source

Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors

open access: yesCell Reports, 2022
A major challenge of targeting metabolism for cancer therapy is pathway redundancy, in which multiple sources of critical nutrients can limit the effectiveness of some metabolism-targeted therapies.
Vipin Rawat   +2 more
exaly   +3 more sources

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