Results 121 to 130 of about 4,625,657 (223)

A Novel Catalytically Inactive Construct of Botulinum Neurotoxin A (BoNT/A) Directly Inhibits Visceral Sensory Signalling

Toxins
Botulinum neurotoxin A (BoNT/A) is a potent neurotoxin that silences cholinergic neurotransmission through the cleavage of the synaptic protein SNAP-25.
Hodan Ibrahim, Kevin Retailleau, Fraser Hornby, Jacquie Maignel, Matthew Beard, Donna Marie Daly   +5 more
doaj   +1 more source

The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract Enteric glia are a heterogeneous population of peripheral glia within the enteric nervous system and play pivotal roles in gut homeostasis, tissue integrity, coordination of motility, and intestinal immune responses. Under physiological conditions, they communicate with enteric neurons to control intestinal motility.
Schneider Reiner, Schneider Linda, Hamza Ebrahim, Leven Patrick, Wehner Sven   +4 more
wiley   +1 more source

Participation of the Lys313-Ile333 Sequence of the Purinergic P2X4 Receptor in Agonist Binding and Transduction of Signals to the Channel Gate [PDF]

, 2006
Zonghe Yan, Zhaodong Liang, Tomáš Obšil, Stanko S. Stojilković   +3 more
openalex   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling. [PDF]

Elife, 2022
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC.   +34 more
europepmc   +1 more source

Characterization of an alternative splice variant of human nucleoside triphosphate diphosphohydrolase 3 (NTPDase3): A possible modulator of nucleotidase activity and purinergic signaling [PDF]

, 2006
Patrick A. Crawford, Keith J. Gaddie, Thomas M. Smith, Terence L. Kirley   +3 more
openalex   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

Veterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki, Santosh K. Mishra   +1 more
wiley   +1 more source

Purinergic signalling in the urinary bladder - When function becomes dysfunction. [PDF]

Auton Neurosci, 2021
Fry CH, McCloskey KD.
europepmc   +1 more source

Signal transduction mechanism of P2-purinergic receptors in thyroid cells.

, 1991
Fumikazu Okajima, Hideaki Tomura, Kōichi Sato, Martina Nazarea, Kimie Sho, Yoichi Kondo   +5 more
openalex   +1 more source

Purinergic signalling in the immune system. A brief update [PDF]

, 2007
Francesco Di Virgilio
openalex   +1 more source