Arylxanthones and arylacridones: a synthetic overview [PDF]
Arylxanthones and arylacridones although not yet found in nature are becoming an important group of heterocyclic compounds due to their promising biological activities.
Pinto, Diana +3 more
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Dakin-West Trick in the Design of Novel 2-Alkyl(aralkyl) Derivatives of Oxazolo[3,2-a]pyridines
A series of previously unavailable derivatives of 2-alkyl- and 2-benzylderivatives of oxazolo[3,2-a]pyridines III were obtained via tandem ring opening and ring closure from stable mesoionic 3-acyloxazolo[3,2-a]pyridinium-2-olates I.
Eugene V. Babaev +2 more
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International audienceVariously substituted novel dihydropyridoazepinones have been prepared by an intermolecular radical addition followed by a radical cyclisation on a pyridine ring. The latter process involved the use of a combination of two different
Botez, I. +3 more
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Relative Reactivities of Acetals and Ethers under Friedel-Crafts Conditions [PDF]
Competition experiments have been performed to determine the relative reactivities of acetals and ethers toward allyltrimethylsilane in the presence of catalytic amounts of BF3 OEt2.
Dau-Schmidt +11 more
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Synthesis of 5-(substituted phenylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones from ethyl 3-oxo-2-(substituted phenylazo)butanoates, Short communication [PDF]
A new procedure for the synthesis of known azo pyridone dyes is presented. A series of 5-(substituted arylazo)-6-hydroxy-4-methyl-3-cyano-2-pyridones were prepared from ethyl 3-oxo-2-(substituted phenylazo)butanoates and cyanoacetamide in acetone using ...
GORDANA UŠĆUMLIĆ +3 more
doaj
The reaction of 4-hydroxycoumarin (1) with some primary amines 2a-h and morpholine (2i) under microwave irradiation occurred without opening of the lactone ring to give N-substituted 4-aminocoumarins 3a-i in excellent yields.
Ivo C. Ivanov, Edmont V. Stoyanov
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Design, Synthesis and Anti-HIV Integrase Evaluation of 4-Oxo-4H-quinolizine-3-carboxylic Acid Derivatives [PDF]
4-Oxo-4H-quinolizine-3-carboxylic acid derivatives bearing sulfamido, carboxylamido, benzimidazole and benzothiazole substituents have been designed and synthesized. The structures of these new compounds were confirmed by 1H-NMR, 13C- NMR, IR and ESI (or
Brown +12 more
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O- and N-Difluoromethylation of 2-Pyridones with Chlorodifluoromethane
Difluoromethylation of various 2-pyridones with the available industrial reagent chlorodifluoromethane (Freon-22) has been studied. Some relationships between the ratio of difluoromethylation products and the reaction conditions, as well as the presence ...
Kirill I. Petko, Andrey A. Filatov
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Positive Allosteric Modulators for mGluR2 Receptors: A Medicinal Chemistry Perspective [PDF]
Keserű, György Miklós +1 more
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Production of Insect Toxin Beauvericin From Entomopathogenic Fungi Cordyceps Militaris by Heterologous Expression of Global Regulator [PDF]
Cordyceps militaris is one of entomopathogenic fungi species that is well known to be a traditional medicine in China for decades. Although the pharmaceutical and/or toxic properties of C.
Kinoshita, H. (Hiroshi) +2 more
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