Results 61 to 70 of about 7,956 (190)

Characterization of a λ-Carrageenase Mutant with the Generation of Long-Chain λ-Neocarrageenan Oligosaccharides

open access: yesFoods
λ-carrageenan oligosaccharides can be widely applied in the food, pharmaceutical, medicine and cosmetic industries due to their abundant bioactivities, and they are important products for the high-value utilization of λ-carrageenan.
Zewei Lu   +6 more
doaj   +1 more source

Effects of Electric Potential Treatment of a Chromium Hexacyanoferrate Modified Biosensor Based on PQQ-Dependent Glucose Dehydrogenase

open access: yesSensors, 2010
A novel potential treatment technique applied to a glucose biosensor that is based on pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase (GDH) and chromium hexacyanoferrate (CrHCF) incorporated into a platinum (Pt) electrode was demonstrated.
Ta-Feng Tseng   +3 more
doaj   +1 more source

Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. [PDF]

open access: yesPLoS ONE, 2011
We have reported that pyrroloquinoline quinone (PQQ) improves reproduction, neonatal development, and mitochondrial function in animals by mechanisms that involve mitochondrial related cell signaling pathways.
Kathryn Bauerly   +8 more
doaj   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

open access: yesAdvanced Science, Volume 12, Issue 41, November 6, 2025.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Pyrolyzed Walnut Shell‐Based Flexible Electrodes for Magnetically Triggered ON/OFF DNA Release

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
A magnetically actuated DNA release system using walnut shell‐derived electrodes enables ON/OFF switching of electron transfer by controlling DNA hybridization with magnetic beads. A magnetically gated, enzymatically driven DNA release platform based on sustainable pyrolyzed walnut shell‐derived carbon electrodes is reported.
Paolo Bollella   +5 more
wiley   +1 more source

CRISPRe: An innate transcriptional enhancer for endogenous genes in CRISPR-Cas immunity

open access: yesiScience, 2023
Summary: CRISPR-Cas system has been repurposed to the promising strategy of CRISPR-based transcriptional interference/activation (CRISPRi/CRISPRa) without eliciting DNA breaks that enables Cas complex a block for transcription initiation or elongation ...
Dan Li   +5 more
doaj   +1 more source

Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives [PDF]

open access: yes, 2017
Nitrogen-based tetracyclic ortho-quinones (naphtho[1'2':4.5]imidazo[1,2-a]pyridine-5,6-diones, NPDOs) and their nitro-substituted derivatives (nitro-(P)NPDOs) were obtained by condensation of substituted 2,3-dichloro- 1,4-naphthoquinones with 2-amino ...
Anusevičius, Žilvinas   +7 more
core   +1 more source

Portable multimodal sensing system for screening of diabetes mellitus from human urine

open access: yesVIEW, Volume 6, Issue 5, October 2025.
A compact multimodal sensing device was developed for the simultaneous detection of glucose and acetone from urine samples. Combining electrochemical and gas sensors, the device demonstrates reliable performance within clinically relevant ranges. This portable system offers a holistic metabolic assessment, supporting early screening of diabetes and ...
Mario Soto Martinez   +5 more
wiley   +1 more source

The role of DJ-1 in enhancing mitochondrial quality control [PDF]

open access: yes, 2013
Thesis (M.A.)--Boston UniversityDJ-1 is a cytosolic sensor for oxidative damage which acts on the Mitochondria. It works to curb the negative effects of high membrane potential in mitochondria, but the mechanism of action is still uncertain.
Lingiah, Krishna Anand
core   +1 more source

Parkinson's disease: autoimmunity and neuroinflammation [PDF]

open access: yes, 2016
Parkinson's disease is a neurodegenerative disease that causes the death of dopaminergic neurons in the substantia nigra. The resulting dopamine deficiency in the basal ganglia leads to a movement disorder that is characterized by classical parkinsonian ...
CINIGLIO APPIANI, MARIO   +9 more
core   +1 more source

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