Multifaceted Interplay between Hfq and the Small RNA GssA in Pseudomonas aeruginosa
Behind the pathogenic lifestyle of Pseudomonas aeruginosa exists a complex regulatory network of intertwined switches at both the transcriptional and posttranscriptional levels.
Silvia Santoro +5 more
doaj +1 more source
Aspergillus fumigatus enhances elastase production in pseudomonas aeruginosaco-cultures [PDF]
In the cystic fibrosis (CF) lung the presence of bacteria and fungi in the airways promotes an inflammatory response causing progressive lung damage, ultimately leading to high rates of morbidity and mortality.
Kerr, Stephen +6 more
core +1 more source
Enzyme-linked immunosorbent assay for Pseudomonas aeruginosa exotoxin A [PDF]
An enzyme-linked immunosorbent assay (ELISA) is described for Pseudomonas aeruginosa exotoxin A. A double antibody sandwich method was used, employing polyvinyl microtiter plates as the solid phase, a primary coat of monospecific rabbit antitoxin serum, an outer layer composed of a horseradish peroxidase-sheep antitoxin immunoglobulin G conjugate, and ...
W W, Schultz, T J, Phipps, M, Pollack
openaire +2 more sources
Toxicity of Pseudomonas aeruginosa exotoxin A for human macrophages [PDF]
Pseudomonas aeruginosa exotoxin A was toxi in vitro for human peripheral blood macrophages. Cytotoxicity, manifested by morphological evidence of cell death and inhibition of [3H]thymidine uptake, followed exposure to as little as 10 ng of exotoxin per ml for 1 h.
M, Pollack, S E, Anderson
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Candida albicans Inhibits Pseudomonas aeruginosa Virulence through Suppression of Pyochelin and Pyoverdine Biosynthesis. [PDF]
Bacterial-fungal interactions have important physiologic and medical ramifications, but the mechanisms of these interactions are poorly understood.
Coughlin, L.A. +7 more
core +3 more sources
Exotoxin A Pseudomonas aeruginosa influence on working efficiency of white rats [PDF]
Objective: to study exotoxin A Pseudomonas aeruginosa influence on physical and mental efficiency of white rats. Material and Methods. The experiments were carried out on white rats following intraperitoneal injections of exotoxin A Pseudomonas of ...
Morrison V.V. +3 more
doaj
Background: Targeted cancer therapies have played a great role in the treatment of malignant tumors, in the recent years. Among these therapies, targeted toxin therapies such as immunotoxins, has improved the patient’s survival rate by minimizing the ...
Sahel Amoozadeh +4 more
doaj +1 more source
Characterization of a cellular protease that cleaves Pseudomonas exotoxin [PDF]
Pseudomonas exotoxin (PE) is a 66-kDa bacterial toxin that is proteolytically cleaved by cells to produce an N-terminal fragment of 28 kDa and a C-terminal 37-kDa fragment which translocates to the cytosol and inhibits protein synthesis (M. Ogata, V.K. Chaudhary, I. Pastan, and D.J. FitzGerald, J. Biol. Chem. 265:20678-20685, 1990).
C, Fryling, M, Ogata, D, FitzGerald
openaire +2 more sources
The future of antiviral immunotoxins [PDF]
There is a constant need for new therapeutic interventions in a wide range of infectious diseases. Over the past few years, the immunotoxins have entered the stage as promising antiviral treatments.
Høy Jakobsen, Mette +3 more
core +1 more source
Detection of Exotoxins and Antimicrobial Susceptibility Pattern in Clinical Pseudomonas Aeruginosa Isolates [PDF]
Background: Pseudomonas aeruginosa is a common opportunistic pathogen that causes nosocomial infection in immunocompromised patients. Among different virulence factors, the type III secretion system (TTSS) is an important agent in virulence and ...
Deris, Fatemeh. +4 more
core +1 more source

