Results 1 to 10 of about 64,409 (320)
Molecules, 2022 Pyrazole has been recognized as a pharmacologically important privileged scaffold whose derivatives produce almost all types of pharmacological activities and have attracted much attention in the last decades. Of the various pyrazole derivatives reported
Mohammed I. El-Gamal +3 more
doaj +1 more source
Crystals, 2023 The pyrazole-pyridin-2-amine, as a tridentate pyrazole ligand, and its neutral Co(II)/pyrazole complex were prepared using a direct method with a high yield.
Mohamed El Boutaybi +12 more
doaj +1 more source
Crystals, 2023 Prior to 2021, 4-bromo-1H-pyrazole (published in 1999) was the only structurally characterized 4-halogenated-1H-pyrazole in the Cambridge Crystallographic Data Center (CCDC).
Kelly L. Rue +4 more
doaj +1 more source
Synthesis and SAR studies of pyrazole-3-carboxamides and -3-carbonyl thioureides including chiral moiety: Novel candidates as antibacterial agents [PDF]
Journal of the Serbian Chemical Society, 2018 A series of tetrasubstituted pyrazole-3-carboxamides (3a–c) and pyrazole- 3-carbonyl thioureides (6a–c) were synthesized and their structures characterized by IR, NMR and elemental analysis.
Bildirici Ishak +3 more
doaj +1 more source
Novel Pyrazole Derivatives Having Mono/Di Chiral Centered Group as Organocatalyst for Henry Reaction
Macedonian Journal of Chemistry and Chemical Engineering, 2020 The chiral substituted pyrazole-3-carboxamides (4a-c), pyrazole-3-carboxylates (5a-c), pyrazole-3-thioureides (7a-c) and pyrazole-3,4-dicarboxamides (10a-c) were prepared via the pyrazolo-3-chlorocarbonyl 2, pyrazolo-3,4-dicarboxy methyl ester 3 with ...
Adnan Çetin +2 more
doaj +1 more source
Crystal and molecular structure of 4-fluoro-1H-pyrazole at 150 K
Acta Crystallographica Section E: Crystallographic Communications, 2023 Only two 4-halo-1H-pyrazole crystal structures are known to date (chloro and bromo, the structure of 4-iodo-1H-pyrazole has not been reported yet). The triclinic structure of 4-fluoro-1H-pyrazole, C3H3FN2 (P\overline{1}), reported here is not isomorphous
Basil M. Ahmed +2 more
doaj +1 more source
Enantioselective Addition of Pyrazoles to Dienes** [PDF]
Angewandte Chemie International Edition, 2021 AbstractWe report the first enantioselective addition of pyrazoles to 1,3‐dienes. Secondary and tertiary allylic pyrazoles can be generated with excellent regioselectivity. Mechanistic studies support a pathway distinct from previous hydroaminations: a Pd0‐catalyzed ligand‐to‐ligand hydrogen transfer (LLHT).
Alexander Y. Jiu +4 more
openaire +5 more sources
Carbamidine-substituted Pyrazoles [PDF]
Nature, 1951 THE ease with which 1-substituted pyrazoles may be converted into the free imino compounds varies with the nature of the 1-substituent and the reacting substance. Thus, 1,3,5-trimethyl pyrazole may be nitrated1 and 1-phenyl pyrazole reduced to the pyrazoline2 without loss of the N-methyl or N-phenyl groups respectively.
J. Reilly, C. M. B. Murphy, F. L. Scott
openaire +3 more sources
Two CuII complexes of 3,4,5-trimethyl-1H-pyrazole
Acta Crystallographica Section E: Crystallographic Communications, 2018 The crystal structure of complexes of 3,4,5-trimethyl-1H-pyrazole with CuCl2·2H2O and Cu(NO3)2·2.5H2O are presented, namely di-μ-chlorido-bis[chloridobis(3,4,5-trimethyl-1H-pyrazole-κN2)copper(II)], [Cu2Cl4(C6H10N2)4] (1) and aquatetrakis(3,4,5-trimethyl-
Collin J. Vincent +2 more
doaj +1 more source
Frontiers in Pharmacology, 2020 A series of trifluoromethylated pyrazole thiosemicarbazone, trifluromethylated pyrazole isothiosemicarbazone, and trifluoromethylated pyrazole 2-amino-1,3,4-thiadiazole hybrids were synthesized and evaluated in vitro against the promastigote form of ...
Jeniffer do Nascimento Ascencio Camargo +7 more
doaj +1 more source