Results 101 to 110 of about 20,827 (302)

Reactions of 1,2,4‐Oxadiazole[4,5‐a]piridinium Salts with Alcohols: the Synthesis of Alkoxybutadienyl 1,2,4‐Oxadiazoles

ChemistryOpen, 2020
1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola, Dr. Marco Leusciatti, Prof. Dr. Paolo Quadrelli   +2 more
doaj   +1 more source

One-pot Synthesis of 6-Aza-chromone Derivatives Through Cascade Carbonylation-Sonogashira-Cyclization

Scientific Reports, 2017
We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction.
Gang Cheng, Yingbei Qi, Xiaoqian Zhou, Rong Sheng, Yong-Zhou Hu, Youhong Hu   +5 more
doaj   +1 more source

Study on the Lewis Acid-promoted Aza-Diels - Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones [PDF]

, 2008
trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels – Alder reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro ...
Habuš, Ivan, Margetić, Davor, Molčanov, Krešimir, Poljak, Tanja   +3 more
core   +1 more source

Innovative solutions to sticky situations: Antiadhesive strategies for treating bacterial infections [PDF]

, 2016
Bacterial adherence to host tissue is an essential process in pathogenesis, necessary for invasion and colonization and often required for the efficient delivery of toxins and other bacterial effectors.
Aberg, Abgottspon, Allen, Allison, Alves, Aminov, Anderson, Andersson, Andersson, Andreini, Anthouard, Arnqvist, Aronson, Arrecubieta, Ashkar, Autar, Avorn, Bajolet-Laudinat, Barbosa-Cesnik, Barczak, Barnhart, Barnhart, Barocchi, Blanco, Bouckaert, Bouckaert, Boukerb, Boyle, Branderhorst, Breimer, Breimer, Briles, Britton, Brown, Buffie, Candela, Cecioni, Cecioni, Cegelski, Chabre, Chagnot, Chang, Chapman, Chemani, Chen, Chen, Chorell, Choudhury, Cioci, Clatworthy, Cole, Coppa, Cossart, Costerton, Cozens, Cusumano, Dam, Delnay, DePas, Dethlefsen, Diggle, Dodson, Donlan, Dramsi, Ebersbach, Eto, Evans, Fagon, Falugi, Ferreira, Findlow, Finlay, Finlay, Fischetti, Flores-Mireles, Foo, Ford, Foxman, Frankel, Furiga, Gao, Garcia-Medina, Gaudreau, Geibel, Gellatly, Ghosh, Giugliano, Glick, Goller, Gouin, Goyal, Greco, Greene, Griebling, Guiton, Guiton, Guiton, Guiton, Gustafsson, Guttilla, Haataja, Hakkarainen, Hammar, Hammer, Hammer, Hampton, Han, Han, Hansson, Hart, Haslam, Hauck, Hawley, Hentzer, Hernell, Hofmann, Hollenbeck, Horvath, Howell, Hung, Hung, Hur, Hur, Idanpaan-Heikkila, Isberg, Jacob-Dubuisson, Jay, Jiang, Jones, Jones, Joosten, Juliano, Kadam, Kadam, Kai-Larsen, Kang, Kang, Kauppi, Keeney, Kelly, Kierek-Pearson, Kim, Kim, Kim, Kisiela, Kleeb, Klein, Klein, Klein, Kline, Kontiokari, Konto-Ghiorghi, Korhonen, Kozel, Krachler, Krachler, Krachler, Kruger, Kummerfeldt, Langermann, Langermann, Lanne, Lanne, Larsson, Lebeaux, Lee, Lee, Lee, Lehner, Lewis, Li, Liu, Liukkonen, Lo, Loveless, Lund, Lyczak, Ma, Mack, Mamo, Mandlik, Manefield, Mapingire, Maresso, Maresso, Maresso, Marotte, Marraffini, Mayville, Mazmanian, Mazmanian, Menard, Migone, Migone, Miller, Mitchell, Morrow, Morvan, Munera, Murray, Mysore, Nallapareddy, Neeser, Nenninger, Nenninger, Newburg, Nicolle, Nielsen, Nielsen, Nielubowicz, Nishikawa, Nishikawa, Nishiyama, Nuccio, O'Toole, Ofek, Ofek, Oh, Oh, Oh, Ohlsson, Ohlsson, Okuda, Olsen, Oppong, Orndorff, Otsuka, Paganelli, Pak, Palumbi, Pang, Park, Parker, Patel, Perret, Pertici, Peychl, Phan, Piatek, Pieters, Pinkner, Prabu, Proft, Puorger, Pusztai, Raghunathan, Rapsinski, Rasko, Remaut, Remaut, Rivera, Roberts, Robinson, Rosen, Ruiz-Palacios, Saeki, Saldana, Salminen, Sauer, Sauer, Savar, Scharenberg, Schlager, Schneewind, Schroten, Schulte, Schwardt, Scott, Sekirov, Serruto, Sheth, Shu, Signoretto, Smith, Song, Staat, Stamm, Starkey, Steadman, Stromqvist, Su, Svensson, Thanassi, Therrien, Thomas, Tielker, Toivanen, Ton-That, Ton-That, Ton-That, Ton-That, Turgeon, Ubeda, Van Houdt, Vangay, Vengadesan, Volkan, Walsh, Wang, Wang, Wellens, Whittaker, Wilson, Wolinsky, Wu, Wu, Wurpel, Xiao, Yamaguti-Sasaki, Yamanaka, Yanagawa, Younson, Zhang, Zhang, Zinger-Yosovich   +314 more
core   +2 more sources

Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones

Drug Design, Development and Therapy, 2017
Galal Elgemeie,1 Farag Altalbawy,2,3 Mohammed Alfaidi,3 Rania Azab,2,4 Atef Hassan5 1Department of Chemistry, Faculty of Science, Helwan University, Helwan, 2National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt ...
Elgemeie G, Altalbawy F, Alfaidi M, Azab R, Hassan A   +4 more
doaj  

Kristallstruktur eines 2-Dimethylamino-3,3-dimethyl-4(3H)-pyridons

CHIMIA, 1982
3-Dimethylamino-2,2-dimethyl-2H-azirine (1) reacts with alkyl phenyl substituted cyclopropenones 2 in benzene at 130 °C to give a mixture of the two isomeric 4(3H)-pyridones 3 and 4, resulting from a nucleophilic attack at C(2) and C(1) of the ...
Jost H. Bieri, Roland Prewo, Heinz Heimgartner   +2 more
doaj   +1 more source

RhIII-Catalyzed Synthesis of Isoquinolones and 2-Pyridones via Annulation of N-Methoxyamides and Nitroalkenes.

Annalen der Pharmacie, 2018
The Rh(III)-catalyzed synthesis of 4-substituted isoquinolones and 2-pyridones by the annulation of N-methoxyamides and nitroalkenes has been developed. Both aliphatic and aromatic nitroalkenes were effective inputs.
T. Potter, Yuantao Li, M. Ward, J. Ellman   +3 more
semanticscholar   +1 more source

Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

Molecules, 2012
Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao, Zhongjun Li, Renna Luo, Gaoyun Hu, Qi Hou, Zhiqi Lao, Lingling Xuan, Jinye Bai, Xiangbao Meng, Qinghua Lou   +9 more
doaj   +1 more source

Electrocyclic Ring‐Opening of 1,2,4‐Oxadiazole[4,5‐a]piridinium Chloride: a New Route to 1,2,4‐Oxadiazole Dienamino Compounds

ChemistryOpen, 2019
1,2,4‐Oxadiazole[4,5‐a]piridinium chloride adds nucleophiles to undergo electrocyclic ring opening affording 1,2,4‐oxadiazole dienamino derivatives. These pyridinium salts represent a special class of Zincke salts that are prone to rearrange when treated
Dr. Stefano Carella, Dr. Misal Giuseppe Memeo, Prof. Paolo Quadrelli   +2 more
doaj   +1 more source

A flexible radical approach to 5-substituted 4,5-dihydro-3H-pyrido[4,3-b]azepin-2-ones. Some mechanistic observations on the radical cyclisation-aromatisation process

, 2012
International audienceVariously substituted novel dihydropyridoazepinones have been prepared by an intermolecular radical addition followed by a radical cyclisation on a pyridine ring. The latter process involved the use of a combination of two different
Botez, I., Petit, Laurent, Tizot, A., Zard, Samir,   +3 more
core   +3 more sources