Results 11 to 20 of about 35,200 (254)
Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity
Frontiers in Pharmacology, 2018 Platelets are small anucleated cells present only in mammals. Platelets mediate intravascular hemostatic balance, prevent interstitial bleeding, and have a major role in thrombosis.
Milka Koupenova, Katya Ravid
doaj +6 more sources
Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex. [PDF]
PLoS Biology, 2014 Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca(2+)-stimulated release of various gliotransmitters, including glutamate and ATP.
Ulyana Lalo +5 more
doaj +3 more sources
Folia Neuropathologica, 2022 Purinergic signalling is involved in the control of several processes related to brain development, such as neurogenesis and gliogenesis, migration and differentiation of neuronal precursors, synaptogenesis and synaptic elimination to achieve a fully ...
Lidia Babiec +2 more
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Purinergic Receptors in Ocular Inflammation [PDF]
Mediators of Inflammation, 2014 Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease.
Ana Guzman-Aranguez +3 more
doaj +5 more sources
Purinergic receptors in airway hydration. [PDF]
Biochem Pharmacol, 2021 Airway epithelial purinergic receptors control key components of the mucociliary clearance (MCC), the dominant component of pulmonary host defense. In healthy airways, the periciliary liquid (PCL) is optimally hydrated, thus acting as an efficient lubricant layer over which the mucus layer moves by ciliary force.
Lazarowski ER, Boucher RC.
europepmc +3 more sources
Purinergic signalling: past, present and future
Brazilian Journal of Medical and Biological Research, 2009 The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
G. Burnstock
doaj +1 more source
The Role of Purinergic Receptors in the Circadian System [PDF]
International Journal of Molecular Sciences, 2020 Amira A H Ali +2 more
exaly +2 more sources
Purinergic signaling in the male reproductive tract
Frontiers in Endocrinology, 2022 Purinergic receptors are ubiquitously expressed throughout the body and they participate in the autocrine and paracrine regulation of cell function during normal physiological and pathophysiological conditions.
Larissa Berloffa Belardin +4 more
doaj +1 more source
Purinergic Signaling in Liver Pathophysiology
Frontiers in Endocrinology, 2021 Extracellular nucleosides and nucleotides activate a group of G protein-coupled receptors (GPCRs) known as purinergic receptors, comprising adenosine and P2Y receptors. Furthermore, purinergic P2X ion channels are activated by ATP.
Shanu Jain, Kenneth A. Jacobson
doaj +1 more source
P2Y Purinergic Receptors, Endothelial Dysfunction, and Cardiovascular Diseases [PDF]
International Journal of Molecular Sciences, 2020 Alexander D Verin +2 more
exaly +2 more sources