Anti-Tubercular Drug-Induced Liver Injury: Current Understanding and Emerging Directions. [PDF]
JGH OpenABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Prasad S, Narang H, Kedia S, Ahuja V.
europepmc +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Frontiers in Microbiology, 2021 Pyrazinamide (PZA) is widely used to treat drug-sensitive or multidrug resistance tuberculosis. However, conventional PZA susceptibility tests of clinical isolates are rather difficult because of the requirement of acid pH.
Kun Li +6 more
doaj +1 more source
A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]
, 2017 Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A +7 more
core +1 more source
Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection. [PDF]
, 2016 Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB.
Bangsberg +41 more
core +2 more sources
The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors
Frontiers in Microbiology, 2021 Given the upsurge of drug-resistant tuberculosis worldwide, there is much focus on developing novel drug combinations allowing shorter treatment duration and a lower toxicity profile.
Kyle H. Rohde, Leonardo Sorci
doaj +1 more source
Breast tuberculosis in Northeast Iran: Review of 22 cases [PDF]
, 2014 Background: Breast tuberculosis (breast TB) is an extremely rare disease, so case reviews are also rare.Methods: This study is a retrospective review of patients with breast TB who were treated between 2002 and 2012 at the Health Center of Gorgan City ...
Khodabakhshi, B., Mehravar, F.
core +2 more sources
PYRAZINAMIDE INDUCED ACUTE GOUTY ARTHRITIS
Journal of Nepal Medical Association, 2003 A typical case of pyrazinamide induced acute gouty arthritis in a tuberculous patient with antitubercular therapy including pyrazinamide was reported.
U N Pathak, B O Shrestha, R R Shrestha
doaj +1 more source
Drug Analytical Research, 2021 The ultraviolet spectrophotometry analysis for quantitative assay of drugs is a method accurate, sensitive, selective and reproductive with the advantage of being a simple and less expensive method.
Morgana Souza Marques +3 more
doaj +1 more source
Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]
, 2018 Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla +8 more
core +1 more source