Results 61 to 70 of about 4,108 (208)

N1-benzenesulfonyl-2-pyrazoline hybrids in neurological disorders [PDF]

A novel series of 1,3,5-trisubstituted-2-pyrazolines (5a-5t) was prepared via Claisen Schmidt condensation, followed by heterocyclization with hydrazine hydrate, substitution of N1 hydrogen of 2-pyrazoline nucleus with 4-chlorobenzenesulfonylchloride ...
Paliwal, Sarvesh, Saraf, Shailendra K., Tripathi, Avinash C., Upadhyay, Savita   +3 more
core   +1 more source

Synthetic Methods for Four‐Membered Carbocycles Bearing Emerging Fluorinated Motifs

Chemistry – An Asian Journal, Volume 20, Issue 23, December 2, 2025.
In this review, we provide an overview of four‐membered carbocycles with “emerging” fluorine‐containing motifs, including mono, di, and trifluoromethyl groups, sulfur‐ and other hetero atom‐linked substituents. Such molecular structures are well utilized as one of the recent trends in drug design. Recent progress of cyclobutane‐based polycyclic systems,
Hikaru Yanai, Shoki Hoshikawa, Kentaro Kawai, Takashi Matsumoto   +3 more
wiley   +1 more source

SASH: Student Academic Showcase and Honors 2018 [PDF]

, 2017
A celebration of scholarship and creative activities for undergraduate and graduate students held in April, 2018 at the Roger Williams University campus in Bristol, Rhode ...
Roger Williams University
core   +2 more sources

An overview of 2-Styrylchromones: natural occurrence, synthesis, reactivity and biological properties [PDF]

, 2017
2-Styrylchromones are a small class of oxygen-containing heterocycles. Despite their sparse occurrence in nature, several synthetic approaches have been developed in order to synthesize a large variety of derivatives, possessing different substituents ...
Alonso, Ayyangar, Aziz, Baker, Baptista, Barros, Barros, Bennett, Berar, Bhattacharyya, Cavaleiro, Chaniad, Cheema, Clarke, Conti, Dean, Desideri, Desideri, Dhoubhadel, Doria, Elkashef, Fernandes, Fernandes, Ferreira, Filipe, Fuchigami, Fuchigami, Gaggad, Gaspar, Gerwick, Gerwick, Goel, Gomes, Gomes, Gomes, Gomes, Gomes, Gulati, Gupta, Gupta, Helibron, Hercouet, Jain, Jung, Karton, Kelkar, Keri, Kumar, Kumar, Königs, Lee, Letcher, Letcher, Letcher, Lin, Mahal, Makrandi, Makrandi, Marinho, Marini-Bettòlo, Marona, McGarry, Momin, Momin, Momoi, Mustafa, Nam, Nikam, Obrecht, Ono, Paparao, Patoilo, Patoilo, Pawar, Peixoto, Pereira, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Price, Reddy, Reddy, Robinson, Santos, Santos, Santos, Santos, Santos, Saraf, Schonberg, Sharma, Sharma, Shaw, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Singhi, Sousa, Sousa, Takamatsu, Talhi, Tawfik, Yang, Yang, Yokoe, Yoon, Zammattio, Zammattio, Zammattio   +122 more
core   +1 more source

Applications of QSPR and Machine Learning in Molecular Photonics

Advanced Optical Materials, Volume 13, Issue 33, November 25, 2025.
Quantitative structureproperty relationships (QSPR) and machine learning (ML) are transforming photochemistry by enabling pre‐synthetic screening of photoactive molecules. This review outlines advances in data‐driven discovery of optical materials and functional dyes, identifies effective descriptors and models for photophysical processes, and provides
Andrey A. Buglak, Platon P. Chebotaev, Mikhail A. Filatov   +2 more
wiley   +1 more source

Radical Fluoroalkylation Reactions [PDF]

, 2018
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized ...
Barata Vallejo, Sebastian, Cooke, María Victoria, Postigo, A.   +2 more
core   +1 more source

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, Volume 14, Issue 11, November 2025.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

Synthesis and in Vitro Antimicrobial Activity of Some Pyrazolyl-1-carboxamide Derivatives

Molecules, 2011
A series of 3,5-disubstituted pyrazole-1-carboxamides were obtained by treatment of chalcones with semicarbazide hydrochloride in dioxane containing sodium acetate/acetic acid as a buffer solution.
Essam Mohamed Sharshira, Nagwa Mohamed Mahrous Hamada   +1 more
doaj   +1 more source

Ferrocén-szubsztituált heterociklusok és származékaik szintézise, szerkezetigazolása és komplex spektroszkópiai vizsgálata = Synthesis, structure determination and complex spectroscopic study of ferrocene-substituted heterocycles and their derivatives [PDF]

, 2007
Új, mono- és poliheterociklusokkal egyszeresen és többszörösen szubsztituált ferrocénszármazékokat állítottunk elő. Szerkezetüket komplex nagyműszeres vizsgálatokkal (IR, MS, röntgendiffrakció, multinukleáris NMR) derítettük fel.
Csámpai, Antal, Perjési, Pál, Sohár, Pál, Túrós, György István, Zsoldosné dr. Mády, Virág   +4 more
core  

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima, Lassaletta, José M., Matador Martínez, Esteban, Monge Fernández, David, Retamosa Hernández, María Gracia   +4 more
core   +1 more source