Results 1 to 10 of about 140,903 (359)

Quinoline-Based Molecules Targeting c-Met, EGF, and VEGF Receptors and the Proteins Involved in Related Carcinogenic Pathways

open access: yesMolecules, 2020
The quinoline ring system has long been known as a versatile nucleus in the design and synthesis of biologically active compounds. Currently, more than one hundred quinoline compounds have been approved in therapy as antimicrobial, local anaesthetic ...
Annamaria Martorana   +2 more
doaj   +2 more sources

Hydrogen-Bonding Interactions in Luminescent Quinoline-Triazoles with Dominant 1D Crystals

open access: yesMolecules, 2017
Quinoline-triazoles 2-((4-(diethoxymethyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (1), 2-((4-(m-tolyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (2) and 2-((4-(p-tolyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (3) have been prepared with CuAAC click reactions
Shi-Qiang Bai   +2 more
doaj   +1 more source

Carbon-13 n.m.r. investigation on the nitrogen methylation of the mono- and diazanaphthalenes [PDF]

open access: yes, 1977
The 13C n.m.r. spectra of the N-methylated mono- and diazanaphthalenes have been recorded and analysed. It has been shown that N-methylation as well as N-protonation in cinnoline occur predominantly at the -nitrogen atom.
Ham, Dirk M.W. van den   +2 more
core   +2 more sources

Quinoline-8-sulfonamide [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
In the title compound, C(9)H(8)N(2)O(2)S, the sulfamoyl NH(2) group is involved in intra-molecular N-H⋯N and inter-molecular N-H⋯O hydrogen bonding. In the crystal, molecules are linked via pairs of N-H⋯O hydrogen bonds, forming inversion dimers, which are further associated through π-π stacking inter-actions between the quinoline benzene rings ...
Marciniec, Krzysztof   +3 more
openaire   +2 more sources

Synthesis and in-vitro studies of some new quinoline 1,3,4-thiadiazolo pyrimidin derivatives

open access: yesBulletin of the Chemical Society of Ethiopia, 2017
A series of eight new quinoline associated 1,3,4-thiadiazolo pyrimidin derivatives (5a-h) have been developed using 4-amino-8-fluoro-quinoline-3-carboxylic acid ethyl ester (1) as raw material and by involving 8-fluoro-4-methylsulfanylthiocarbonylamino ...
K. K. Valluri,   +4 more
doaj   +1 more source

Diazanaphthalenes: A 13C NMR investigation on the site of protonation and pKa values [PDF]

open access: yes, 1976
The pH dependence of the 13C chemical shifts (δ) of the diazanaphthalenes has been recorded. From this dependence the pKa values have been determined using the Henderson-Hasselbach equation.
Meer, Douwe van der   +2 more
core   +2 more sources

A review on quinoline hydrazone derivatives as a new class of potent antitubercular and anticancer agents

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2017
Tuberculosis (TB) and Cancer remains a global public health problem in recent years. There is an urgent need for the screening of new bioactive molecules with new targets and with a different mechanism of action.
Mustapha C. Mandewale   +4 more
doaj   +1 more source

Benzimidazole-functionalized fluorescent probe for rapid detection of 2,4,6-trinitrophenol and Ag+ in semiaqueous medium [PDF]

open access: yesJournal of the Serbian Chemical Society, 2021
In this study, a simple fluorescent chemosensor with good fluorescence properties was synthesized, and was used to develop a sensitive and selective sensor, for the determination of 2,4,6-trinitrophenol (TNP) and Ag+ in THF/H2O medium, based on the ...
Wang Bin   +4 more
doaj   +1 more source

How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones. [PDF]

open access: yes, 2014
The origin of selectivity in the α-fluorination of cyclic ketones catalyzed by cinchona alkaloid-derived primary amines is determined with density functional calculations.
Houk, KN, Lam, Yu-hong
core   +2 more sources

Synthesis, Electrochemical and Spectroscopic Characterization of Selected Quinolinecarbaldehydes and Their Schiff Base Derivatives

open access: yesMolecules, 2020
A new approach to the synthesis of selected quinolinecarbaldehydes with carbonyl groups located at C5 and/or in C7 positions is presented in this paper in conjunction with spectroscopic characterization of the products.
Jakub Wantulok   +7 more
doaj   +1 more source

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