Results 51 to 60 of about 9,290 (210)

Deoxyfluorination of Phenols [PDF]

, 2011
An operationally simple ipso fluorination of phenols with a new deoxyfluorination reagent is presented.Chemistry and Chemical ...
Ritter, Tobias, Tang, Pingping, Wang, Weike   +2 more
core   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, EarlyView.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind, Shane C. Wright, Emilia Gvozdenovic, Kristina Nilsson, Kenneth L. Granberg, Michel Bouvier, Linda C. Johansson   +6 more
wiley   +1 more source

Photochemical Cycloadditions to 5,6-Dihydro-4-pyridones

CHIMIA, 1987
5,6-Dihydro-4-pyridones (3a-3c) undergo photochemical [2 + 2]-cycloaddition with olefins activated by an electron withdrawing group. Alkyl substituted double bonds could only be brought to react in the intramolecular cases 3d and 3e.
Philippe Guerry, Reinhard Neier
doaj   +1 more source

Evaluation of chemical compounds for induction of male sterility in wheat (Triticum aestivum L.) [PDF]

, 2006
The short-list of eleven chemical hybridizing agents (CHAs) showing 98% or more induction of male sterility were identified following application at the pre-meiotic stage of wheat.
Chakraborty, Kajal, Devakumar, C
core  

Waltherione C and cleomiscosin from Melochia umbellata var. Degrabrata K. (Malvaceae), biosynthetic and chemotaxonomic significance [PDF]

, 2014
Waltherione C, a 4-quinolinone secondary metabolite, and cleomiscosin have been isolated from Melochia umbellata (Malvaceae).A biosynthetic scheme incorporating the unique 4-pyridones and 4-quinolones isolated from Melochia and Waltheria spp.
Noor, Alfian, Soekamto, Nunuk H.
core   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

The FEBS Journal, EarlyView.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil, Haocheng Qianzhu, Elwy H. Abdelkader, Adarshi P. Welegedara, Josemon George, Christoph Nitsche, Thomas Huber, Gottfried Otting   +7 more
wiley   +1 more source

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections [PDF]

, 2016
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently.
Alibana-Clouser, F, Antonyuk, SV, Brasseur, G, Capper, M, Donkin, D, Dovgin, S, Dubey, J, El Bissatai, K, Esaa, F, Fishwick, CWG, Fraczek, L, Gordon, J, Hasnain, S, He, Y, Hickman, M, Hood, L, Kent, M, Kim, E, Kim, TK, Lee, P, Lorenzi, H, Lukens, AK, Lykins, J, McLeod, R, McPhillie, M, Meunieur, B, Moulton, H, Muench, S, Roberts, CW, Sanders, J, Santos, T, Verma, SK, Wang, K, Weber, CR, Weiss, L, Wheeler, K, Wirth, D, Woods, S, Zhou, Y   +38 more
core   +4 more sources

Asymmetric Negishi and Kumada Couplings

Advanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.
This review summarizes asymmetric Negishi and Kumada cross‐coupling reactions from the 1980s through 2025. It examines enantioselective and enantiospecific transformations catalyzed by nickel, palladium, and cobalt complexes , highlighting ligand design, mechanistic insights, and applications in constructing complex chiral molecules and natural ...
Rui‐Heng Wang, Aishun Ding, Ramon Rios
wiley   +1 more source

Frame‐Shifted Synthesis of Oligoheterocycles as a Platform for Molecular Design

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Modern chemistry seeks to turn the simple raw materials into complex molecules that matter in health, agriculture, and technology. Among these, oligoheterocycles stand out for their versatility, yet they are most often built by cross‐coupling reactions that often rely on expensive metal catalysts.
Kane A. C. Bastick, Caleb E. Griesbach, Ben Zhen Huang, Morgan J. Cordell, Yang (Daniel) Ou, Alán Aspuru‐Guzik, Andrei K. Yudin   +6 more
wiley   +2 more sources