Results 151 to 160 of about 83,545 (299)

Pyrin ve pyrin ile ilişkili proteinler; PSTPIP1 ve siva`nın inflamasyondaki rolü

, 2020
99
openaire   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

AMPK Phosphorylation Modulates Pain by Activation of NLRP3 Inflammasome [PDF]

, 2016
Impairment in adenosine monophosphate-activated protein kinase (AMPK) activity and NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome activation are associated with several metabolic and inflammatory diseases.
Alcocer-Gómez, Elísabet, Bullon, Pedro, Carrión, Ángel Manuel, Garrido Maraver, Juan, Marín-Aguilar, Fabiola, Román Malo, Lourdes Victoria   +5 more
core  

Scalp Microbiome Alterations in Androgenetic Alopecia: Patterns and Emerging Mechanistic Insights

International Journal of Dermatology, EarlyView.
Summary of the microbiome‐lipid‐microinflammation axis in androgenetic alopecia (AGA). Altered sebaceous gland activity, shifts in microbial abundance on the scalp and hair follicle, and follicular microinflammation interact bidirectionally, each reinforcing the others.
Aditya K. Gupta, Elizabeth M. Teasell, Amanda Liddy, Vasiliki Economopoulos   +3 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

A plasmonic biosensor pre-diagnostic tool for Familial Mediterranean Fever

Nature Communications
Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disorder, primarily observed in populations around the Mediterranean Sea, linked to MEFV gene mutations.
Idil Karaca Acari, Fatma Kurul, Meryem Beyza Avci, S. Deniz Yasar, Seda Nur Topkaya, Ceyhun Açarı, Erbil Ünsal, Balahan Makay, Süleyman Köytepe, Burhan Ateş, İsmet Yilmaz, Turgay Seçkin, Arif E. Cetin   +12 more
doaj   +1 more source

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez, Margarida B. Almeida, Joana F. Sacramento, Elena Olea, Jesus Prieto‐Lloret, Asuncion Rocher, Silvia V. Conde   +6 more
wiley   +1 more source

Design principles for inflammasome inhibition by pyrin-only-proteins

eLife
Inflammasomes are filamentous signaling platforms essential for host defense against various intracellular calamities such as pathogen invasion and genotoxic stresses.
Shuai Wu, Archit Garg, Zachary Mazanek, Gretchen Belotte, Jeffery J Zhou, Christina M Stallings, Jacob Lueck, Aubrey Roland, Michael A Chattergoon, Jungsan Sohn   +9 more
doaj   +1 more source

PW01-001 – Pyrin-PSTPIP1 relation during cell migration [PDF]

, 2013
ZY Akkaya, Banu Balcı‐Peynircioğlu, Arda Çetinkaya, Nuhan Puralı, Engin Yılmaz   +4 more
openalex   +1 more source

PYRIN fever [PDF]

Nature Reviews Molecular Cell Biology, 2002
openaire   +1 more source