Results 41 to 50 of about 12,719 (269)
Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates [PDF]
, 2014 This tutorial review highlights the organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium/azolium enolates.
Morrill, Louis C., Smith, Andrew D.
core +1 more source
Efficient synthesis of novel thieno[3,2-b]-, [2,3-c]- and [3,2-c]pyridones by Sonogashira coupling of bromothiophenes with terminal alkynes and subsequent intramolecular C-N bond-forming reaction [PDF]
, 2013 The coupling of bromothiophenes with terminal alkynes using triethylamine or diisopropyl amine under Sonogashira conditions (PdCl2(PPh 3)2, CuI) followed by subsequent addition of amines or ammonium to the intermediate thienyl acetylenes represents a ...
Abbasi, M. S. A. +7 more
core +1 more source
Tautomerism of 4-Pyridones [PDF]
Bulletin of the Chemical Society of Japan, 1977 Abstract The tautomeric constants, Kt, of several 4-pyridones were determined by measurement of pKa values. For 2-substituted 5-methoxy-4-pyridones, the Kt values were correlated to the substituent constants σ, the equation logkt=2.98+2.93σm−6.18σo being obtained.
Hiromichi Besso +2 more
openaire +2 more sources
Synthesis and investigation of solvent effects on the ultraviolet absorption spectra of 5-substituted-4-methyl-3-cyano-6-hydroxy-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2001 A number of 5-substituted-4-methyl-3-cyano-6-hydroxy-2-pyridones from cyanoacetamide and the corresponding alkyl ethyl acetoacetates were synthesized according to modified literature procedures. The alkyl ethyl acetoacetates were obtained by the reaction
NATASA V. VALENTIC +2 more
doaj +3 more sources
CHIMIA, 2020 N-Heterocyclic carbenes (NHCs) are the ligands of choice in a large variety of transformations entailing different transition metals. However, the number and variety of chiral NHCs suitable as stereo-controlling ligands in asymmetric catalysis remains ...
Johannes Diesel, Nicolai Cramer
doaj +1 more source
Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2019 In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana +3 more
doaj +1 more source
Development of an Organoautocatalyzed Double σ‐Bond C(sp2)‐N Transamination Metathesis Reaction
Angewandte Chemie, EarlyView.Organoautocatalyzed transamination metathesis of cyclic tertiary amines is disclosed as a high‐yielding, scalable reaction that proceeds under mild, catalyst‐free conditions. It operates via a multi‐step domino reaction mechanism, where an in situ‐formed pyrrolidinium salt functions as a HBD organoautocatalyst.
Volker Klein +7 more
wiley +2 more sources
Die Acylierung von 4‐Pyridon [PDF]
Chemische Berichte, 1980 AbstractBei der Acylierung von 4‐Pyridon (1) mit aliphatischen Carbonsäure‐anhydriden und ‐chloriden oder freien Säuren in Gegenwart von Dicyclohexylcarbodiimid erhält man ausschließlich N‐Acyl‐4‐pyridone (5). Auch bei der Umsetzung von 1 mit ortho‐substituierten Benzoesäurederivaten sind nur N‐Acylierungsprodukte 8 isolierbar.
Effenberger, Franz +2 more
openaire +2 more sources
Reverse Regioselective Dicarbofunctionalization via Anti‐Michael‐Type Addition
Angewandte Chemie, EarlyView.A reverse regioselective dicarbofunctionalization of acrylamides via anti‐Michael‐type addition is reported. Various (hetero)arene nucleophiles and carbon electrophiles were incorporated in a manner opposite to conventional regioselectivity. A key feature of this reaction is the formation of an alkylpalladium intermediate, which enables the achievement
Hirotsugu Suzuki +2 more
wiley +2 more sources
SynOpen, 2021 An efficient method for the synthesis of highly substituted bicyclic pyridone derivatives containing the dithiocarbamate group is reported via a one-pot three-component reaction of 2-(alkylthio)thioazlactones, diamines, and nitroketene dithioacetal in ...
Marziyeh Saeedi +6 more
doaj +1 more source