Results 111 to 120 of about 12,838 (166)

Molecular characterization of pyrazinamide resistance in Mycobacterium tuberculosis

, 2015
Tuberculosis (TB) is a highly infectious disease that causes the second highest mortality rate in human worldwide. The emergence of multi-drug resistance tuberculosis (MDR-TB) leads to a major public health problem in controlling TB-caused mortality. Pyrazinamide (PZA) is an important first-line drug in the treatment of MDR-TB.
openaire   +2 more sources

Mechanistic analysis of A46V, H57Y, and D129N in pyrazinamidase associated with pyrazinamide resistance. [PDF]

Saudi J Biol Sci, 2020
Khan MT, Chinnasamy S, Cui Z, Irfan M, Wei DQ.   +4 more
europepmc   +1 more source

Toward precision detection of pyrazinamide resistance: critical concentration assessment and rapid molecular method validation. [PDF]

Front Microbiol
Zhao Y, Tian L, Wang N, Chen H, Chen S, Yu L, Pang M, Ding B, Li J, Li C, Dai X.   +10 more
europepmc   +1 more source

Immunological detection of pyrazine-2-carboxylic acid for the detection of pyrazinamide resistance in Mycobacterium tuberculosis. [PDF]

PLoS One, 2020
Florentini EA, Angulo N, Gilman RH, Alcántara R, Roncal E, Antiparra R, Toscano E, Vallejos K, Kirwan D, Zimic M, Sheen P.   +10 more
europepmc   +1 more source

Pyrazinamide Resistance and Mutation Patterns Among Multidrug-Resistant Mycobacterium tuberculosis from Henan Province. [PDF]

Infect Drug Resist, 2020
Shi J, Su R, Zheng D, Zhu Y, Ma X, Wang S, Li H, Sun D.   +7 more
europepmc   +1 more source

Gibbs Free Energy Calculation of Mutation in PncA and RpsA Associated With Pyrazinamide Resistance. [PDF]

Front Mol Biosci, 2020
Khan MT, Ali S, Zeb MT, Kaushik AC, Malik SI, Wei DQ.   +5 more
europepmc   +1 more source

An improved method for detection of pyrazinamide resistance in Mycobacterium tuberculosis

International Journal of Mycobacteriology, 2012
Amani Alnimr, Timothy D McHugh, Stephen H Gillespie   +2 more
openaire   +3 more sources

Enhancing diagnostic efficiency of pyrazinamide resistance in <i>Mycobacterium tuberculosis</i> via modified MGIT assay and genotypic correlation. [PDF]

Curr Res Microb Sci
Rajendran A, Refaya AK, Subramanyam B, Karunaianantham R, RaviKumar D, Haribabu H, Gopalaswamy R, Golla R, Senthildevi V, Gomathi NS, Shanmugam S, Palaniyandi K.   +11 more
europepmc   +1 more source

High prevalence of phenotypic pyrazinamide resistance and its association with pncA gene mutations in Mycobacterium tuberculosis isolates from Uganda. [PDF]

PLoS One, 2020
Naluyange R, Mboowa G, Komakech K, Semugenze D, Kateete DP, Ssengooba W.   +5 more
europepmc   +1 more source

Comprehensive evaluation of the MeltPro MTB/PZA assay for prediction of pyrazinamide resistance in multidrug-resistant tuberculosis. [PDF]

Microbiol Spectr
He G, Tu C, Zhu Y, Zheng Q, Zhou Q, Zhou W, Huang O, Chen B, Liu Z, Xu Y, Jiang X.   +10 more
europepmc   +1 more source