Results 61 to 70 of about 7,956 (190)
λ-carrageenan oligosaccharides can be widely applied in the food, pharmaceutical, medicine and cosmetic industries due to their abundant bioactivities, and they are important products for the high-value utilization of λ-carrageenan.
Zewei Lu +6 more
doaj +1 more source
A novel potential treatment technique applied to a glucose biosensor that is based on pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase (GDH) and chromium hexacyanoferrate (CrHCF) incorporated into a platinum (Pt) electrode was demonstrated.
Ta-Feng Tseng +3 more
doaj +1 more source
Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats. [PDF]
We have reported that pyrroloquinoline quinone (PQQ) improves reproduction, neonatal development, and mitochondrial function in animals by mechanisms that involve mitochondrial related cell signaling pathways.
Kathryn Bauerly +8 more
doaj +1 more source
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley +1 more source
Pyrolyzed Walnut Shell‐Based Flexible Electrodes for Magnetically Triggered ON/OFF DNA Release
A magnetically actuated DNA release system using walnut shell‐derived electrodes enables ON/OFF switching of electron transfer by controlling DNA hybridization with magnetic beads. A magnetically gated, enzymatically driven DNA release platform based on sustainable pyrolyzed walnut shell‐derived carbon electrodes is reported.
Paolo Bollella +5 more
wiley +1 more source
CRISPRe: An innate transcriptional enhancer for endogenous genes in CRISPR-Cas immunity
Summary: CRISPR-Cas system has been repurposed to the promising strategy of CRISPR-based transcriptional interference/activation (CRISPRi/CRISPRa) without eliciting DNA breaks that enables Cas complex a block for transcription initiation or elongation ...
Dan Li +5 more
doaj +1 more source
Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives [PDF]
Nitrogen-based tetracyclic ortho-quinones (naphtho[1'2':4.5]imidazo[1,2-a]pyridine-5,6-diones, NPDOs) and their nitro-substituted derivatives (nitro-(P)NPDOs) were obtained by condensation of substituted 2,3-dichloro- 1,4-naphthoquinones with 2-amino ...
Anusevičius, Žilvinas +7 more
core +1 more source
Portable multimodal sensing system for screening of diabetes mellitus from human urine
A compact multimodal sensing device was developed for the simultaneous detection of glucose and acetone from urine samples. Combining electrochemical and gas sensors, the device demonstrates reliable performance within clinically relevant ranges. This portable system offers a holistic metabolic assessment, supporting early screening of diabetes and ...
Mario Soto Martinez +5 more
wiley +1 more source
The role of DJ-1 in enhancing mitochondrial quality control [PDF]
Thesis (M.A.)--Boston UniversityDJ-1 is a cytosolic sensor for oxidative damage which acts on the Mitochondria. It works to curb the negative effects of high membrane potential in mitochondria, but the mechanism of action is still uncertain.
Lingiah, Krishna Anand
core +1 more source
Parkinson's disease: autoimmunity and neuroinflammation [PDF]
Parkinson's disease is a neurodegenerative disease that causes the death of dopaminergic neurons in the substantia nigra. The resulting dopamine deficiency in the basal ganglia leads to a movement disorder that is characterized by classical parkinsonian ...
CINIGLIO APPIANI, MARIO +9 more
core +1 more source

