Results 81 to 90 of about 14,046 (214)

Bacteria in cancer therapy: a novel experimental strategy [PDF]

, 2010
Resistance to conventional anticancer therapies in patients with advanced solid tumors has prompted the need of alternative cancer therapies. Moreover, the success of novel cancer therapies depends on their selectivity for cancer cells with limited ...
S Patyar, R Joshi, DS Prasad Byrav, A Prakash, B Medhi, BK Das   +5 more
core   +2 more sources

Attenuated Strains of Pseudomonas aeruginosa: A Promising Cell Factory for Rhamnolipid Production

Microbial Biotechnology, Volume 18, Issue 11, November 2025.
PGN strains are generated by the deletion of virulence factor genes. The metabolic pathways and regulatory frameworks that lead to high‐efficiency production of rhamnolipids in P. aeruginosa are preserved in these strains. Therefore, PGN strains are promising bio‐safe cell factories for the industrial production of rhamnolipids.
Parvathy V. Das, Meagan E. Valentine, Timothy E. Long, Hongwei D. Yu   +3 more
wiley   +1 more source

Cloning, Expression and Evaluation of Pseudomonas Aeruginosa Exotoxin A

مجله دانشکده پزشکی اصفهان, 2014
Background: Nowadays, in many studies related to the treatment of various cancers, toxic compounds are targeted against cancer cells. One of the most effective compounds is Pseudomonas exotoxin A.
Jahangir Langari, Majid Golkar, Hossein Khanahmad, Morteza Karimipoor, Roghayeh Arezumand, Ramazan Behzadi, Reza Ahangari-Cohan   +6 more
doaj  

Alteration of murine immune response by Pseudomonas aeruginosa exotoxin A [PDF]

Infection and Immunity, 1984
Pseudomonas exotoxin A has been implicated as a possible virulence factor in Pseudomonas infections. This toxin has a direct cytotoxic effect on a number of cell types, including macrophages and their precursors, and therefore may affect other cells of the immune system.
P S, Holt, M L, Misfeldt
openaire   +2 more sources

Peritoneal Immunosurgery: Immunotherapy Augmented Surgery for the Treatment of Peritoneal Cancers

Journal of Surgical Oncology, Volume 132, Issue 5, Page 789-809, October 2025.
ABSTRACT Peritoneal malignancy often indicates disruptions in multiple physiological systems resulting from widespread cancer. The heterogenous origin and dynamic nature of peritoneal cancer make it difficult to treat with standard approaches that fit into guidelines.
Ada I. Ozcan, Arianexys Aquino López, Mary K. McKenna, Malcolm K. Brenner, Alastair M. Thompson   +4 more
wiley   +1 more source

Quorum sensing is not required for twitching motility in Pseudomonas aeruginosa [PDF]

, 2002
It has been reported that mutations in the quorum-sensing genes lasI and rhlI in Pseudomonas aeruginosa result in, among many other things, loss of twitching motility (A. Glessner, R. S. Smith, B. H. Iglewski, and J. B. Robinson, J. Bacteriol.
Beatson, S. A., Whitchurch, C. B., Semmler, A. B. T., Mattick, J. S.   +3 more
core   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, Volume 42, Issue 10, October 2025.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

Type IV Pili Can Mediate Bacterial Motility within Epithelial Cells. [PDF]

, 2019
Pseudomonas aeruginosa is among bacterial pathogens capable of twitching motility, a form of surface-associated movement dependent on type IV pili (T4P). Previously, we showed that T4P and twitching were required for P.
Evans, David J, Fleiszig, Suzanne MJ, Grosser, Melinda R, Hagan, Patrick, Hallsten, Mary E, Kroken, Abby R, Metruccio, Matteo ME, Nieto, Vincent, Smith, Benjamin E   +8 more
core   +2 more sources

Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product‐Based Therapies

Phytotherapy Research, Volume 39, Issue 10, Page 4444-4473, October 2025.
NPs improve atopic dermatitis mainly include flavonoids, phenols, glycosides, alkaloids, and others. ABSTRACT Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients' quality of life, imposes significant psychological strain, and adds to the public health burden.
Xinyun Fan, Zibo Liu, Wenjing Yang, Hongying Zhang, Hao Zhong, Yan Pang, Xun Ye, Chunjie Wu, Liang Li   +8 more
wiley   +1 more source

Molecular detection of virulence factors and biofilm formation in Pseudomonas aeruginosa obtained from different clinical specimens in Bandar Abbas

Iranian Journal of Microbiology, 2019
Background and Objectives: Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen. The presence of several virulence factors such as exotoxin and exoenzyme genes and biofilm may contribute to its pathogenicity.
Nima Bahador, Saeed Shoja, Foroogh Faridi, Banafsheh Dozandeh-Mobarrez, Fatemeh Izadpanah Qeshmi, Sedigheh Javadpour, Sedigheh Mokhtary   +6 more
doaj   +1 more source