Results 81 to 90 of about 12,743 (165)

Draft genome sequence of Mycobacterium tuberculosis strain B9741 of Beijing B0/W lineage from HIV positive patient from Siberia

Genomics Data, 2016
We report a draft genome sequence of Mycobacterium tuberculosis strain B9741 belonging to Beijing B0/W lineage isolated from a HIV patient from Siberia, Russia.
K.V. Shur, M.V. Zaychikova, N.E. Mikheecheva, K.M. Klimina, O.B. Bekker, S.N. Zhdanova, O.B. Ogarkov, V.N. Danilenko   +7 more
doaj   +1 more source

Characterization of isoniazid resistance and genetic mutations in isoniazid-resistant and rifampicin-susceptible Mycobacterium tuberculosis in China

Infectious Medicine
Background: Patients with tuberculosis resistant to isoniazid but susceptible to rifampicin (Hr-Rs TB) remain a neglected demographic, despite a high disease burden and poor outcomes of these patients.
Dongxin Liu, Bing Zhao, Yang Zheng, Xichao Ou, Shengfen Wang, Yang Zhou, Yuanyuan Song, Hui Xia, Qiang Wei, YanLin Zhao   +9 more
doaj   +1 more source

A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance

BMC Genomics, 2017
Background Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment regimes.
Patricia Sheen, David Requena, Eduardo Gushiken, Robert H. Gilman, Ricardo Antiparra, Bryan Lucero, Pilar Lizárraga, Basilio Cieza, Elisa Roncal, Louis Grandjean, Arnab Pain, Ruth McNerney, Taane G. Clark, David Moore, Mirko Zimic   +14 more
doaj   +1 more source

Drug susceptibility testing and line probe assay of first-line anti-tuberculosis drugs among presumptive tuberculosis patients attending a secondary care hospital in Bhubaneswar

Journal of Family Medicine and Primary Care
Background: Pyrazinamide (PZA) is important for identification in multi-drug-resistant tuberculosis patients before starting therapy. PZA drug susceptibility testing (DST) is essential for the management of drug-resistant and susceptible TB patients ...
Khusbu Singh, Braja S. Barik, Shritam Das, Tahziba Hussain, Bhawna Gupta, Dasarathi Das, Sanghamitra Pati   +6 more
doaj   +1 more source

Multiple drug-susceptibility screening in Mycobacterium bovis: new nucleotide polymorphisms in the embB gene among ethambutol susceptible strains

International Journal of Infectious Diseases, 2015
Objectives: Pyrazinamide-resistant Mycobacterium bovis isolates of animal origin were assessed for drug susceptibility to five antituberculosis drugs by the agar based Middlebrook 7H11 method as gold standard as well as by a simplified, dichotomous ...
Cinzia Marianelli, Federica Armas, Maria Beatrice Boniotti, Piera Mazzone, Maria Lodovica Pacciarini, Vincenzo Di Marco Lo Presti   +5 more
doaj   +1 more source

Anti tuberculosis drug resistance in west of Iran

Journal of Global Infectious Diseases, 2014
Background and Objective: Mycobacterium tuberculosis has developed resistance to antituberculosis drugs and becoming a major and alarming public health problem in worldwide.
Parviz Mohajeri, Baharak Norozi, Sara Atashi, Abbas Farahani   +3 more
doaj   +1 more source

Pyrazinamide resistance in Mycobacterium tuberculosis arises after rifampicin and fluoroquinolone resistance.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (TB) constitute a major public health concern.To determine the timing of pncA mutations that confer pyrazinamide (PZA) resistance in relation to mutations conferring resistance to isoniazid (INH) and rifampicin (RMP).Isolates from two major urban ...
A. K. Alame-Emane, P. Xu, C. Pierre-Audigier, V. Cadet-Daniel, X. Shen, M. Sraouia, J. F. Djoba Siawaya, H. Takiff, Q. Gao, B Gicquel   +9 more
openaire   +3 more sources

Detection of Mutations in pncA in Mycobacterium tuberculosis Clinical Isolates from Nepal in Association with Pyrazinamide Resistance. [PDF]

Curr Issues Mol Biol, 2022
Shrestha D, Maharjan B, Thapa J, Akapelwa ML, Bwalya P, Chizimu JY, Nakajima C, Suzuki Y.   +7 more
europepmc   +1 more source

Quantitative ¹H Nuclear Magnetic Resonance Assay for the Rapid Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis from Sputum Samples. [PDF]

J Clin Microbiol, 2023
Lopez JM, Zimic M, Vallejos K, Sevilla D, Quispe-Carbajal M, Roncal E, Rodríguez J, Rodríguez J, Antiparra R, Arteaga H, Gilman RH, Maruenda H, Sheen P.   +12 more
europepmc   +1 more source

Correction: Immunological detection of pyrazine-2-carboxylic acid for the detection of pyrazinamide resistance in Mycobacterium tuberculosis. [PDF]

PLoS One, 2021
Florentini EA, Angulo N, Gilman RH, Alcántara R, Roncal E, Antiparra R, Toscano E, Vallejos K, Kirwan DE, Zimic M, Sheen P.   +10 more
europepmc   +1 more source