Results 31 to 40 of about 35,915 (205)
Pyrazinamide may possess cardioprotective properties [PDF]
, 2019 Pyrazinamide is an anti-tubercular agent, used as a part of a three-drug regime (any three of the following: rifampicin, isoniazid, pyrazinamide, streptomycin or ethambutol) for the initial phase of treatment.
Du, Qingyou +4 more
core +2 more sources
Rechallenge after anti-tuberculosis drug-induced liver injury in a high HIV prevalence cohort
Southern African Journal of HIV Medicine, 2022 Background: There are limited data on the outcomes of rechallenge with anti-tuberculosis therapy (ATT) following anti-tuberculosis drug-induced liver injury (AT-DILI) in a high HIV prevalence setting.
Muhammed Shiraz Moosa +8 more
doaj +1 more source
Recurrent Cutaneous Tuberculosis in an Immunocompetent 7-Year-Old Male [PDF]
, 2018 Cutaneous tuberculosis (TB) makes up a small proportion of the 10.4 million cases around the world. Although it is more commonly found in the developing world, cutaneous TB is rarely reported in the developed countries.
Austin, Dena +4 more
core +2 more sources
Molecules, 2019 Vibrational modes of pyrazinamide (PZA), 3-hydroxybenzoic acid (3-hBA), and their cocrystal were characterized using terahertz time-domain (THz-TDS) and Raman vibrational spectroscopic techniques.
Qiqi Wang, Jiadan Xue, Zhi Hong, Yong Du
doaj +1 more source
Microbiology Spectrum, 2023 Prediction of susceptibility to pyrazinamide (PZA) directly from sputum has been challenging. The MeltPro MTB/PZA assay, based on melting curve analysis, can simultaneously detect Mycobacterium tuberculosis and the resistance to PZA from sputum. We aimed
Rong Li +15 more
doaj +1 more source
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance. [PDF]
, 2018 Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available datasets describing its AMR characteristics demand disparate data-type analyses ...
Anand, Amitesh +11 more
core +2 more sources
Symptomatic central nervous system tuberculoma, a case report in the United States and literature review [PDF]
, 2019 Intracranial tuberculoma is one of the rare central nervous system manifestations of Mycobacterium tuberculosis (MTB), seen in only 1% of tuberculosis patients.
Butt, Saira, Mohammadian, Mahsa
core +1 more source
Molecules, 2013 5-Chloropyrazinamide (5-Cl-PZA) is an inhibitor of mycobacterial fatty acid synthase I with a broad spectrum of antimycobacterial activity in vitro. Some N-phenylpyrazine-2-carboxamides with different substituents on both the pyrazine and phenyl core ...
Jan Zitko +9 more
doaj +1 more source
Protective Effect of Bicyclol on Anti-Tuberculosis Drug Induced Liver Injury in Rats
Molecules, 2017 The present study was performed to investigate the effect of bicyclol, a synthetic anti-hepatitis drug with anti-oxidative and anti-inflammatory properties, on anti-tuberculosis (anti-TB) drug-induced liver injury and related mechanisms in rats. Bicyclol
Xin Liu +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source