Results 111 to 120 of about 14,172 (227)

Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT [PDF]

, 2015
CITATION: Whitfield, M. G. et al. 2015. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT.
Birkness, Kris, Morlock, Glenn, Morlock, Glenm, Willby, Melisa, Whitfield, Michael G., Posey, James E., Mercante, Alexandra, Hughes, Kelsey, Van Rie, Annelies, Streicher, Elizabeth M., Sampson, Samantha L., Sirgel, Frik A., Van Helden, Paul D., Warren, Robin M.   +13 more
core   +1 more source

Drug susceptibility testing and line probe assay of first-line anti-tuberculosis drugs among presumptive tuberculosis patients attending a secondary care hospital in Bhubaneswar

Journal of Family Medicine and Primary Care
Background: Pyrazinamide (PZA) is important for identification in multi-drug-resistant tuberculosis patients before starting therapy. PZA drug susceptibility testing (DST) is essential for the management of drug-resistant and susceptible TB patients ...
Khusbu Singh, Braja S. Barik, Shritam Das, Tahziba Hussain, Bhawna Gupta, Dasarathi Das, Sanghamitra Pati   +6 more
doaj   +1 more source

Multiple drug-susceptibility screening in Mycobacterium bovis: new nucleotide polymorphisms in the embB gene among ethambutol susceptible strains

International Journal of Infectious Diseases, 2015
Objectives: Pyrazinamide-resistant Mycobacterium bovis isolates of animal origin were assessed for drug susceptibility to five antituberculosis drugs by the agar based Middlebrook 7H11 method as gold standard as well as by a simplified, dichotomous ...
Cinzia Marianelli, Federica Armas, Maria Beatrice Boniotti, Piera Mazzone, Maria Lodovica Pacciarini, Vincenzo Di Marco Lo Presti   +5 more
doaj   +1 more source

Prediction of pyrazinamide resistance in Mycobacterium tuberculosis using structure-based machine learning approaches [PDF]

Background: Pyrazinamide is one of four first-line antibiotics used to treat tuberculosis; however, antibiotic susceptibility testing for pyrazinamide is challenging.
Carter, Joshua, Walker, Timothy M, Walker, Ann, Posey, James E, Lynch, Charlotte I, Morlock, Glenn P, Peto, Timothy, Crook, Derrick, Adlard, Dylan, Fowler, Philip W, Whitfield, Michael G   +10 more
core  

Characterization of pyrazinamide and ofloxacin resistance among drug-resistant Mycobacterium tuberculosis isolates from Singapore [PDF]

, 2002
Objectives: To evaluate rapid molecular approaches for the detection of pyrazinamide (PZA) and ofloxacin resistance, by screening 100 known drug-resistant Mycobacterium tuberculosis isolates.Methods: Mycobacterium tuberculosis isolates were tested for ...
Tang, Lynn L.H., Lim, Irene H.K., Lee, Ann S.G., Yew Wong, Sin   +3 more
core   +1 more source

Cytochrome P450 2E1/Nickel-Poly(propylene imine) dendrimeric nanobiosensor for pyrazinamide - A first line TB Drug [PDF]

, 2015
>Magister Scientiae - MScThe tuberculosis (TB) disease to this day remains one of the world’s prominent killerdiseases. Pyrazinamide (PZA) is one of the most commonly prescribed anti- tuberculosis (anti-TB) drugs due to its ability to significantly ...
Zosiwe, Mlandeli Siphelele Ernest
core   +2 more sources

Anti tuberculosis drug resistance in west of Iran

Journal of Global Infectious Diseases, 2014
Background and Objective: Mycobacterium tuberculosis has developed resistance to antituberculosis drugs and becoming a major and alarming public health problem in worldwide.
Parviz Mohajeri, Baharak Norozi, Sara Atashi, Abbas Farahani   +3 more
doaj   +1 more source

pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia [PDF]

, 2017
Salim Allana, Elena Shashkina, Barun Mathema, Nino Bablishvili, Nestani Tukvadze, N. Sarita Shah, Russell R. Kempker, Henry M. Blumberg, Pravi Moodley, Koleka Mlisana, James C.M. Brust, Neel R. Gandhi   +11 more
openalex   +1 more source

A comparison of various measures of sensitivity of M.tuberculosis to pyrazinamide [PDF]

, 1970
A test, employing Löwenstein-Jensen medium acidified with hydrochloric acid to a preinspissation pH of 4.80-4.85, is described for determining the sensitivity to pyrazinamide of strains of M. tuberculosis.
Nair, N G K, Subbammal, S, Radhakrishna, S, Tripathy, S P, Mitchison, D A   +4 more
core   +1 more source

Prevalence, Transmission and Genetic Diversity of Pyrazinamide Resistance Among Multidrug-Resistant Mycobacterium tuberculosis Isolates in Hunan, China [PDF]

Binbin Liu,1,* Pan Su,1,* Peilei Hu,1,* Mi Yan,1 Wenbin Li,1 Songlin Yi,1 Zhenhua Chen,1 Xiaoping Zhang,1 Jingwei Guo,1 Xiaojie Wan,1 Jue Wang,1 Daofang Gong,1 Hua Bai,1 Kanglin Wan,2 Haican Liu,2 Guilian Li,2 Yunhong Tan1 1Clinical ...
Yan M, Liu H, Li G, Yi S, Wan X, Wang J, Li W, Gong D, Guo J, Su P, Chen Z, Zhang X, Tan Y, Wan K, Liu B, Bai H, Hu P   +16 more
core