Results 11 to 20 of about 26,737 (201)
Pyrazinamide-induced maculopapular rash
Indian Journal of Dermatology, 2010 Pyrazinamide is a commonly used first-line antitubercular drug. Gastric-related adverse drug reactions are common with pyrazinamide. Dermatological manifestations due to pyrazinamide are rare.
Khayyam Khalid +4 more
doaj +2 more sources
Optimizing pyrazinamide for the treatment of tuberculosis [PDF]
, 2021 Pyrazinamide is a potent sterilizing agent that shortens the treatment duration needed to cure tuberculosis. It is synergistic with novel and existing drugs for tuberculosis.
Morlock, Glenn +20 more
core +1 more source
Novel Pyrazole-4-Carbaldehyde Derivatives Having Potent COX-2 Inhibition and Anti-Tubercular Activity: Microwave-Assisted Green Synthesis and Molecular Docking. [PDF]
J Biochem Mol ToxicolABSTRACT A series of 1‐(4‐Chorophenyl)‐3Aryl‐1‐H‐pyrazole‐4‐carbaldehyde derivatives were synthesized under the microwave irradiation (MW) technique. IR, 1H‐NMR, 13C‐NMR, and mass spectroscopic techniques were used to confirm the structure of the synthesized compounds.
Kokane M +6 more
europepmc +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Pyrazinamide-3-Nitrophthalic Acid Cocrystals: Synthesis, Transformation, and Property Evaluation
, 2023 The generation of multiple stoichiometric cocrystals from safe and nontoxic water is a rare occurrence. This study explored three different stoichiometric cocrystals (1:1, 1:2, and 2:1) of pyrazinamide-3-nitrophthalic acid cocrystals characterized by ...
Xiaohan Li (276434) +6 more
core +1 more source
The Phase Relationship Between the Pyrazinamide Polymorphs α and γ [PDF]
, 2019 Pyrazinamide is an active pharmaceutical compound for the treatment of tuberculosis. It possesses at least four crystalline polymorphs. Polymorphism may cause solubility problems as the case of ritonavir has clearly demonstrated; however ...
Kangli, Li +6 more
core +2 more sources
Frontiers in Cell and Developmental Biology, 2022 Rifampicin (RIF), Isoniazid (INH), Ethambutol (EMB), Pyrazinamide (PZA), and/or their fixed-dose combination (FDC) are extensively prescribed in the cure of Tuberculosis (TB) globally.
Adekunle A. Bakare +11 more
doaj +1 more source
Protective role of taurine against hepatotoxicity induced by pyrazinamide in rats
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Pyrazinamide is a widely used antituberculosis drug. However, associated with its clinical use, hepatotoxicity is a life-threating side effect reported in some patients, but the exact mechanism by which pyrazinamide induces hepatotoxicity is ...
Shohreh Taziki +5 more
doaj +1 more source
Inorganics, 2022 The global demand on adipic usage in the production of plasticizers and synthetic polyamide is increasing. In line with the search for an efficient and energy-conserving way to isolate adipic acid (AA) in good yields, this paper introduces the ...
Adedibu C. Tella +6 more
doaj +1 more source
Synthesis, Biological Evaluation, and In Silico Modeling of N-Substituted Quinoxaline-2-Carboxamides
Pharmaceuticals, 2021 Despite the established treatment regimens, tuberculosis remains an alarming threat to public health according to WHO. Novel agents are needed to overcome the increasing rate of resistance and perhaps achieve eradication.
Ghada Bouz +7 more
doaj +1 more source