Results 61 to 70 of about 14,046 (214)

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

Advanced Healthcare Materials, Volume 15, Issue 7, 16 February 2026.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf, Hendrik Bonnemeier, Ernest W. Lau, Jana Hummel, Reinhard Vonthein, Ojan Assadian   +5 more
wiley   +1 more source

Isolation, identification, and pathogenic potential of Bacillus cereus from diseased big‐belly seahorse Hippocampus abdominalis

Journal of the World Aquaculture Society, Volume 57, Issue 1, February 2026.
Abstract Members of Bacillus cereus have been documented as important bacterial pathogens in aquaculture. However, scarce information is available on B. cereus isolates as causal pathogens of big‐belly seahorses Hippocampus abdominalis. In the present study, a B. cereus isolate (SH1), recovered from a disease outbreak on a seahorse farm, was identified
Chunlei Gai, Chenhao Teng, Yueqi Yang, Yiyao Liu, Haijing Jie, Youhong Wang, Haibin Ye, Haipeng Cao   +7 more
wiley   +1 more source

Ferric uptake regulator Fur is conditionally essential in Pseudomonas aeruginosa [PDF]

, 2017
In Pseudomonas aeruginosa, the ferric uptake regulator (Fur) protein controls both metabolism and virulence in response to iron availability. Differently from other bacteria, attempts to obtain fur deletion mutants of P. aeruginosa failed, leading to the
Banin, Ehud, Genah, Shirley, Imperi, Francesco, Lo Sciuto, Alessandra, Pasqua, Martina, Visaggio, Daniela, Visca, Paolo   +6 more
core   +1 more source

Necrotizing Pneumonia Caused by PVL‐Negative Methicillin‐Susceptible Staphylococcus aureus Complicated by Refractory Pneumothorax: A Case Report

Respirology Case Reports, Volume 14, Issue 1, January 2026.
Here we report a case of PVL‐negative MSSA necrotizing pneumonia in a previously healthy man that rapidly progressed to cavitary lesions and refractory pneumothorax. Despite its improvement after clindamycin‐based therapy, the patient experienced recurrent pneumothorax and chronic respiratory failure.
Shun Endo, Tomoka Yasuda, Makoto Izumi, Kazuhiro Shimaya, Yoshikazu Tsukada   +4 more
wiley   +1 more source

Mechanism of GSDMD in the Pathogenesis of Pasteurella multocida PmCQ2

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Pasteurella multocida serotype A (PmCQ2), a Gram‐negative zoonotic pathogen, causes severe respiratory disease in a variety of domestic and wild animals, leading to high morbidity and mortality and substantial agricultural economic losses. Pyroptosis, a gasdermin‐mediated programmed cell death mechanism, facilitates pathogen clearance but exacerbates ...
Qingqing Yang, Wei Wang, Xin Shen, Yi Lu, Jiajia Zheng, Jinrong Ran, Xuefeng Cao, Rendong Fang, Zongfu Wu   +8 more
wiley   +1 more source

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple models, secondary necrosis occurred regardless of gasdermin E presence, challenging prior claims and redefining the understanding of how apoptotic cells ...
Shubhangi Gavali, Francesca Maremonti, Wulf Tonnus, Florian Gembardt, Marlena Nastassja Schlecht, Karolin Flade, Anne von Mässenhausen, Stephen W. G. Tait, Stefan R. Bornstein, Andreas Linkermann   +9 more
wiley   +1 more source

Phenotypic and Genotypic Profile of Enterobacteriaceae Isolated at a Teaching Hospital in Ghana

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study identified a significant prevalence of antimicrobial resistance determinants within Enterobacteriaceae isolates, with particular emphasis on those producing extended‐spectrum β‐lactamases (ESBL). These isolates harbored diverse antibiotic resistance genes (ARGs), plasmid replicons, and virulence factors (VFs), highlighting the imperative for
Bismark Donkor, Richael Odarkor Mills, Philimon Mwintige, Alberta Bedford Moses, Abigail Asmah Brown, Faustina Halm‐Lai, Oheneba Charles Kofi Hagan   +6 more
wiley   +1 more source

Dissecting HOCl Action in Chronic Wound Biofilms: Proteomic Insights From a Host‐Relevant Model of Pseudomonas aeruginosa

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Impact statement: We tested a gel containing a pure, stable form of hypochlorous acid (HOCl) against P. aeruginosa. To ensure our results reflect the true effects of HOCl we used a host‐relevant biofilm model. The HOCl gel disrupted bacterial metabolism, impacted proteins associated with virulence, and changed the abundance antibiotic resistance ...
Lori I. Robins, Philip Gafken, Chenwei Lin, Lisa Jones, Sarah E. Hooper   +4 more
wiley   +1 more source

ADP-Ribosylargininyl reaction of cholix toxin is mediated through diffusible intermediates [PDF]

, 2014
Background: Cholix toxin is an ADP-ribosyltransferase found in non-O1/non-O139 strains of Vibrio cholera. The catalytic fragment of cholix toxin was characterized as a diphthamide dependent ADP-ribosyltransferase.
Sung, Vicky M-H, Tsai, Chia-Lun
core   +1 more source

Bioimaging With Fluorescent Nucleic‐Acid Aptamers for the Specific Detection and Quantification of Pseudomonas aeruginosa Alone and in Heterogeneous Bacterial Populations

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Aptamers are promising candidates for diagnostic applications due to their broad pathogen detection capability. The open‐access quantitative bioimaging software we have developed for confocal images has validated aptamer F23 as a promising tool to distinguish Pseudomonas aeruginosa from different bacterial strains. ABSTRACT Aptamers, short nucleic acid
Chaimae Mezouarhi, Romain Vauchelles, Basma Abdallah, Régine Janel, Mouna Ouadghiri, Hassan Ait Benhassou, Sandrine Pelet, Pierre Fechter, Laurence Choulier   +8 more
wiley   +1 more source