Results 151 to 160 of about 4,754,967 (333)
P2 purinoceptors signaling in fibroblasts of rat subcutaneous tissue [PDF]
, 2011 Mestrado em Biologia Molecular e CelularO tecido conjuntivo parece estar envolvido na génese de diversas condições patológicas. O aumento da rigidez do tecido conjuntivo, resultante da fibrose, pode constituir um factor importante no mecanismo patogénico
Reis, Carla Patrícia da Silva e Sousa
core +1 more source
The actions of Pasteurella multocida toxin on neuronal cells [PDF]
, 2014 Pasteurella multocida toxin (PMT) activates the G-proteins Gα, Gα, Gα Gα and Gα by deamidation of specific glutamine residues. A number of these alpha subunits have signalling roles in neurones.
Duricki, DA +4 more
core +1 more source
The FEBS Journal, EarlyView.The adenylyl cyclase (AC) Rv1625c from M. tuberculosis is a monomeric progenitor of the nine pseudoheterodimeric mammalian AC isoforms. The hexahelical membrane anchor of Rv1625c serves as an inhibitory receptor for fatty acids, particularly oleic acid. One ligand binds into each monomer of the active Rv1625c dimer.
Anita Charlotte Friderun Schultz +3 more
wiley +1 more source
Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst [PDF]
, 2009 Background. Dinucleoside polyphosphates (NpnN) have pathophysiologic roles in cardiovascular disease and are newly detected uraemic retention solutes. They were retrieved in human plasma, tissues and cells.
Dhondt, Annemieke +5 more
core +1 more source
Mind the GAPS: Glia associated with psychological stress
Journal of Neuroendocrinology, EarlyView.Abstract Glial cells are an integral component of the nervous system, performing crucial functions that extend beyond structural support, including modulation of the immune system, tissue repair, and maintaining tissue homeostasis. Recent studies have highlighted the importance of glial cells as key mediators of stress responses across different organs.
Niklas Blank +4 more
wiley +1 more source
Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells
Cell Communication and Signaling, 2015 In many cells, bile acids (BAs) have a multitude of effects, some of which may be mediated by specific receptors such the TGR5 or FXR receptors. In pancreas systemic BAs, as well as intra-ductal BAs from bile reflux, can affect pancreatic secretion ...
J. Kowal +3 more
semanticscholar +1 more source
The human colon: Evidence for degenerative changes during aging and the physiological consequences
Neurogastroenterology &Motility, EarlyView.Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley +1 more source
Abstract Geometrical Computation 10: An Intrinsically Universal Family of Signal Machines [PDF]
arXiv, 2018 Signal machines form an abstract and idealised model of collision computing. Based on dimensionless signals moving on the real line, they model particle/signal dynamics in Cellular Automata. Each particle, or signal, moves at constant speed in continuous time and space. When signals meet, they get replaced by other signals. A signal machine defines the
arxiv
Journal of Neuroscience, 2015 The mechanisms of neurovascular coupling underlying generation of BOLD fMRI signals remain incompletely understood. It has been proposed that release of vasoactive substances by astrocytes couples neuronal activity to changes in cerebrovascular blood ...
J. Wells +11 more
semanticscholar +1 more source
Purinergic Signalling in Physiology and Pathophysiology. [PDF]
Int J Mol Sci, 2023 Sluyter R.
europepmc +1 more source