Results 91 to 100 of about 7,462 (180)

Purinergic signaling in infectious diseases of the central nervous system

, 2020
Vinícius Santos Alves, Raíssa Leite-Aguiar, Joyce Pereira da Silva, Robson Coutinho‐Silva, Luiz Eduardo Baggio Savio   +4 more
openalex   +2 more sources

Effect and Mechanisms of Yiqi Jianpi Xiaoyu Prescription on Kidney Fibrosis on the Basis of Metabolomics and Experimental Validation

Food Science &Nutrition, Volume 13, Issue 11, November 2025.
Our results demonstrate that YQJPXY alleviates fibrosis by regulating key metabolites, including adenosine, adenine, and inosine, and activates autophagy through the A2BR/cAMP/AMPK pathway. ABSTRACT The Yiqi Jianpi Xiaoyu prescription (YQJPXY) exhibits ameliorative effects on kidney fibrosis, but the underlying mechanism related to metabolism remains ...
Keda Lu, Liqing Ye, Wenze Jiang, Tianyang Cheng, Hong Xia, Peipei Zhang, Bingbing Zhang   +6 more
wiley   +1 more source

Colorectal Cancer and Purinergic Signalling: An Overview. [PDF]

Cancers (Basel), 2022
Roliano GG, Azambuja JH, Brunetto VT, Butterfield HE, Kalil AN, Braganhol E.   +5 more
europepmc   +1 more source

Building Immunocompetent Cerebral Organoids From a Developmental Perspective

Glia, Volume 73, Issue 11, Page 2154-2166, November 2025.
Main Points Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statistical analysis to help develop standardized protocols.
Xabier Cuesta‐Puente, Marco Gonzalez‐Dominguez, Marta Pereira‐Iglesias, Nerea Perez‐Arriazu, Patricia Villegas‐Zafra, Paula Ramos‐Gonzalez, Fabio Cavaliere, Nora Bengoa‐Vergniory, Amanda Sierra   +8 more
wiley   +1 more source

Exploration of the link between gut microbiota and purinergic signalling. [PDF]

Purinergic Signal, 2023
Li M, Liu B, Li R, Yang P, Leng P, Huang Y.   +5 more
europepmc   +1 more source

Purinergic Signaling in Controlling Macrophage and T Cell Functions During Atherosclerosis Development [PDF]

, 2021
Davide Ferrari, Andrea Sala, Daniela Milani, Claudio Celeghini, Fabio Casciano   +4 more
openalex   +1 more source

Web of Science‐Based Visualization of Mapping Global Scientific Production on Epstein–Barr Virus‐Associated Autoimmune Diseases: A Bibliometric Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Epstein–Barr virus (EBV) has been implicated in autoimmune diseases (AIDs), yet a comprehensive analysis of global research trends, knowledge gaps, and translational opportunities remains lacking. Therefore, we aimed to study the research output of EBV‐associated AIDs globally.
Binbin Yu, Baofang Wu, Jian Wang, Shaojie Li, Chunnuan Chen, Zhenlong Liu, Hongzhi Gao   +6 more
wiley   +1 more source

Beyond the surface: P2Y receptor downstream pathways, TLR crosstalk and therapeutic implications for infection and autoimmunity

Pharmacological Research
A successful immune response must effectively obtain pathogen clearance upon infection while preventing excessive collateral tissue damage. It is therefore essential to achieve a nuanced fine regulation of pro- and anti-inflammatory signals to ...
Lena Rueschpler, Sebastian Schloer
doaj   +1 more source

Immunomodulatory Mechanisms of Chronic Wound Healing: Translational and Clinical Relevance

MedComm, Volume 6, Issue 11, November 2025.
This graphical abstract illustrates the immunomodulation of chronic wounds through various therapeutic approaches aimed at regulating the immune response to promote healing. ABSTRACT Chronic wounds—such as diabetic foot ulcers (DFUs), pressure ulcers (PUs), and venous leg ulcers (VLUs)—pose a serious clinical challenge due to their prolonged ...
Mahrukh Riaz, Muhammad Zohaib Iqbal, Agnes S. Klar, Thomas Biedermann   +3 more
wiley   +1 more source

Apoptotic Osteocytes Induce RANKL Production in Bystanders via Purinergic Signaling and Activation of Pannexin Channels [PDF]

, 2020
Sean McCutcheon, Robert J. Majeska, David C. Spray, Mitchell B. Schaffler, Maribel Vázquez   +4 more
openalex   +1 more source