Results 91 to 100 of about 14,046 (214)

Genomic Analysis and Virulence Features of Vibrio cholerae Non‐O1/Non‐O139 Harbouring CARB‐Type β‐Lactamases From Freshwater Bodies, Argentina

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Genomic analysis of ampicillin‐resistant Vibrio cholerae non‐O1/non‐O139 from central Argentina's freshwater bodies identified four novel CARB‐β‐lactamase variants linked to the V. cholerae superintegron. An unusual VPI‐1 arrangement encoding the TCP pilus and a type VI secretion system subclass i5 was also found, associated with increased ...
Daiana Guevara Núñez   +10 more
wiley   +1 more source

Identification of a Chitin-Binding Protein Secreted by Pseudomonas aeruginosa [PDF]

open access: yes, 1999
One of the major proteins secreted by Pseudomonas aeruginosa is a 43-kDa protein, which is cleaved by elastase into smaller fragments, including a 30-kDa and a 23-kDa fragment. The N-terminal 23-kDa fragment was previously suggested as corresponding to
Bitter, Wilbert   +3 more
core   +1 more source

The Immunomodulatory Effect of Recombinant Exotoxin A of Pseudomonas Aeruginosa on Dendritic Cells Extracted from Mice Spleen

open access: yesJournal of Fasa University of Medical Sciences, 2015
Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi   +3 more
doaj  

DEVELOPMENT OF THE VACCINE BASED ON THE RECOMBINANT ANTIGENS OF PSEUDOMONAS AERUGINOSA

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. The aim is obtaining, investigation and selection of recombinant antigens for inclusion theirs into the against Pseudomonas vaccine. Materials and methods. The genes encoding of the outer  membrane proteins F, L and I and Exotoxin A were synthesized
N. A. Mihailova   +3 more
doaj   +1 more source

Cloning and expression of the immunogenic moiety of Pseudomonas aeruginosa exotoxin A

open access: yesBiological Journal of Microorganism, 2013
Introduction: Pseudomonas aeruginosa, as an opportunistic microorganism, is a major cause of nosocomial infections worldwide. Exotoxin A (ETA) is an extracellular enzyme that is produced by most clinical strains of P. aeruginosa.
Sahar Nouri Gharajelar *   +2 more
doaj  

Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.

open access: yesPLoS ONE, 2012
Homologs of the transcriptional regulator PtxS are omnipresent in Pseudomonas, whereas PtxR homologues are exclusively found in human pathogenic Pseudomonas species.
Abdelali Daddaoua   +5 more
doaj   +1 more source

A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin.

open access: yesPLoS ONE, 2010
Diphtheria toxin (DT), Pseudomonas aeruginosa Exotoxin A (ETA) and cholix toxin from Vibrio cholerae share the same mechanism of toxicity; these enzymes ADP-rybosylate elongation factor-2 (EF-2) on a modified histidine residue called diphthamide, leading
Vincent Roy, Karim Ghani, Manuel Caruso
doaj   +1 more source

Ecthyma gangrenosum caused by Pseudomonas aeruginosa in a patient with astrocytoma treated with chemotherapy [PDF]

open access: yes, 2010
Ecthyma gangrenosum, presenting as embolic lesions caused by Pseudomonas aeruginosa infection, has distinct pathognomonic features and a high mortality rate in patients with bacteremia, but when recognized early is easily treated.
Jonge, M.J.A. (Maja) de   +3 more
core   +4 more sources

Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture

open access: yesBMC Research Notes, 2019
Objective Recombinant immunotoxins (RITs) are antibody-toxin fusion proteins that can selectively eliminate populations of cells expressing specific surface receptors. They are in evaluation as therapeutic agents for cancer.
Yuyi Zhu, John E. Weldon
doaj   +1 more source

Molecular Detection of Virulence Genes among Pseudomonas aeruginosa Strains Isolated from Clinical Specimens by Multiplex PCR

open access: yesپزشکی بالینی ابن سینا, 2018
Background and Objective: Pseudomonas aeroginosa is the most common pathogen associated with nosocomial infections and possesses virulence factors which contribute to the bacterial invasion and toxicity such as alginate, exoenzyme S, exotoxin A and ...
Afsoon Shariat   +3 more
doaj  

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