Drug Analytical Research, 2021 The ultraviolet spectrophotometry analysis for quantitative assay of drugs is a method accurate, sensitive, selective and reproductive with the advantage of being a simple and less expensive method.
Morgana Souza Marques +3 more
doaj +1 more source
Designing molecular diagnostics for current tuberculosis drug regimens
Emerging Microbes and Infections, 2023 Diagnostic development must occur in parallel with drug development to ensure the longevity of new treatment compounds. Despite an increasing number of novel and repurposed anti-tuberculosis compounds and regimens, there remains a large number of drugs ...
Sophia B. Georghiou +9 more
doaj +1 more source
Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis. [PDF]
, 2016 BackgroundTuberculosis (TB) is the leading cause of death from an infectious pathogen worldwide and the most prevalent opportunistic infection in people living with HIV.
Bacchetti, Peter +6 more
core +1 more source
Mechanistic Modeling of Mycobacterium tuberculosis Infection in Murine Models for Drug and Vaccine Efficacy Studies. [PDF]
, 2020 Tuberculosis (TB) drug, regimen, and vaccine development rely heavily on preclinical animal experiments, and quantification of bacterial and immune response dynamics is essential for understanding drug and vaccine efficacy.
Nuermberger, Eric L +6 more
core +1 more source
First report of multi-drug resistant tuberculosis in a systemic lupus erythematosus patient. [PDF]
, 2015 BackgroundTreatment of a multi-drug resistant tuberculosis (MDR-TB) patient is clinically challenging, requiring a minimum of 18 months of therapy. Its occurrence in a systemic lupus erythromatosus (SLE) patient may complicate management of both MDR-TB ...
Dierberg, Kerry L +3 more
core +1 more source
Туберкулез и болезни лёгких, 2017 The level of uric acid in blood serum was investigated in 134 new patients suffering from multiple drug resistant pulmonary tuberculosis (78 men and 56 women). The tests were performed by admission to hospital and then repeated in 1, 2, 3, 4, 5, 6, 7 and
R. Yu. Аbdullaev +3 more
doaj +1 more source
A 34-Year-Old Obese Woman with Rash, Finger Swelling and Fever
International Journal of Infectious Diseases, 2017 Disseminated tuberculosis first presenting as cutaneous lesion is uncommon and difficult to diagnose on account of its divers clinical forms. We present a 34-year-old obese woman with rash, finger swelling and fever. The patient was firstly manifested by
Na Huo +6 more
doaj +1 more source
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain [PDF]
, 2015 The rise of drug-resistant strains is a major challenge to containing the tuberculosis (TB) pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy and when transmission of resistant strains on a larger scale became a
Balloux, Francois +6 more
core +4 more sources
Antimicrobial Activity of Pyrazinamide Coordination Frameworks Synthesized by Mechanochemistry
Molecules, 2021 The urge for the development of a more efficient antibiotic crystalline forms led us to the disclosure of new antibiotic coordination frameworks of pyrazinamide, a well-known drug used for the treatment of tuberculosis, with some of the novel compounds ...
Sílvia Quaresma +4 more
doaj +1 more source
Risk of acquired drug resistance during short-course directly observed treatment of tuberculosis in an area with high levels of drug resistance. [PDF]
, 2007 BACKGROUND: Data on the performance of standardized short-course directly observed treatment (DOTS) of tuberculosis (TB) in areas with high levels of drug resistance and on the potential impact of DOTS on amplification of resistance are limited ...
Cox +33 more
core +2 more sources