Results 151 to 160 of about 4,625,876 (321)
Neurogastroenterology &Motility, EarlyView.In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley +1 more source
Stem Cells, 2019 In this study, we examined the Ca2+‐permeable Piezo1 channel, a newly identified mechanosensing ion channel, in human dental pulp‐derived mesenchymal stem cells (MSCs) and hypothesized that activation of the Piezo1 channel regulates MSC migration via ...
Fatema Mousawi +7 more
semanticscholar +1 more source
Burning Mouth Syndrome Underlying Factors: A Roadmap From a Network Perspective
Oral Diseases, EarlyView.ABSTRACT Objective To investigate the relationship between biological, psychological, and social factors underlying Burning Mouth Syndrome (BMS). Subjects and Methods A case (n = 40) and control (n = 42) study containing 80 variables was examined using two network models based on regularized partial correlations (n = 82).
Oscar Gabriel Castaño‐Joaqui +3 more
wiley +1 more source
Purinergic receptors in cognitive disturbances
Neurobiology of Disease, 2023 Purinergic receptors (Rs) of the ATP/ADP, UTP/UDP (P2X, P2Y) and adenosine (A1, A2A)-sensitive classes broadly interfere with cognitive processes both under quasi normal and disease conditions.
Peter Illes +3 more
doaj
Veterinary Dermatology, EarlyView.Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki +1 more
wiley +1 more source
Expression of Purinergic Receptor Channels and Their Role in Calcium Signaling and Hormone Release in Pituitary Gonadotrophs [PDF]
, 1996 Melanija Tomić +3 more
openalex +1 more source
Experimental Physiology, EarlyView.Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka +3 more
wiley +1 more source
Mitogenic Signaling by ATP/P2Y Purinergic Receptors in Astrocytes: Involvement of a Calcium-Independent Protein Kinase C, Extracellular Signal-Regulated Protein Kinase Pathway Distinct from the Phosphatidylinositol-Specific Phospholipase C/Calcium Pathway [PDF]
, 1999 Joseph T. Neary +5 more
openalex +1 more source
Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Stimulation of the Shaffer collateral pathway at 3 Hz activates non‐ionotropic NMDA receptors. This subsequently leads to Src kinase mediated phosphorylation of pannexin‐1 (Panx1), which releases ATP from the postsynaptic cell. ATP acts as a ligand for P2X4 receptors to induce long‐term depression (LTD). Abstract In recent years,
Allison C. Nielsen +4 more
wiley +1 more source