Results 191 to 200 of about 4,754,967 (333)

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, EarlyView.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

Purinergic signaling in schistosomal infection

Biomedical Journal, 2016
Human schistosomiasis is a chronic inflammatory disease caused by blood fluke worms belonging to the genus Schistosoma. Health metrics indicate that the disease is related to an elevated number of years lost-to-disability and years lost-to-life. Schistosomiasis is an intravascular disease that is related to a Th1 and Th2 immune response polarization ...
openaire   +4 more sources

Evidence for the involvement of purinergic signalling in the control of respiration [PDF]

, 2001
T Thomas, Vera Ralevic, Michelle Bardini, Geoffrey Burnstock, K. Michael Spyer   +4 more
openalex   +1 more source

Burnstock oration - purinergic signalling in kidney transplantation. [PDF]

Purinergic Signal, 2022
Dwyer KM.
europepmc   +1 more source

Inhibition and potentiation of the exercise pressor reflex by pharmacological modulation of TRPC6 in male rats

The Journal of Physiology, EarlyView.
Abstract figure legend The majority of L4–L5 dorsal root ganglion cells innervating the triceps surae muscles of healthy rats expressed TRPC6 channels. In decerebrated rats, pharmacological inhibition of TRPC6 channels by injection of antagonists (SAR7334 or BI‐749327) into the arterial supply of the triceps surae muscles inhibited the exercise pressor
Guillaume P. Ducrocq, Laura Anselmi, Salvatore L. Stella Jr, Steven W. Copp, Victor Ruiz‐Velasco, Marc P. Kaufman   +5 more
wiley   +1 more source

Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?

Journal of Innate Immunity
Background: Interstitial lung diseases (ILD) are poorly understood disorders characterised by diffuse damage to the lung parenchyma, with inflammation and fibrosis.
Luke Forde, Debananda Gogoi, Rory Baird, Cormac McCarthy, Michael P. Keane, Emer P. Reeves, Emmet E. McGrath   +6 more
doaj   +1 more source

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

Journal of Bone Oncology, 2021
Background: Osteosarcoma (OS) is the most common type of primary bone cancer affecting children and adolescents. OS has a high propensity to spread meaning the disease is often incurable and fatal.
Luke Tattersall, Karan M. Shah, Darren L. Lath, Archana Singh, Jennifer M. Down, Elena De Marchi, Alex Williamson, Francesco Di Virgilio, Dominique Heymann, Elena Adinolfi, William D. Fraser, Darrell Green, Michelle A. Lawson, Alison Gartland   +13 more
doaj  

Signal Transformation for Effective Multi-Channel Signal Processing [PDF]

arXiv
Electroencephalography (EEG) is an non-invasive method to record the electrical activity of the brain. The EEG signals are low bandwidth and recorded from multiple electrodes simultaneously in a time synchronized manner. Typical EEG signal processing involves extracting features from all the individual channels separately and then fusing these features
arxiv  

Potential therapeutic targets in the rapidly expanding field of purinergic signalling [PDF]

, 2002
Geoffrey Burnstock
openalex   +1 more source

Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sphingosine‐1‐phosphate (S1P) binds to Gi protein‐coupled receptor S1PR1. Upon S1PR1 activation, Gβγ is released from the Gαi‐Gβγ heterotrimer, allowing it to recruit phospholipase Cβ (PLCβ) to the plasma membrane. PLCβ cleaves phosphatidylinositol‐4,5‐bisphosphate (PIP2) into inositol trisphosphate (IP3) and diacylglycerol (DAG).
Yulia Kostritskaia, Sumaira Pervaiz, Anna Klemmer, Malte Klüssendorf, Tobias Stauber   +4 more
wiley   +1 more source