Results 91 to 100 of about 4,625,657 (223)

Editorial: Special issue on purinergic signalling and calcification. [PDF]

Purinergic Signal, 2023
Orriss IR, Arnett TR.
europepmc   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, EarlyView.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Mitogenic Signaling by ATP/P2Y Purinergic Receptors in Astrocytes: Involvement of a Calcium-Independent Protein Kinase C, Extracellular Signal-Regulated Protein Kinase Pathway Distinct from the Phosphatidylinositol-Specific Phospholipase C/Calcium Pathway [PDF]

, 1999
Joseph T. Neary, Yuan Kang, Yurong Bu, Esther J. Yu, Katherine Akong, Christopher M. Peters   +5 more
openalex   +1 more source

Inhibition and potentiation of the exercise pressor reflex by pharmacological modulation of TRPC6 in male rats

The Journal of Physiology, EarlyView.
Abstract figure legend The majority of L4–L5 dorsal root ganglion cells innervating the triceps surae muscles of healthy rats expressed TRPC6 channels. In decerebrated rats, pharmacological inhibition of TRPC6 channels by injection of antagonists (SAR7334 or BI‐749327) into the arterial supply of the triceps surae muscles inhibited the exercise pressor
Guillaume P. Ducrocq, Laura Anselmi, Salvatore L. Stella Jr, Steven W. Copp, Victor Ruiz‐Velasco, Marc P. Kaufman   +5 more
wiley   +1 more source

Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model

Molecular Pain, 2011
Background A genetic knock-in mouse model expressing the R192Q mutation of the α1-subunit of the CaV2.1 channels frequently found in patients with familial hemiplegic migraine shows functional upregulation of ATP-sensitive P2X3 receptors of trigeminal ...
Fabbretti Elsa, van den Maagdenberg Arn MJM, Sundukova Mayya, Gnanasekaran Aswini, Nistri Andrea   +4 more
doaj   +1 more source

Expression of Purinergic Receptor Channels and Their Role in Calcium Signaling and Hormone Release in Pituitary Gonadotrophs [PDF]

, 1996
Melanija Tomić, Richard M. Jobin, Leoncio Vergara, Stanko S. Stojilković   +3 more
openalex   +1 more source

Chemoreflex function in pulmonary diseases – A review

The Journal of Physiology, EarlyView.
Abstract figure legend Chemoreflex activation in respiratory diseases and COVID‐19 populations. Abstract The chemoreflex is a vital protective reflex that is crucial in restoring normal blood gas and pH levels. The carotid bodies are peripheral chemoreceptors activated by hypoxia (primarily), hypercapnia, acidaemia, temperature, lactate and potassium ...
Kajal Kamra, Zhiqiu Xia, Irving H. Zucker, Harold Schultz, Han‐Jun Wang   +4 more
wiley   +1 more source

Modulation of Interleukin-1β and Tumor Necrosis Factor α Signaling by P2 Purinergic Receptors in Human Fetal Astrocytes [PDF]

, 2000
Judy S. H. Liu, Gareth John, Andrew G. Sikora, S C Lee, Celia F. Brosnan   +4 more
openalex   +1 more source

Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sphingosine‐1‐phosphate (S1P) binds to Gi protein‐coupled receptor S1PR1. Upon S1PR1 activation, Gβγ is released from the Gαi‐Gβγ heterotrimer, allowing it to recruit phospholipase Cβ (PLCβ) to the plasma membrane. PLCβ cleaves phosphatidylinositol‐4,5‐bisphosphate (PIP2) into inositol trisphosphate (IP3) and diacylglycerol (DAG).
Yulia Kostritskaia, Sumaira Pervaiz, Anna Klemmer, Malte Klüssendorf, Tobias Stauber   +4 more
wiley   +1 more source

Purinergic receptor antagonists inhibit odorant-mediated CREB phosphorylation in sustentacular cells of mouse olfactory epithelium

BMC Neuroscience, 2011
Background Extracellular nucleotides have long been known to play neuromodulatory roles and to be involved in intercellular signalling. In the olfactory system, ATP is released by olfactory neurons, and exogenous ATP can evoke an increase in ...
Hatt Hanns, Toetter Bastian, Mashukova Anastasia, Dooley Ruth, Neuhaus Eva M   +4 more
doaj   +1 more source