Results 31 to 40 of about 38,381 (252)
Risk of acquired drug resistance during short-course directly observed treatment of tuberculosis in an area with high levels of drug resistance. [PDF]
, 2007 BACKGROUND: Data on the performance of standardized short-course directly observed treatment (DOTS) of tuberculosis (TB) in areas with high levels of drug resistance and on the potential impact of DOTS on amplification of resistance are limited ...
Cox +33 more
core +2 more sources
Pyrazinamide may possess cardioprotective properties [PDF]
, 2019 Pyrazinamide is an anti-tubercular agent, used as a part of a three-drug regime (any three of the following: rifampicin, isoniazid, pyrazinamide, streptomycin or ethambutol) for the initial phase of treatment.
Du, Qingyou +4 more
core +2 more sources
Molecules, 2013 5-Chloropyrazinamide (5-Cl-PZA) is an inhibitor of mycobacterial fatty acid synthase I with a broad spectrum of antimycobacterial activity in vitro. Some N-phenylpyrazine-2-carboxamides with different substituents on both the pyrazine and phenyl core ...
Jan Zitko +9 more
doaj +1 more source
Protective Effect of Bicyclol on Anti-Tuberculosis Drug Induced Liver Injury in Rats
Molecules, 2017 The present study was performed to investigate the effect of bicyclol, a synthetic anti-hepatitis drug with anti-oxidative and anti-inflammatory properties, on anti-tuberculosis (anti-TB) drug-induced liver injury and related mechanisms in rats. Bicyclol
Xin Liu +5 more
doaj +1 more source
Pharmaceuticals, 2023 Self-emulsifying drug delivery systems (SEDDSs) are lipid-based systems that are superior to other lipid-based oral drug delivery systems in terms of providing drug protection against the gastrointestinal (GI) environment, inhibition of drug efflux as ...
Daniélle van Staden +2 more
doaj +1 more source
Recurrent Cutaneous Tuberculosis in an Immunocompetent 7-Year-Old Male [PDF]
, 2018 Cutaneous tuberculosis (TB) makes up a small proportion of the 10.4 million cases around the world. Although it is more commonly found in the developing world, cutaneous TB is rarely reported in the developed countries.
Austin, Dena +4 more
core +2 more sources
Symptomatic central nervous system tuberculoma, a case report in the United States and literature review [PDF]
, 2019 Intracranial tuberculoma is one of the rare central nervous system manifestations of Mycobacterium tuberculosis (MTB), seen in only 1% of tuberculosis patients.
Butt, Saira, Mohammadian, Mahsa
core +1 more source
Drug rash with eosinophilia and systemic symptoms syndrome due to anti-TB medication
Journal of Family Medicine and Primary Care, 2013 Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe, idiosyncratic, multi-system reaction characterized by the clinical triad of fever, rash, and internal organ involvement.
Dharmesh H Kaswala
doaj +1 more source
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. [PDF]
, 2018 Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available datasets describing its AMR characteristics demand disparate data-type analyses ...
Anand, Amitesh +11 more
core +2 more sources
Clinical Pharmacology &Therapeutics, EarlyView.Multiple imputation is well‐established for handling missing data, yet its use in high‐dimensional genetic datasets remains limited. Using pharmacokinetic tuberculosis simulations and SNP data (1000 Genomes Project), we compared machine learning (ML) and traditional approaches (e.g., mean imputation and complete‐case analysis) for imputation and ...
Innocent G. Asiimwe +6 more
wiley +1 more source