Results 101 to 110 of about 140,903 (359)

A Second Crystal Polymorph of Anilinium Picrate [PDF]

, 2004
The crystal structure of a second monoclinic polymorph of anilinium picrate shows a three-dimensional hydrogen-bonded polymer with strong primary interspecies interactions involving the proximal phenolate and adjacent nitro group O-atom acceptors and ...
Healy, Peter, Smith, Graham, Wermuth, Urs   +2 more
core   +2 more sources

Structural modifications of quinoline-based antimalarial agents: Recent developments

Journal of Pharmacy and Bioallied Sciences, 2010
Antimalarial drugs constitute a major part of antiprotozoal drugs and have been in practice for a long time. Antimalarial agents generally belong to the class of quinoline which acts by interfering with heme metabolism. The recent increase in development
Sandhya Bawa, Suresh Kumar, Sushma Drabu, Rajiv Kumar   +3 more
doaj   +1 more source

Perfluoro effect in the photoelectron spectra of quinoline and isoquinoline [PDF]

, 1972
The high-resolution He 584Aophotoelectron spectra of heptafluoroquinoline and heptafluoroisoquinoline are compared with those of the parent compounds. Shifts in π ionisation potentials, due to the fluorine substitution, can be described with an inductive
Ham, D.M.W. van den, Meer, D. van der
core   +3 more sources

QUINOLINE DERIVATIVES. PART IV.

, 1937
In view of the fact that glyoxatinoquinolines of Narang and Räy have the requisite antiseptic properties against paramaecia, benziminazolyIquinoline derivatives, which are expected to possess antimalarial properties, have been ...
openaire   +1 more source

Intermolecular Enantioselective Nickel‐Catalyzed Arylation of Un‐Activated C(sp3)─H Bond

Angewandte Chemie International Edition, EarlyView.
Ni: a new solution for asymmetric C(sp3)─H activation. The stereoselective synthesis of all‐carbon quaternary stereogenic centres is achieved via enantioselective C(sp3)─H arylation using a Ni‐BINOL‐derived catalyst. Rational catalytic cycle design uncovers a new reaction pathway that can efficiently induce chiral information during the stereoselective
Erwan Brunard, Fengjie Huang, Àlex Díaz‐Jiménez, Sofiya Kostiukovska, Joanna Wencel‐Delord   +4 more
wiley   +1 more source

Syntheses and crystal structures of a new pyrazine dicarboxamide ligand, N2,N3-bis(quinolin-8-yl)pyrazine-2,3-dicarboxamide, and of a copper perchlorate binuclear complex

Acta Crystallographica Section E: Crystallographic Communications, 2020
The title pyrazine dicarboxamide ligand, N2,N3-bis(quinolin-8-yl)pyrazine-2,3-dicarboxamide (H2L1), C24H16N6O2, has a twisted conformation with the outer quinoline groups being inclined to the central pyrazine ring by 9.00 (6) and 78.67 (5)°, and by 79 ...
Dilovan S. Cati, Helen Stoeckli-Evans
doaj   +1 more source

Pursing Quinoline-8-Sulfonamide derivatives for the identification of potent NPPs inhibitors: In silico molecular docking, molecular dynamics simulations and density field theory (DFT) studies

Results in Chemistry
Nucleotide pyrophosphatase/phosphodiesterase (NPP) enzymes belong to a broad category of ectonucleotidase enzymes. These NPPs are responsible for hydrolysis of extracellular nucleotides (ATP to AMP) and are therefore important regulators in the ...
Jamshed Iqbal, Talha Islam, Mariya al-Rashida, Abdul Hameed, Taseer Iftikhar, Julie Pelletier, Jean Sévigny, Salman Alrokayan, Maria Maqbool, Khurshid Ayub, Tajamul Hussain   +10 more
doaj   +1 more source

Crystal structure of bis(2,2′-bipyridine)[N′-(quinolin-2-ylmethylidene)pyridine-2-carbohydrazide]ruthenium(II) bis(tetrafluoridoborate) dichloromethane trisolvate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title compound, [Ru(C10H8N2)2(C16H12N4O)](BF4)2·3CH2Cl2, crystallizes with one complex dication, two BF4− counter-anions and three dichloromethane solvent molecules in the asymmetric unit.
Asami Mori, Takayoshi Suzuki, Kiyohiko Nakajima   +2 more
doaj   +1 more source

Rapid and Efficient Microwave‐Assisted Friedländer Quinoline Synthesis

ChemistryOpen, 2020
A microwave‐based methodology facilitates reaction of 2‐aminophenylketones with cyclic ketones to form a quinoline scaffold. Syntheses of amido‐ and amino‐linked 17β‐hydroxysteroid dehydrogenase type 3 inhibitors with a benzophenone‐linked motif were ...
Dr. Helen V. Bailey, Dr. Mary F. Mahon, Dr. Nigel Vicker, Prof. Barry V. L. Potter   +3 more
doaj   +1 more source

New Quinoline Kinase Inhibitors With Good Selectivity for NAK Kinases and Anti-Tumor Activity Against Ewing Sarcoma. [PDF]

Arch Pharm (Weinheim)
Focusing on the discovery of new therapeutics for childhood cancer, novel quinoline derivatives were synthesized and demonstrated activity against Ewing sarcoma. A target search was performed against a panel of kinases, and the compounds showed selectivity for the NAK family, mainly GAK, which was confirmed by enzyme kinetic assays.
Gentz CB, Fernandes THM, Lopes MS, Elson L, Krämer A, Souza LR, Fortes IS, Pinto GS, Martins MCS, Lima HB, Santiago ADS, Gregianin LJ, Massirer KB, Bengtson MH, Roesler R, Knapp S, Laufer SA, Andrade SF.   +17 more
europepmc   +2 more sources