Results 41 to 50 of about 162,902 (284)

ATP and Adenosine in the Retina and Retinal Diseases

open access: yesFrontiers in Pharmacology, 2021
Extracellular ATP and its ultimate degradation product adenosine are potent extracellular signaling molecules that elicit a variety of pathophysiological pathways in retina through the activation of P2 and P1 purinoceptors, respectively.
Shan-Shan Ye   +3 more
doaj   +1 more source

Purinergic mechanosensory transduction and visceral pain [PDF]

open access: yes, 2009
In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain.
Burnstock, G
core   +3 more sources

Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC [PDF]

open access: yes, 2012
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways.
Alberto Contreras-Sanz   +60 more
core   +2 more sources

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release [PDF]

open access: yes, 2017
Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in ...
Arnett, T R   +5 more
core   +2 more sources

Purinergic Signaling in the Hallmarks of Cancer [PDF]

open access: yesCells, 2020
Cancer is a complex expression of an altered state of cellular differentiation associated with severe clinical repercussions. The effort to characterize this pathological entity to understand its underlying mechanisms and visualize potential therapeutic strategies has been constant.
Anaí del Rocío Campos-Contreras   +2 more
openaire   +4 more sources

A Systematic Review of the Expression, Signalling and Function of P2 Receptors in Primary Bone Cancer

open access: yesFrontiers in Bioscience-Landmark, 2022
Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of the
Luke Tattersall   +5 more
doaj   +1 more source

Reversible Joint Hilbert and Linear Canonical Transform Without Distortion [PDF]

open access: yesIEEE Transactions on Signal Processing, Volume 61, Issue 19, Oct.1, 2013, 2017
Generalized analytic signal associated with the linear canonical transform (LCT) was proposed recently by Fu and Li ["Generalized Analytic Signal Associated With Linear Canonical Transform," Opt. Commun., vol. 281, pp. 1468-1472, 2008]. However, most real signals, especially for baseband real signals, cannot be perfectly recovered from their ...
arxiv   +1 more source

Short- and long-term (trophic) purinergic signalling [PDF]

open access: yes, 2016
There is long-term (trophic) purinergic signalling involving cell proliferation, differentiation, motility and death in the development and regeneration of most systems of the body, in addition to fast purinergic signalling in neurotransmission ...
Burnstock, G
core   +1 more source

Signal Structure of the Starlink Ku-Band Downlink [PDF]

open access: yes, 2022
We develop a technique for blind signal identification of the Starlink downlink signal in the 10.7 to 12.7 GHz band and present a detailed picture of the signal's structure. Importantly, the signal characterization offered herein includes the exact values of synchronization sequences embedded in the signal that can be exploited to produce pseudorange ...
arxiv   +1 more source

Purinergic Signalling and Neurological Diseases: An Update [PDF]

open access: yes, 2017
Purinergic signalling, i.e. ATP as an extracellular signalling molecule and cotransmitter in both peripheral and central neurons, is involved in the physiology of neurotransmission and neuromodulation.
Burnstock, G
core   +1 more source

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