Results 51 to 60 of about 12,719 (269)
3-Cyano-4,6-dimethyl-2-pyridone (Guareschi pyridone)
Acta Crystallographica Section E Structure Reports Online, 2004 In the crystal structure of the title compound, C8H8N2O, the molecules form centrosymmetric dimers via N—H⋯O hydrogen bonds.
Victor B. Rybakov +3 more
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Synthesis of Some New Enaminoketones, Analogous of Milrinone, 4,Pyrones and Related 4-Pyridones [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1996 Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.
Aziz Shahrisa, Salar Hemmati
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Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
Molecules, 2015 Treatment of 2,3-diaryloxirane-2,3-dicarbonitriles 1a–c with different nitrogen nucleophiles, e.g., hydrazine, methyl hydrazine, phenyl hydrazine, hydroxylamine, thiosemicarbazide, and/or 2-amino-5-phenyl-1,3,4-thiadiazole, afforded pyrazole, isoxazole ...
Mohamed E. Azab +2 more
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Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]
, 2018 Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael +8 more
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2-Pyridone: monoclinic polymorph [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 تتكون الوحدة غير المتماثلة في مركب العنوان، C(5)H(5)NO، من جزيئتين مستقلتين ولكن متطابقتين تقريبًا من 2 -بيريدون، وتمثل شكلًا متعددًا أحادي الميل من شكل أورثو- روم- بيك (P2 (1)2(1)2(1)) [Penfold (1953▶). أكتا كريست .6، 591-600 ؛ أومس وآخرون. (1984▶). Z. Kristallogr.169، 185-200 ؛ Yang & Craven (1998▶). أكتا كريست. B54، 912-920]. ترتبط الحبيبات الجزيئية
Hadi D. Arman +2 more
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Crystal structure of 2,6-dimethyl-4-pyridone hemihydrate
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound (systematic name: 2,6-dimethyl-1H-pyridin-4-one hemihydrate), C7H9NO·0.5H2O, has a single planar molecule in the asymmetric unit with the non-H atoms possessing a mean deviation from planarity of 0.021 Å.
Dalena M. Nguyen +3 more
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Enzymatic synthesis of vitamin B6 precursor [PDF]
, 2013 3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Bezbradica Dejan I. +4 more
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Pyridonderivate aus 3-Amino-2H-azirinen und Cyclopropenonen
CHIMIA, 1978 Reaction of the 3-dimethylamino-2H-azirines 1a and 1b with diphenylcyclopropenone (2a) in ether or acetonitrile leads to the 2-dimethylamino-5,6-diphenyl-4(3H)-pyridones 3a and 3b in 70 and 80% yield, respectively. The structure of these 1:1-adducts has
Stanislav Chaloupka, Heinz Heimgartner
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Recent Progress in Nitro-Promoted Direct Functionalization of Pyridones and Quinolones
Molecules, 2020 Nitro group is one of the most important functional groups in organic syntheses because its strongly electron-withdrawing ability activates the scaffold, facilitating the reaction with nucleophilic reagents or the Diels−Alder reaction.
Feiyue Hao, Nagatoshi Nishiwaki
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Chemical Cryptology of Cancer’s Histone Code [PDF]
, 2014 Somatic mutations in non-Hodgkin's lymphoma frequently activate EZH2, a protein methyltransferase responsible for H3K27 trimethylation. In this issue of Chemistry and Biology, Bradley and coworkers describe a new set of EZH2 inhibitors amenable to ...
Kulkarni, Rhushikesh A. +1 more
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