Results 81 to 90 of about 17,768 (339)
A regio- and stereoselective ω-transaminase/monoamine oxidase cascade for the synthesis of chiral 2,5-disubstituted pyrrolidines [PDF]
, 2014 Biocatalytic approaches to the synthesis of optically pure chiral amines, starting from simple achiral building blocks, are highly desirable because such motifs are present in a wide variety of important natural products and pharmaceutical compounds ...
Aggarwal +38 more
core +1 more source
Advanced Synthesis &Catalysis, Accepted Article.A straightforward synthesis of spirolactones from carbonyls via N‐tosylhydrazones is described. The process consist in the reaction between the N‐tosylhydrazone and ethoxycarbonylethylboronic acid or ethoxycarbonylpropylboronic acid, leading to spiro γ‐butyrolactones or δ‐valerolactones respectively. The transformation takes place by carboborylation of
Lucía López +3 more
wiley +1 more source
Supramolecular Gels as Active Tools for Reaction Engineering
Angewandte Chemie, EarlyView.The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley +2 more sources
Recent Developments in Radical Mediated Synthesis of Organostannanes.
Advanced Synthesis &Catalysis, EarlyView.Abstract The present review aims to provide an overview of the recent developments in the preparation of aryl‐ or alkenyl stannanes via carbon‐ and tin‐centered radicals enabling chemists to synthesize organostannyl derivatives with high efficiency and under mild conditions.
Qianhang Ren +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.Concise total syntheses of five leuconoxine alkaloids have been achieved using a pyrrole‐centered strategy, which features a newly developed palladium/norbornene‐catalyzed pyrrole double C─H functionalization method, a divergent late‐stage oxidative dearomatization tactic, and no use of protecting groups.
Xin Liu +5 more
wiley +2 more sources
Carbohydrate-auxiliary assisted preparation of enantiopure 1,2-oxazine derivatives and aminopolyols
Beilstein Journal of Organic Chemistry, 2012 An approach to enantiopure hydroxylated 2H-1,2-oxazine derivatives is presented utilizing the [3 + 3] cyclisation of lithiated alkoxyallenes and an L-erythrose-derived N-glycosyl nitrone as precursors.
Marcin Jasiński +2 more
doaj +1 more source
Synthesis of Spiro Pyrrolidines From the Addition of Schiff Bases to -Arylidene Cyclohexanones [PDF]
مجلة التربية والعلم, 2008 A series of -arylidene cyclohexanones (1-4) had been prepared via Claisen-Schmidt condensation, while other series of N-arylidene benzylamines (Schiff bases 5-10) had also been synthesized by equimolar addition.
A Al-Hamdany, A Mustafa, ِA Hamza
doaj +1 more source
Diastereodivergent synthesis of chiral tetrahydropyrrolodiazepinediones via a one-pot intramolecular aza-Michael/lactamization sequence [PDF]
, 2018 A modular and diastereodivergent synthesis of tetrahydro-1H-pyrrolo[1,2d]diazepine-(2,5)-diones is presented. The tetrahydropyrrolodiazepinedione scaffold is obtained via a base-mediated three-step isomerization/tandem cyclization of amino acid-coupled ...
Brown, Lauren E. +3 more
core +1 more source
Removal of the Pyrrolidine Group by Dehydrogenation of a 4‐Pyrrolidin‐2‐yl‐tetrahydroisoquinoline [PDF]
Archiv der Pharmazie, 1992 AbstractDehydrogenation of 6,7‐dimethoxy‐1‐methyl‐4‐(N‐methyl‐pyrrolidin‐2‐yl)‐3,4‐dihydroisoquinoline (9) by Pd/C in tetraline leads to dehydrogenated products, rearrangement, and elimination of the pyrrolidine group mainly as N‐methylpyrrolidine (Scheme 3).
Engelbert Seidl +2 more
openaire +2 more sources
Advanced Science, EarlyView.The biosynthetic mechanism of novel natural tetramic acid S‐TeA in Alternaria alternata is elucidated. Threonine acts as a precursor for 2‐amino‐3‐methylhexanoic acid (AMHA) synthesis via eight key enzymes from the branched‐chain amino acid biosynthetic pathway in the mitochondrion, wherein three unique enzymes (IPMS, IPMDH, and ISMD) play critical ...
He Wang +9 more
wiley +1 more source