Results 111 to 120 of about 197,991 (343)

RESEARCHES ON PYRIMIDINES: SYNTHESIS OF URACIL-4-ACETIC ACID. [PDF]

, 1908
Henry L. Wheeler, Leonard M. Liddle
openalex   +1 more source

UV-induced damage to DNA: effect of cytosine methylation on pyrimidine dimerization

Signal Transduction and Targeted Therapy, 2017
Methylation/demethylation of cytosine plays an important role in epigenetic signaling, the reversibility of epigenetic modifications offering important opportunities for targeted therapies.
Lara Martínez-Fernández, A. Banyasz, L. Esposito, D. Markovitsi, R. Improta   +4 more
semanticscholar   +1 more source

The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α‐ACER2‐Ceramide Signaling Axis

Advanced Science
Metabolic abnormalities contribute to the pathogenesis of obesity and its complications. Yet, the understanding of the interactions between critical metabolic pathways that underlie obesity remains to be improved, in part owing to the lack of ...
Huiying Liu, Pengcheng Wang, Feng Xu, Qixing Nie, Sen Yan, Zhipeng Zhang, Yi Zhang, Changtao Jiang, Xiaomei Qin, Yanli Pang   +9 more
doaj   +1 more source

Thioxopyrimidine in Heterocyclic Synthesis I: Synthesis of Some Novel 6-(Heteroatom-substituted)-(thio)pyrimidine Derivatives

Journal of Chemistry, 2013
A series of novel N-cycloalkanes, morpholine, piperazines, pyrazole, pyrimidine, benzimidazolo[1,2-a]pyrimidine, 1,2,3,4-tetrazolo[1,5-a]pyrimidine, azopyrazolo[1,5- a]pyrimidine, pyrimido[4', 5':3,4]pyrazolo[1,5-a]pyrimidines and pyridine derivatives ...
Yuh-Wen Ho, Maw Cherng Suen
doaj   +1 more source

INCORPORATION OF FORMATE-C ¹⁴ INTO THE PYRIMIDINE MOIETY OF THIAMINE, [PDF]

, 1959
Martin J. Pine, Robert Guthrie
openalex   +1 more source

Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion

OncoTarget, 2017
Gemcitabine, an anti-cancer chemotherapy drug, has additionally shown the antiviral activity against a broad range of viruses and we also have previously reported its synergistic antiviral activity with ribavirin against enteroviruses.
Kyungjin Lee, Dong‐eun Kim, Kyoung-Soon Jang, Seong‐Jun Kim, Sungchan Cho, Chonsaeng Kim   +5 more
semanticscholar   +1 more source

A Broadly Applicable Strategy to Aminate Azines Enabled by Electronically Tuned Phosphine Reagents

Angewandte Chemie International Edition, EarlyView.
We have developed a pyridine C4‐amination reaction via phosphonium salt intermediates, where an electronically tuned phosphine is key to successful C─N bond formation. The process accommodates aliphatic amines, (heteroaryl)anilines, hydrazines, and nitrogen heteroaromatics, as well as a variety of pyridine building blocks and late‐stage C─N couplings ...
Ren‐Rong Liu, Jeffrey N. Levy, Andrew McNally   +2 more
wiley   +1 more source

RESEARCHES ON PYRIMIDINES: SYNTHESIS OF CYTOSINE-5-ACETIC ACID. [FIFTY-FIRST PAPER.]¹ [PDF]

, 1911
Treat B. Johnson, Harley T. Peck, Joseph A. Ambler   +2 more
openalex   +1 more source

The Origin of the Feedstock Molecules for Life on the Hadean Earth

Angewandte Chemie International Edition, EarlyView.
The origin of life in the Hadean eon required the formation of amino acids and nucleosides among the key molecules of life. In an often postulated strongly reducing atmosphere, HCN and its derivatives are robustly formed as plausible starting molecules. But HCN does not form in a Hadean, weakly reducing atmosphere.
Nikolai Diukarev, Erik Boinowitz, Jonas Feldmann, Stefan Wiedemann, Aleksandr Mikheev, Sidney Becker, Thomas Carell   +6 more
wiley   +1 more source

Flowering in Fruit Trees and Annual Plants as Affected by Purines, Pyrimidines and Triiodobenzoic Acid. [PDF]

, 1959
B. Kessler, RPM Bak, A. Cohen
openalex   +1 more source