Results 81 to 90 of about 20,092 (323)
Synthesis of a Pyridone ALkaloid, Cerpegin.
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Takahiko Arase, Keizo Matsuo
openaire +4 more sources
New approach to condensed pyrid-2-ones [PDF]
We wish to report a simple procedure for the preparation of 5-substituted-thienopyridin-7-ones and 7-substituted-1,6-naphthyridin-5(6H)-ones, in good yields, from the dianions of 3-methylthiophene-2-carboxylic and 2-methylnicotinic acids on treatment ...
Brun Sanchez, Eva Maria+2 more
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Multistep Reactions Initiated by Amine‐Based Organometallic Methods
The advent of C–H activation and other organometallic methodologies making use of transient directing groups or free amines themselves for the elaboration of amine substrates provides unique access to cascade‐type reactions that can generate significant molecular complexity in one pot. The pursuit of atom‐ and step‐economical pathways to access complex
Victoria D. Ho+3 more
wiley +1 more source
A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones
Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied.
Federica Arioli+5 more
doaj +1 more source
Synthesis of 4-Pyridone-3-sulfate and an improved synthesis of 3-Hydroxy-4-Pyridone [PDF]
An improved synthesis of 3-hydroxy-4-pyridone via an Elbs oxidation of 4-pyridone and isolation of 4-pyridone-3-sulfate is described.
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Study on the Lewis Acid-promoted Aza-Diels - Alder Reaction of Azetidin-2-one-tethered Imines with Siloxydienes in the Asymmetric Synthesis of 2-Aryl(alkyl)-2,3-dihydro-4-pyridones [PDF]
trans-3-Amino-b-lactams were evaluated as the chiral building blocks in the aza-Diels – Alder reaction of azetidin-2-one-tethered imines with siloxydienes under Lewis acid catalysis, as a route for the asymmetric synthesis of 2-aryl(alkyl)-2,3-dihydro ...
Habuš, Ivan+3 more
core +1 more source
Unprotected glycosyl pyridinium salts may be accessed in a single step from the corresponding unprotected sugar in aqueous solution. Whilst meta‐ and para‐substitution is well tolerated, ortho substitution of the N‐heterocycle inhibits product formation. Electrochemical studies revealed reduction potentials in the range of −0.9 to −1.4 V.
Daniel Chong+2 more
wiley +1 more source
Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones
Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle+3 more
doaj +1 more source
The Rh(III)-catalyzed synthesis of 4-substituted isoquinolones and 2-pyridones by the annulation of N-methoxyamides and nitroalkenes has been developed. Both aliphatic and aromatic nitroalkenes were effective inputs.
T. Potter+3 more
semanticscholar +1 more source
Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
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