Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. [PDF]
PLoS ONE, 2015 Liver fibrosis represents the consequences of a sustained wound healing response to chronic liver injuries, and its progression toward cirrhosis is the major cause of liver-related morbidity and mortality worldwide.
Dongwei Jia +5 more
doaj +4 more sources
Deep Learning‐Driven Exploration of Pyrroloquinoline Quinone Neuroprotective Activity in Alzheimer's Disease [PDF]
Advanced ScienceAlzheimer's disease (AD) is a pressing concern in neurodegenerative research. To address the challenges in AD drug development, especially those targeting Aβ, this study uses deep learning and a pharmacological approach to elucidate the potential of ...
Xinuo Li +10 more
doaj +2 more sources
Effect of pyrroloquinoline quinone on skin aging in Bmi-1 KO mice and underlying mechanisms. [PDF]
PLoS ONETo investigate the effect of pyrroloquinoline quinone (PQQ) on skin aging in the Bmi-1 KO mice and its underlying mechanisms, we administered a normal diet to both Wild type mice (WT) and Bmi-1 KO mice, while supplementing the diet of Bmi-1 KO mice with ...
Bin Li +3 more
doaj +2 more sources
Development of an Engineered Bacterial Endophyte: Promoting Plant Growth Through Pyrroloquinoline Quinone (PQQ) Synthesis [PDF]
MicroorganismsEndophytic bacteria are a group of microorganisms that can intercellularly colonize plant hosts without causing apparent damage or disease. Our previous works found that a pyrroloquinoline quinone (PQQ)-producing endophyte could promote plant growth and ...
Ti Fang +7 more
doaj +2 more sources
Metabolic and Biochemical Effects of Pyrroloquinoline Quinone (PQQ) on Inflammation and Mitochondrial Dysfunction: Potential Health Benefits in Obesity and Future Perspectives [PDF]
AntioxidantsObesity is defined as a complex, systemic disease characterized by excessive and dysfunctional adipose tissue, leading to adverse health effects. This condition is marked by low-grade inflammation, oxidative stress, and metabolic abnormalities, including
Davide Charrier +7 more
doaj +2 more sources
The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations. [PDF]
Angew Chem Int Ed EnglNatural alcohol and sugar dehydrogenases that utilize the redox cofactor pyrroloquinoline quinone (PQQ) can be repurposed for enantioselective photoredox catalysis. Upon blue‐light irradiation, redox‐neutral radical cyclizations are catalyzed. This work adds a new class of enzymes to the toolbox of photobiocatalysis.
Bahukhandi SB +8 more
europepmc +3 more sources
The impact of six-week dihydrogen-pyrroloquinoline quinone supplementation on mitochondrial biomarkers, brain metabolism, and cognition in elderly individuals with mild cognitive impairment: a randomized controlled trial [PDF]
The Journal of Nutrition, Health and AgingObjectives: To assess the impact of medium-term supplementation with dihydrogen and pyrroloquinoline quinone (PQQ) on mitochondrial biomarkers, brain metabolism, and cognition in elderly individuals diagnosed with mild cognitive impairment.
Sonja Baltic +10 more
doaj +2 more sources
Production and Radioprotective Effects of Pyrroloquinoline Quinone [PDF]
International Journal of Molecular Sciences, 2011 Pyrroloquinoline quinone (PQQ) was produced by fermentation of the Methylovorus sp. MP688 strain and purified by ion-exchange chromatography, crystallization and recrystallization.
Du, Bao-Hua +12 more
core +7 more sources
Antiviral Effects of Pyrroloquinoline Quinone through Redox Catalysis To Prevent Coronavirus Infection [PDF]
ACS Omega, 2023 Nur Syafiqah Mohamad Ishak +2 more
doaj +2 more sources
Protective Effect of Pyrroloquinoline Quinone (PQQ) against Renal Ischemia-Reperfusion Injury in Rat [PDF]
Iranian Journal of Veterinary Surgery, 2023 Ischemia/reperfusion can cause tissue damage and affect organ function. Ischemia-reperfusion injury (IRI) occurs in a variety of clinical manifestations such as stroke, trauma, and surgery.
Elnaz Taheran +2 more
doaj +1 more source