Results 61 to 70 of about 7,462 (180)
The role of ectonucleotidases CD39 and CD73 and adenosine signalling in solid organ transplantation
Extracellular adenosine is a potent immunomodulatory molecule that accumulates in states of inflammation. Nucleotides such as adenosine triphosphate (ATP) and adenosine diphosphate (ADP) are release from injured and necrotic cells and hydrolysed to ...
Veena eRoberts +2 more
doaj +1 more source
Abstract Epilepsy affects approximately 1% of the population worldwide, and although medications are effective in the majority of cases, seizures persist in approximately 30% of patients. Despite the effort to develop new antiseizure drugs, the rate of pharmacoresistance in patients has not diminished over the past 3 decades. There is thus a real unmet
Vincent Magloire +9 more
wiley +1 more source
Abstract Objective Studies in temporal lobe epilepsy (TLE) have shown that focal inflammation is a key contributor to seizure initiation and maintenance. However, most in vivo studies to date have focused on positron emission tomography (PET) findings. In this exploratory study, we assessed the relationship between multicompartment Neurite Orientation ...
Jerzy P. Szaflarski +6 more
wiley +1 more source
Morpho‐Histo‐Cytological Evaluation of Oral Tissues in Burning Mouth Syndrome: A Systematic Review
This systematic review on Burning Mouth Syndrome (BMS) included 14 studies that examined histological changes. 12 studies used incisional biopsies and 2 used exfoliative cytology. Histology and molecular biology techniques were used to assess morphological, phenotypical and genomic changes in oral tissues, primarily from the tongue.
André Luís Porporatti +8 more
wiley +1 more source
Optimization of photobiomodulation therapy for spinal cord injury: A review
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew +3 more
wiley +1 more source
The anti-inflammatory astrocyte revealed: the role of the microbiome in shaping brain defences
Alexei Verkhratsky +3 more
doaj +1 more source
Purinergic Signalling in Physiology and Pathophysiology. [PDF]
Sluyter R.
europepmc +1 more source
Glial cells in the heart: Implications for their roles in health and disease
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya +2 more
wiley +1 more source
Inflammatory cells that infiltrate and surround the airway smooth muscle (ASM) layer express antimicrobial peptides including the cathelicidin LL-37.
Suzanne Zuyderduyn +3 more
doaj
Editorial: Purinergic signalling - a perspective from China. [PDF]
Tang Y, Chen JF, Illes P.
europepmc +1 more source

