Results 21 to 30 of about 571,618 (248)

Purinergic Receptors in Ocular Inflammation [PDF]

open access: yesMediators of Inflammation, 2014
Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease.
Ana Guzman-Aranguez   +3 more
doaj   +5 more sources

Prenatal exposure to valproic acid induces alterations in the expression and activity of purinergic receptors in the embryonic rat brain

open access: yesFolia Neuropathologica, 2022
Purinergic signalling is involved in the control of several processes related to brain development, such as neurogenesis and gliogenesis, migration and differentiation of neuronal precursors, synaptogenesis and synaptic elimination to achieve a fully ...
Lidia Babiec   +2 more
doaj   +2 more sources

Purinergic signalling: past, present and future [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2009
The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
G. Burnstock
doaj   +1 more source

Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity

open access: yesFrontiers in Pharmacology, 2018
Platelets are small anucleated cells present only in mammals. Platelets mediate intravascular hemostatic balance, prevent interstitial bleeding, and have a major role in thrombosis.
Milka Koupenova, Katya Ravid
doaj   +3 more sources

The Role of Purinergic Receptors in the Circadian System [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Charlotte von Gall, Amira A H Ali
exaly   +2 more sources

Purinergic Signaling in Liver Pathophysiology

open access: yesFrontiers in Endocrinology, 2021
Extracellular nucleosides and nucleotides activate a group of G protein-coupled receptors (GPCRs) known as purinergic receptors, comprising adenosine and P2Y receptors. Furthermore, purinergic P2X ion channels are activated by ATP.
Shanu Jain, Kenneth A. Jacobson
doaj   +1 more source

Purinergic signaling in the male reproductive tract

open access: yesFrontiers in Endocrinology, 2022
Purinergic receptors are ubiquitously expressed throughout the body and they participate in the autocrine and paracrine regulation of cell function during normal physiological and pathophysiological conditions.
Larissa Berloffa Belardin   +4 more
doaj   +1 more source

Painful Purinergic Receptors [PDF]

open access: yesThe Journal of Pharmacology and Experimental Therapeutics, 2008
Multiple P2 receptor-mediated mechanisms exist by which ATP can alter nociceptive sensitivity following tissue injury. Evidence from a variety of experimental strategies, including genetic disruption studies and the development of selective antagonists, has indicated that the activation of P2X receptor subtypes, including P2X(3), P2X(2/3), P2X(4) and ...
Diana, Donnelly-Roberts   +4 more
openaire   +2 more sources

Purinergic signaling in the peripheral vestibular system [PDF]

open access: yes, 2022
The inner ear comprises the cochlea and vestibular system, which detect sound and acceleration stimulation, respectively. The function of the inner ear is regulated by ion transport activity among sensory epithelial cells, neuronal cells, non-sensory ...
최재영, 김성헌
core   +1 more source

Purinergic Signaling During Hyperglycemia in Vascular Smooth Muscle Cells

open access: yesFrontiers in Endocrinology, 2020
The activation of purinergic receptors by nucleotides and/or nucleosides plays an important role in the control of vascular function, including modulation of vascular smooth muscle excitability, and vascular reactivity.
Miguel Martin-Aragon Baudel   +3 more
doaj   +1 more source

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