Results 81 to 90 of about 12,719 (269)

One‐Step Aqueous Synthesis of Glycosyl Pyridinium Salts, Electrochemical Study, and Assessment of Utility as Precursors of Glycosyl Radicals Using Photoredox Catalysis

ChemistryOpen, EarlyView.
Unprotected glycosyl pyridinium salts may be accessed in a single step from the corresponding unprotected sugar in aqueous solution. Whilst meta‐ and para‐substitution is well tolerated, ortho substitution of the N‐heterocycle inhibits product formation. Electrochemical studies revealed reduction potentials in the range of −0.9 to −1.4 V.
Daniel Chong, Paula A. Brooksby, Antony J. Fairbanks   +2 more
wiley   +1 more source

Harnessing Molecular and Bioactivity Network Analysis to Prioritize Antibacterial Compound Isolation From Ant‐Associated Fungi

Phytochemical Analysis, EarlyView.
ABSTRACT Introduction Antimicrobial resistance is a global public health problem that requires the development of new bioactive compounds. In this context, metabolomic analyses can expedite the research of fungal metabolites as a valuable resource. Objectives To investigate the metabolic profiles and isolate antibacterial compounds from micromycetes ...
Ángel S. Aguilar‐Colorado, Jesús Morales‐Jiménez, José Rivera‐Chávez   +2 more
wiley   +1 more source

Synthesis and chemical properties of 3-acyl- and 3-carbethoxy-4-pyrones [PDF]

, 2013
Реакция 1-арил-2-диметиламинометиленбутан-1,3-дионов с диэтиоксалатом в присутствии гидрида натрия в ТГФ приводит к образованию этил 5-ароил-4-оксо-4Н-пиран-2- карбоксилатам, из которых 4-оксо-6-арил-4Н-пиран-2-карбоновые кислота (6- арилкомановая ...
Obydennov, D. L., Обыденнов, Д. Л.   +1 more
core  

Versatile and Enantioselective Preparation of Planar-Chiral Metallocene-Fused 4-Dialkylaminopyridines and Their Application in Asymmetric Organocatalysis [PDF]

, 2020
A series of ferrocene-fused planar-chiral N-tosyl-4-pyridones (S)-2b-d were prepared in enantiomerically pure forms. Starting with the chiral ferrocenyl acetals, 1-[(2S,4S)-4-methoxymethyl-1,3-dioxan-2-yl]-1',2',3',4',5'-R5-ferrocenes ((–)-3b, R = Me; (–)
Kimura, Ryosuke, Konishi, Takuma, Liu, Qiang, Ogasawara, Masamichi, Wada, Shiro, Yasue, Risa, Yoshida, Kazuhiro   +6 more
core  

Infrared Assisted Production of 3,4-Dihydro-2(1H)-pyridones in Solvent-Free Conditions [PDF]

, 2011
A green approach for the synthesis of a set of ten 4-aryl substituted-5-alcoxy carbonyl-6-methyl-3,4-dihydro-2(1H)-pyridones using Meldrum’s acid has been devised, the absence of solvent and the activation with infrared irradiation in addition to a ...
Alberola, Anastas, Bayley, Brickner, Bristol, Brun, Cox, Curran, Francisco J. Pérez, Gabriel A. Arroyo, Gómez-Pliego, Hortensia Rodríguez, Iven, Joel O. Martínez, Jones, Jones, Kelly, Kozikowski, Lemke, M. Olivia Noguez, Margarita Suárez, Martínez, McKillop, Miranda, Mohrle, Molero, Morales, Murray, Noguez, Ochoa, Osnieski Martín, Paulvannan, Pihlaja, René Miranda, Schultz, Smith, Suárez, Suárez, Tundo, Vanessa Marcelino, Velasco, Velasco-Bejarano, Wender, Williams, Zhu   +44 more
core   +3 more sources

Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial

Aging Cell, EarlyView.
Nicotinamide riboside improved arterial stiffness (cardio–ankle vascular index), reduced skin ulcer area, and showed a trend toward mitigating heel pad thinning in patients with Werner syndrome, with no serious adverse events. Metabolomic analysis revealed a significant decrease in creatinine, suggesting a potential suppression of renal functional ...
Mayumi Shoji, Hisaya Kato, Masaya Koshizaka, Hiyori Kaneko, Yusuke Baba, Takahiro Ishikawa, Naoya Teramoto, Daisuke Kinoshita, Ayano Yamaguchi, Yukari Maeda, Yosuke Inaba, Yuki Shiko, Yoshihito Ozawa, Vilhelm A. Bohr, Yoshiro Maezawa, Koutaro Yokote   +15 more
wiley   +1 more source

A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones

Molecules, 2019
Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied.
Federica Arioli, Maria Pérez, Celeste Are, Elies Molins, Joan Bosch, Mercedes Amat   +5 more
doaj   +1 more source

New approach to condensed pyrid-2-ones [PDF]

, 2002
We wish to report a simple procedure for the preparation of 5-substituted-thienopyridin-7-ones and 7-substituted-1,6-naphthyridin-5(6H)-ones, in good yields, from the dianions of 3-methylthiophene-2-carboxylic and 2-methylnicotinic acids on treatment ...
Brun Sanchez, Eva Maria, Gil Grau, Salvador, Parra Alvarez, Margarita   +2 more
core  

Waltherione C and cleomiscosin from Melochia umbellata var. Degrabrata K. (Malvaceae), biosynthetic and chemotaxonomic significance [PDF]

, 2014
Waltherione C, a 4-quinolinone secondary metabolite, and cleomiscosin have been isolated from Melochia umbellata (Malvaceae).A biosynthetic scheme incorporating the unique 4-pyridones and 4-quinolones isolated from Melochia and Waltheria spp.
Noor, Alfian, Soekamto, Nunuk H.
core   +1 more source

Chemical constitutions in the Colour Index™: A century of colourant classification

Coloration Technology, EarlyView.
Abstract This article details how the Colour Index™ (CI) system categorises and unambiguously labels commercial dyes and pigments based upon their chemical constitutions. It outlines the current process by which colourants that are new to the market find a place within CI and acquire generic identifiers.
Andrew Towns
wiley   +1 more source