Results 101 to 110 of about 2,204,307 (197)

Characterization of isoniazid resistance and genetic mutations in isoniazid-resistant and rifampicin-susceptible Mycobacterium tuberculosis in China

Infectious Medicine
Background: Patients with tuberculosis resistant to isoniazid but susceptible to rifampicin (Hr-Rs TB) remain a neglected demographic, despite a high disease burden and poor outcomes of these patients.
Dongxin Liu, Bing Zhao, Yang Zheng, Xichao Ou, Shengfen Wang, Yang Zhou, Yuanyuan Song, Hui Xia, Qiang Wei, YanLin Zhao   +9 more
doaj   +1 more source

Draft genome sequence of Mycobacterium tuberculosis strain B9741 of Beijing B0/W lineage from HIV positive patient from Siberia

Genomics Data, 2016
We report a draft genome sequence of Mycobacterium tuberculosis strain B9741 belonging to Beijing B0/W lineage isolated from a HIV patient from Siberia, Russia.
K.V. Shur, M.V. Zaychikova, N.E. Mikheecheva, K.M. Klimina, O.B. Bekker, S.N. Zhdanova, O.B. Ogarkov, V.N. Danilenko   +7 more
doaj   +1 more source

Plasma drug activity assay for treatment optimization in tuberculosis patients [PDF]

, 2011
Item does not contain fulltextLow antituberculosis (TB) drug levels are common, but their clinical significance remains unclear, and methods of measurement are resource intensive.
Scott K. Heysell, Mpagama, S., Kibiki, Gibson S, Houpt, Eric R, Mwaigwisya, S., Heysell, Scott K, Ndusilo, Norah, Pholwat, Suporn, Mwaigwisya, Solomon, Kibiki, G.S., Solomon Mwaigwisya, Suporn Pholwat, Jean Gratz, Mtabho, C., Aarnoutse, R.E., Stellah Mpagama, Heysell, S.K., Rob E. Aarnoutse, Charles Mtabho, Gratz, J., Mpagama, Stellah, Norah Ndusilo, Gratz, Jean, Houpt, E.R., Gibson S. Kibiki, Eric R. Houpt, Mtabho, Charles, Aarnoutse, Rob E, Ndusilo, N., Pholwat, S.   +29 more
core   +1 more source

Multiple drug-susceptibility screening in Mycobacterium bovis: new nucleotide polymorphisms in the embB gene among ethambutol susceptible strains

International Journal of Infectious Diseases, 2015
Objectives: Pyrazinamide-resistant Mycobacterium bovis isolates of animal origin were assessed for drug susceptibility to five antituberculosis drugs by the agar based Middlebrook 7H11 method as gold standard as well as by a simplified, dichotomous ...
Cinzia Marianelli, Federica Armas, Maria Beatrice Boniotti, Piera Mazzone, Maria Lodovica Pacciarini, Vincenzo Di Marco Lo Presti   +5 more
doaj   +1 more source

A new rapid and simple colorimetric method to detect pyrazinamide resistance in Mycobacterium tuberculosis using nicotinamide

, 2006
OBJECTIVES: The purpose of this study was to develop and assess a rapid method for pyrazinamide resistance detection in Mycobacterium tuberculosis using nicotinamide in a colorimetric resazurin assay. METHODS: We have tested M.
Portaels, Françoise, Martin, A., Palomino, J. C., Takiff, H., Portaels, F., Palomino, Juan Carlos, Vandamme, Peter, Swings, J., Vandamme, P., Martin, Anandi, Takiff, Howard, Swings, Jean   +11 more
core   +1 more source

Drug susceptibility testing and line probe assay of first-line anti-tuberculosis drugs among presumptive tuberculosis patients attending a secondary care hospital in Bhubaneswar

Journal of Family Medicine and Primary Care
Background: Pyrazinamide (PZA) is important for identification in multi-drug-resistant tuberculosis patients before starting therapy. PZA drug susceptibility testing (DST) is essential for the management of drug-resistant and susceptible TB patients ...
Khusbu Singh, Braja S. Barik, Shritam Das, Tahziba Hussain, Bhawna Gupta, Dasarathi Das, Sanghamitra Pati   +6 more
doaj   +1 more source

Pyrazinamide Resistance Assays and Two-Month Sputum Culture Status in Patients with Multidrug-Resistant Tuberculosis

, 2016
Phenotypic drug susceptibility testing is the current gold standard for detecting Mycobacterium tuberculosis susceptibility to antituberculous drugs.
Contreras, Carmen C, Calderon, Roger, Murray, Megan B, Huang, Chuan-Chin, Yataco, Rosa M., Zhang, Zibiao, Mitnick, Carole D., Velásquez, Gustavo E., Becerra, Mercedes C, Galea, Jerome T, Lecca, Leonid   +10 more
core   +1 more source

Population pharmacokinetics and pharmacokinetic-pharmacodyamic modeling of antitubercular drugs [PDF]

, 2013
Includes abstract.Includes bibliographical references.The pharmacokinetics of rifampicin, isoniazid, pyrazinamide and ethambutol in 78 patients with tuberculosis were described using non-linear mixed effects modeling.
Chigutsa, Emmanuel
core   +1 more source

Anti tuberculosis drug resistance in west of Iran

Journal of Global Infectious Diseases, 2014
Background and Objective: Mycobacterium tuberculosis has developed resistance to antituberculosis drugs and becoming a major and alarming public health problem in worldwide.
Parviz Mohajeri, Baharak Norozi, Sara Atashi, Abbas Farahani   +3 more
doaj   +1 more source

Supranational surveillance of antimicrobial resistance: The legacy of the last decade and proposals for the future

, 2010
Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat. A decade ago, several supranational surveillance initiatives were introduced. Few of them are still ongoing, and only one features
CORNAGLIA, Giuseppe, Giske CG, European Study Group on Antimicrobial Resistance Surveillance   +2 more
core   +1 more source