Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity
Platelets are small anucleated cells present only in mammals. Platelets mediate intravascular hemostatic balance, prevent interstitial bleeding, and have a major role in thrombosis.
Milka Koupenova, Katya Ravid
doaj +4 more sources
Purinergic Receptors in Dendritic Cells [PDF]
Miaomiao Wang,1 Xiaoxiao Zhao,1 Shuai Hou,1 Zhongbo Wu,2 Hai-yan Yin1 1School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People’s Republic of China; 2Brain Disease Research Center, Tongren People’s ...
Wang M, Zhao X, Hou S, Wu Z, Yin HY
doaj +4 more sources
Targeting purinergic receptors to attenuate inflammation of dry eye. [PDF]
Inflammation is one of the potential factors to cause the damage of ocular surface in dry eye disease (DED). Increasing evidence indicated that purinergic A_1, A_2A, A_3, P2X4, P2X7, P2Y_1, P2Y_2, and P2Y_4 receptors play an important role in the ...
Wang JN, Fan H, Song JT.
europepmc +2 more sources
Purinergic receptors mediate endothelial dysfunction and participate in atherosclerosis. [PDF]
Atherosclerosis is the main pathological basis of cardiovascular disease and involves damage to vascular endothelial cells (ECs) that results in endothelial dysfunction (ED).
Wu XM +5 more
europepmc +2 more sources
Control of Macrophage Inflammation by P2Y Purinergic Receptors. [PDF]
Macrophages comprise a phenotypically and functionally diverse group of hematopoietic cells. Versatile macrophage subsets engage to ensure maintenance of tissue integrity.
Klaver D, Thurnher M.
europepmc +2 more sources
Purinergic P2 Receptors: Novel Mediators of Mechanotransduction
Mechanosensing and mechanotransduction are vital processes in mechanobiology and play critical roles in regulating cellular behavior and fate. There is increasing evidence that purinergic P2 receptors, members of the purinergic family, play a crucial ...
Qihang Kong +5 more
doaj +3 more sources
Alterations of Purinergic Receptors Levels and Their Involvement in the Glial Cell Morphology in a Pre-Clinical Model of Autism Spectrum Disorders [PDF]
Recent data suggest that defects in purinergic signalling are a common denominator of autism spectrum disorders (ASDs), though nothing is known about whether the disorder-related imbalance occurs at the receptor level.
Lidia Babiec +5 more
doaj +2 more sources
P2 purinergic receptors regulate the progression of colorectal cancer. [PDF]
Zhang WJ +4 more
europepmc +2 more sources
Purinergic Receptors in Ocular Inflammation [PDF]
Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease.
Ana Guzman-Aranguez +3 more
doaj +5 more sources
Purinergic receptors in neurogenic processes.
Neurogenesis is a process of generating functional neurons, which occurs during embryonic and adult stages in mammals. While neurogenesis during development phase is characterized by intensive proliferation activity in all regions of the brain to form ...
D. Ribeiro +3 more
semanticscholar +3 more sources

