Results 71 to 80 of about 4,108 (208)

Small Molecular Dibenzochalcogenophenes as Potent Organic Emitters

Chemistry – A European Journal, Volume 31, Issue 56, October 8, 2025.
This review compiles recent achievements and applications of purely organic small luminescent DBC. We present frequently employed functionalities and design strategies, accomplishing room temperature phosphorescence (RTP). In addition, we discuss the challenges for luminescent selenium and tellurium derivatives as well as the influence of commercial ...
Marco Schmiedtchen, Lea Höfmann, Jan Balszuweit, Jens Voskuhl   +3 more
wiley   +1 more source

λ5-Phosphorus-Containing α-Diazo Compounds (PCDCs): a valuable tool for accessing phosphorus-functionalized molecules [PDF]

, 2016
The compounds characterized by the presence of a λ5-phosphorus functionality at the α-position with respect to the diazo moiety, here referred to as λ5-phosphorus-containing α-diazo compounds (PCDCs), represent a vast class of extremely versatile ...
Marinozzi, Maura, Pertusati, Fabrizio, Serpi, Michaela   +2 more
core   +2 more sources

From Design to Outcome: The Role of Bi‐ and Multifunctional Ligands in Modern Therapeutics

Advanced Therapeutics, Volume 8, Issue 10, October 2025.
This review highlights the innovative use of bi‐ and multifunctional ligands for precision therapeutics. From strategic linker design to bioorthogonal conjugation and nanoscaffold integration, these approaches enable precise targeting, high‐resolution receptor mapping, and enhanced drug delivery.
Célia Bouacha, Séverine Denoyelle, Sonia Cantel   +2 more
wiley   +1 more source

A Study of Antioxidant Properties and a Pharmacokinetic Investigation of Chalcones and Pyrazolines

Orbital: The Electronic Journal of Chemistry
Antioxidant compounds are widely studied in the literature because they minimize oxidative damage in biological processes. In this context, chalcones and pyrazolines are considered prototype compounds for this purpose. This study describes the synthesis
André Luis Kerek, Larissa Kozan , Gabrielle Schamne Fonseca , Bianca Sartori dos Santos , Raphaela Pereira Guaringue , Larissa Sens, Barbara Celânia Fiorin   +6 more
doaj   +1 more source

The Azidofunctionalization of Alkenes

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

Synthesis, quantitative structure–property relationship study of novel fluorescence active 2-pyrazolines and application [PDF]

Royal Society Open Science, 2018
A variety of fluorescence-active fluorinated pyrazolines 13–33 was synthesized in good yields through cyclocondensation reaction of propenones 1–9 with aryl hydrazines 10–12.
Adel S. Girgis, Altaf H. Basta, Houssni El-Saied, Mohamed A. Mohamed, Ahmad H. Bedair, Ahmad S. Salim   +5 more
doaj   +1 more source

Sintesis Pirazolin dari Kalkon 3-kloro Inti Naftalen dan Uji Aktivitasnya sebagai Antibakteri [PDF]

, 2014
Pyrazolines have been reported to possess many of interesting biological activities such as antimicrobial, antidepressant, antitumor, antioxidant, antiinflammatory, anticancer and anticonvulsant activity .
Jasril, J. (Jasril), Puspita, A. (Ary), Teruna, H. Y. (Hilwan)   +2 more
core  

X-ray Structure of a (o-ga/acto-Pentaacetoxypentyl)pyrazoline [PDF]

, 1989
1-(3,5-Dimethyl-3-nitro-1-pyrazolin-4-yl)­ penta-0-acetyl-o-galacto-pentitol, e20H29N 3012, Mr= 503·5, orthorhombic, P21212¡, a= 14·471 (9), b = 14·518 (3), e= 12·028 (2) A, V= 2527·0 (1·7) A3, z = 4, Dx = 1·323 Mg m- 3, .A(Mo Ka)= 0·7107 A, J.
Conde Amiano, Alejandro, Conde Amiano, Clara Francisca   +1 more
core   +1 more source

AI/ML‐Driven DPP‐4 Inhibitor Predictor (d4p_v1) for Enhanced Type 2 Diabetes Mellitus Management: Insights Into Chemical Space, Fingerprints, and Electrostatic Potential Maps

Archiv der Pharmazie, Volume 358, Issue 9, September 2025.
Favourable and unfavourable fingerprints governing dipeptidyl peptidase‐4 (DPP‐4) inhibition are identified using fragment‐based analysis, validating key fingerprints through HOMO–LUMO gap analysis and electrostatic potential maps. AI/ML‐driven DPP‐4 predictor, an online cheminformatics tool for efficient DPP‐4 inhibitor screening, is reported ...
Anu Manhas, Ritam Dutta, Stefano Piotto, Sk. Abdul Amin   +3 more
wiley   +1 more source

Molecular mechanism of ATP‐binding cassette transporter‐mediated insecticide resistance

New Plant Protection, Volume 2, Issue 3, September 2025.
Advances in functional genomics (RNAi and CRISPR/Cas9) and artificial intelligence‐driven structure prediction (e.g., AlphaFold) are elucidating how ATP‐binding cassette transporters mediate insecticide resistance to both synthetic chemicals and Bacillus thuringiensis toxins.
Yuntong Lv, Pengcheng Wang, Zihan Wei, Xueqing Yang   +3 more
wiley   +1 more source