Results 121 to 130 of about 70,546 (390)

Mannich Reaction of Secondary Benzylzinc Reagents: Synthesis of α,β‐Disubstituted β‐Arylethylamines

Asian Journal of Organic Chemistry, EarlyView.
The organometallic Mannich multicomponent reaction (MCR) of secondary benzylzinc reagents is described. The final α,β‐disubstituted β‐arylethylamines are obtained in generally high yields. The reaction is however characterized by a general lack of diastereoselectivity. A possible explanation is provided.
Baptiste Leroux, Federico Banchini, Olivier Jackowski, Alejandro Perez‐Luna, Fabrice Chemla, Marc Presset, Erwan Le Gall   +6 more
wiley   +1 more source

Crystal structure of 6-(4-chlorophenyl)-6a-nitro-6a,6b,8,9,10,12a-hexahydro-6H,7H-spiro[chromeno[3,4-a]indolizine-12,11′-indeno[1,2-b]quinoxaline]

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound, C35H27ClN4O3, crystallized with two independent molecules (A and B) in the asymmetric unit. In both molecules, the pyran and pyridine rings adopt envelope and chair conformations, respectively.
S. Syed Abuthahir, M. NizamMohideen, V. Viswanathan, D. Velmurugan, J. Nagasivarao   +4 more
doaj   +1 more source

One-Pot Synthesis, X-ray Single Crystal and Molecular Insight of Enaminone-Based β-Morpholino-/N-Methylpiperazinyl-/Pyrrolidinylpropiophenone

Crystals, 2020
One-pot synthesis of three enaminones, (E)-1-(4-chlorophenyl)-3-morpholinoprop-2-en-1-one 1, (E)-1-(4-chlorophenyl)-3-(4-methylpiperazin-1-yl)prop-2-en-1-one 2, and (E)-1-(4-chlorophenyl)-3-(pyrrolidin-1-yl)prop-2-en-1-one 3 were achieved.
Assem Barakat, Saied M. Soliman, Matti Haukka, Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, M. Ali, Mohammed Rafi Shaik   +6 more
doaj   +1 more source

Interaction of GABA and Excitatory Amino Acids in the Basolateral Amygdala: Role in Cardiovascular Regulation [PDF]

, 1997
Activation of the amygdala in rats produces cardiovascular changes that include increases in heart rate and arterial pressure as well as behavioral changes characteristic of emotional arousal.
Cook, Jennifer C., Gregg, Adam E., Sanders, Brian J., Soltis, Robert P.   +3 more
core   +2 more sources

Zur Kenntniss des Pyrrolidins [PDF]

Berichte der deutschen chemischen Gesellschaft, 1899
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openaire   +2 more sources

Synthesis of (‐)‐8a epi‐Lentiginosine via Tsuji‐Trost Reaction of d‐Glucose‐Derived Allylic Alcohols and Crystal Structure Analysis

Asian Journal of Organic Chemistry, Accepted Article.
An indolizidine alkaloid, (‐)‐8a‐epi‐lentiginosine was synthesized from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji‐Trost reaction of non‐derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring to give the desired product in good yield and high diasterespecificity stereospecificity (dr = 97:3).
Sunisa Akkarasamiyo, Patchreenart Saparpakorn, Andreas Orthaber, Joseph Samec   +3 more
wiley   +1 more source

Crystal structure of methyl 7-phenyl-6a,7,7a,8,9,10-hexahydro-6H,11aH-thiochromeno[3,4-b]pyrrolizine-6a-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C22H23NO2S, the inner pyrrolidine ring (A) adopts an envelope conformation with the methine C atom opposite the fused C—N bond as the flap.
M. P. Savithri, M. Suresh, R. Raghunathan, R. Raja, A. SubbiahPandi   +4 more
doaj   +1 more source

Discovery of a Potent α ‑ Galactosidase Inhibitor by in Situ Analysis of a Library of Pyrrolizidine − (Thio)urea Hybrid Molecules Generated via Click Chemistry [PDF]

, 2018
The parallel synthesis of a 26-membered-library of aromatic/aliphatic-(thio)urea-linked pyrrolizidines followed by in situ biological evaluation toward α -galactosidases has been carried out.
Carmona Asenjo, Ana Teresa, Elías Rodríguez, María del Pilar, Ide, Daisuke, Kato, Atsushi, Miyawaki, Shota, Moreno Vargas, Antonio José, Pingitore, Valeria, Robina Ramírez, Inmaculada, Álvarez González, Eleuterio   +8 more
core   +1 more source

Crystal structure of methyl 3′-benzamido-4′-(4-methoxyphenyl)-1′-methylspiro[indeno[1,2-b]quinoxaline-11,2′-pyrrolidine]-3′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title compound, C35H30N4O3, the spiro C atom connects the five-membered pyrrolidine ring and the indenoquinoxaline ring system. The pyrrolidine ring adopts a twist conformation. An intramolecular N—H...N interaction between the amino group and the
Kuppan Chandralekha, Adukamparai Rajukrishnan Sureshbabu, Deivasigamani Gavaskar, Srinivasakannan Lakshmi   +3 more
doaj   +1 more source

Design and Synthesis of Oxazoline-Based Scaffolds for Hybrid Lewis Acid/Lewis Base Catalysis of Carbon–Carbon Bond Formation [PDF]

, 2016
A new class of hybrid Lewis acid/Lewis base catalysts has been designed and prepared with an initial objective of promoting stereoselective direct aldol reactions.
Benoit, Adam R., Dockendorff, Chris, Porter, Jacob D., Shanaa, Alaa, Virdi, Rajdeep S., Wiedenhoeft, Dennis, Wu, Yibiao   +6 more
core   +1 more source