Results 71 to 80 of about 35,163 (154)

PYRIN fever [PDF]

Nature Reviews Molecular Cell Biology, 2002
openaire   +1 more source

Design principles for inflammasome inhibition by pyrin-only-proteins

eLife
Inflammasomes are filamentous signaling platforms essential for host defense against various intracellular calamities such as pathogen invasion and genotoxic stresses.
Shuai Wu, Archit Garg, Zachary Mazanek, Gretchen Belotte, Jeffery J Zhou, Christina M Stallings, Jacob Lueck, Aubrey Roland, Michael A Chattergoon, Jungsan Sohn   +9 more
doaj   +1 more source

PSTPIP1 and pyrin, two key regulators of macrophage differentiation

European Journal of Cell Biology
Background: Monocytes develop from hematopoietic stem cells; migrate into the tissue, where they undergo a stimulation-dependent and tissue specific differentiation into macrophages imprinting specific inflammatory functions.
Philipp Berger, Lisa Wilming, Ricarda Jürgens, Yevheniia Minchuk, Sophia Leußink, Shrey Gandhi, Carolin Walter, Sophie-Marie Wind, Dominik Heider, Lukas Lamparter, Milos Galic, Monika Stoll, Selina K. Jorch, Johannes Roth, Judith Austermann, Olesja Fehler   +15 more
doaj   +1 more source

Pyrin‐associated autoinflammation with neutrophilic dermatosis: A case report

The Journal of Dermatology
AbstractPyrin‐associated autoinflammation with neutrophilic dermatosis (PAAND) is a rare, monogenic, autoinflammatory disorder caused by mutations in exon 2 of the MEFV gene. Characterized by neutrophilic dermatosis, recurrent fever, and arthralgia, this syndrome presents a diagnostic challenge due to its low prevalence and varied clinical ...
Rocío C. Bueno‐Molina, Juan‐Carlos Hernández‐Rodríguez, Teresa Zulueta‐Dorado, Jose‐Juan Pereyra‐Rodriguez   +3 more
openaire   +2 more sources

Pyrin inflammasome and familial Mediterranean fever : deciphering the role of B30.2 and CHS in pyrin regulation

L'inflammasome pyrine et la fièvre Méditerranéenne familiale : le rôle du B30.2 et du CHS dans la régulation de pyrine L'inflammasome pyrine est activé en réponse à l'inhibition de RhoA par des pathogènes. La régulation de pyrine se déroule en deux étapes : la phosphorylation de pyrine par les kinases PKN1/2, eux-mêmes des effecteurs de
openaire   +1 more source

Modulation of Inflammasome Activity by miR-197-3p in Familial Mediterranean Fever Mouse Macrophages. [PDF]

Arch Rheumatol
Akkaya-Ulum YZ, Sen B, Akbaba TH, Balci-Peynircioglu B.   +3 more
europepmc   +1 more source

The Role of Inflammasome in the Pathogenesis of Alopecia Areata: NLRP3 and Its Cascade Contribute to the Onset and Early Stage of Alopecia Areata. [PDF]

Ann Dermatol
Lim JH, Kang DH, Moon H, Kwon SH, Lew BL.   +4 more
europepmc   +1 more source

Pyrin ve pyrin ile ilişkili proteinler; PSTPIP1 ve siva`nın inflamasyondaki rolü

, 2020
99
openaire   +1 more source

Transcriptomic Modulation of Inflammasome-Related Genes Following Metformin Administration in Breast Cancer Patients with Paclitaxel-Induced Neuropathy. [PDF]

Clin Pharmacol
Malayeri A, Etemad Nezhad M, Ramesh F, Karimpourian H, Mahmoudian-Sani MR.   +4 more
europepmc   +1 more source

Catalpol ameliorates diabetic retinal vascular endothelial injury by suppressing NLRP3 inflammasome <i>via</i> targeting METTL3-m⁶A modification. [PDF]

Int J Ophthalmol
Liu JY, Zhu JY, Xiao YF, Ge YR, Yan F, Jiang Q.   +5 more
europepmc   +1 more source