Results 91 to 100 of about 35,554 (229)

π‐Expanded Nitrogen‐Cation (N+)‐Doped Polycyclic Aromatic Hydrocarbons: A Review of Intramolecular Cyclization Routes to Benzo[c]Quinolizinium, Triazinium, Pyridoquinazolinium, and Pyridoquinoxalinium Frameworks

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This review surveys recent progress in the synthesis of extended aromatic quinolizinium derivatives via intramolecular SNAr and oxidative 6π‐electrocyclization. Conventional thermal approaches are discussed alongside emerging, sustainable activation methods such as electrosynthesis and photochemical processes.
Marine Labro   +2 more
wiley   +1 more source

Development of Novel Pyrimidine Nucleosides as Potential Anticancer Agents: Synthesis, Characterization, and Invitro Evaluation against pancreatic cancer [PDF]

open access: green, 2023
Esther Frimpong   +8 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Substrate identification of putative NCS1 and NCS2 nucleobase transporters in Pseudomonas aeruginosa

open access: yesmBio
Pseudomonas aeruginosa is an opportunistic pathogen that can salvage nucleobases from the environment to conserve nutrients that would otherwise be spent on de novo nucleotide biosynthesis.
Corey Kennelly, Arthur Prindle
doaj   +1 more source

The Protective Effects of Membrane‐Separated Ripe Pu‐Erh Tea Extracts Against Chronic Alcoholic Liver Injury

open access: yesFood Frontiers, EarlyView.
In this study, we investigated the protective effects of different membrane‐separated ripe Pu‐erh tea on alcohol‐induced liver injury. The result indicated that ripe Pu‐erh tea separated by a 50 nm ceramic membrane (molecular weight < 300 kDa) has the best effect on preventing ALD.
Sibo Zhao   +9 more
wiley   +1 more source

Protective Effects of Auricularia auricula Polysaccharides on Acute Lung Injury by Regulating Intestinal Flora and Metabolism

open access: yesFood Frontiers, EarlyView.
Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu   +8 more
wiley   +1 more source

Fish Oil Ameliorates Glycolipid Metabolism Disorders Induced by Long‐Term Potato Chip Diet Through Gut‐Liver Axis

open access: yesFood Frontiers, EarlyView.
Fried potato consumption is increasingly associated with metabolic disorders, yet preventive strategies remain poorly understood. In a 13‐week mouse model, long‐term potato chip intake induced significant glycolipid metabolic disturbances and tissue damage, which were ameliorated by fish oil supplementation through modulation of inflammation, hepatic ...
Xuzhi Wan   +10 more
wiley   +1 more source

Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells

open access: diamond, 2017
Satoshi Imanishi   +6 more
openalex   +2 more sources

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