Results 71 to 80 of about 14,046 (214)

Demonstration of cell envelope-bound exotoxin A in Pseudomonas aeruginosa [PDF]

Infection and Immunity, 1980
The quantity of membrane-bound and extracellular exotoxin A in four strains of Pseudomonas aeruginosa was investigated. In strain PA-103, which is the prototype strain used for toxin production, all of the toxin was released into the growth medium and little toxin remained with the cell envelope. In a virulent strain from a clinical source, strain 119,
P B, Fernandes, K R, Cundy
openaire   +2 more sources

Active immunization using exotoxin A confers protection against Pseudomonas aeruginosa infection in a mouse burn model

BMC Microbiology, 2009
Background Pseudomonas aeruginosa is an important cause of nosocomial infection and may lead to septicemia and death. We evaluated the immunogenicity of semi-purified exotoxin A from the bacterium in a mouse burn model.
Naghmachi Mohsen, Amini Masoud, Japoni Aziz, Mehrabani Davood, Kohanteb Jamshid, Manafi Ali, Zaghi Ahmad Hosseinzadeh, Khalili Nazanin   +7 more
doaj   +1 more source

Pseudomonas exotoxin A. Membrane binding, insertion, and traversal.

Journal of Biological Chemistry, 1986
Using vesicle targets composed of phosphatidylcholine and cholesterol (1:1 molar ratio), we found that Pseudomonas aeruginosa exotoxin A (PTx) binding and insertion are not only dependent on pH (Zalman, L.S., and Wisnieski, B.J. (1985) Infect. Immun.
Z T, Farahbakhsh, R L, Baldwin, B J, Wisnieski   +2 more
openaire   +2 more sources

Pseudomonas exotoxin A: toxoid preparation by photoaffinity inactivation. [PDF]

Proceedings of the National Academy of Sciences, 1983
A method for toxoid preparation has been developed in which toxins expressing enzymatic activity can be detoxified by photoaffinity labeling techniques. In the case of Pseudomonas aeruginosa exotoxin A, the method relies on the affinity of azido-substituted analogs of the substrate (NAD) for the proenzyme form of the toxin.
S, Marburg, R L, Tolman, L T, Callahan
openaire   +2 more sources

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Membrane-translocating peptides and toxins: from nature to bedside [PDF]

, 2008
Today, different functional classes of bioactive peptides and toxins isolated from diverse sources of living organisms are known. In medicine, these polypeptides present the potential to be used structurally unmodified or to serve as templates for ...
Hayashi, Mirian Akemi Furuie, Kerkis, Alexandre, Kerkis, Irina, Prieto-Silva, Álvaro Rossan, Rádis-Baptista, Gandhi, Tetsuo, Yamane   +5 more
core   +1 more source

Comparison of Conventional Culture Methods and Polymerase Chain Reaction (PCR) for Specific Detection of Pseudomonas Aeruginosa

مجله دانشکده پزشکی اصفهان, 2012
Background: Pseudomonas aeruginosa (P. aeruginosa), a major gram-negative opportunistic nosocomial pathogen, is notoriously known because of its intrinsic and acquired multiple antibiotic resistances.
Massumeh Doosti, Mehdi Haj Ojagh Faghihi, Ali Ramazani, Mohammad Reza Saini   +3 more
doaj  

A 3D Atlas of Visceral and Somatic Pelvic Motor Neurons in Whole Mounts of Female and Male Rat Spinal Cords

Journal of Comparative Neurology, Volume 533, Issue 11, November 2025.
Visceral and somatic motor neurons (MNs) of the lumbosacral (L6–S1) spinal cord control the genitourinary organs and pelvic striated muscles. We produced a three‐dimensional (3D) MN atlas of the lumbosacral spinal cord using whole‐mount immunostaining, tissue clearing, and advanced 3D microscopy in male and female rats. In so doing, we identified novel
John‐Paul Fuller‐Jackson, Ziying (Alicia) Yang, Nicole M. Wiedmann, Alan Watson, Nathaniel E. C. Jenkins, Janet R. Keast, Peregrine B. Osborne   +6 more
wiley   +1 more source

Low concentrations of local honey modulate ETA expression, and quorum sensing related virulence in drug-resistant Pseudomonas aeruginosa recovered from infected burn wounds [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Honey’s ability to kill microorganisms and even eradication of chronic infections with drug-resistant pathogens has been documented by numerous studies.
Akhter A Ahmed, Fraidoon A Salih
doaj   +1 more source

Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp.

The Journal of Pathology, Volume 267, Issue 3, Page 304-314, November 2025.
Abstract We hypothesized that variants in inflammasome‐related genes could influence susceptibility to gestational malaria (GM). To test this, we conducted an association study in a cohort of pregnant women from a malaria‐endemic region in northern Brazil, assessing whether specific functional single nucleotide variants (SNVs) in inflammasome genes ...
Vinicius NC Leal, Jessica A Ribeiro, Leticia Girardi Marra, Alexandre TT Rio, Edione C Reis, Gerhard Wunderlich, Jamille G Dombrowski, Claudio RF Marinho, Alessandra Pontillo   +8 more
wiley   +1 more source