Results 11 to 20 of about 35,351 (202)

Synthesis of antioxidant and antimicrobial bioactive compounds based on the quinoline-hydrazone and benzimidazole structure

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2023
Quinoline and its derivatives are known to have various biological activities such as antibacterial and antioxidant. Therefore, this study aims to synthesize quinoline moiety from isatin and ethyl acetoacetate by Pfitzinger reaction under acidic ...
Antonius Herry Cahyana   +2 more
doaj   +1 more source

Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides.

open access: yesPLoS Biology, 2009
Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of autoimmune/inflammatory diseases in humans.
Per Björk   +8 more
doaj   +1 more source

Benzimidazole-functionalized fluorescent probe for rapid detection of 2,4,6-trinitrophenol and Ag+ in semiaqueous medium [PDF]

open access: yesJournal of the Serbian Chemical Society, 2021
In this study, a simple fluorescent chemosensor with good fluorescence properties was synthesized, and was used to develop a sensitive and selective sensor, for the determination of 2,4,6-trinitrophenol (TNP) and Ag+ in THF/H2O medium, based on the ...
Wang Bin   +4 more
doaj   +1 more source

Quinolin-3-amine [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
In the crystal structur of the achiral title compound, C(9)H(8)N(2), N-H⋯N hydrogen bonds connect the mol-ecules into zigzag chains in [100]. Weak inter-molecular N-H⋯π inter-actions further consolidate the crystal packing.
Islor, Arun M.   +5 more
openaire   +2 more sources

Quinoline-2-carbaldehyde [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2011
The title compound, C(10)H(7)NO, crystallizes with two almost planar mol-ecules (A and B) in the asymmetric unit (r.m.s. deviations = 0.018 and 0.020 Å). In the crystal, the A mol-ecules are linked by weak C-H⋯O inter-actions, thereby generating C(9) [001] chains. The B mol-ecules do not exhibit any directional bonding inter-actions.
Martin O. Onani, William M. Motswainyana
openaire   +3 more sources

SYNTHESIS OF CERTAIN NOVEL PYRIDOTHIOPYRANOQUINOLINES AS POTENTIAL ANTICANCER AGENTS

open access: yesZagazig Journal of Pharmaceutical Sciences, 2006
A series of ethyl 2-substituted aminopyrido [3',2': 5,6] thiopyrano [ 4,3,2-de] quinoline-1-carboxylate (VII)i-viii was obtained by reacting ethyl2-chloropyrido[3',2':5,6] thiopyrano [4,3,2-de] quinoline-1-carboxylate (VIa) with certain aromatic amines ...
Khaled El-Shemy   +4 more
doaj   +1 more source

Quinoline-8-sulfonamide [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
In the title compound, C(9)H(8)N(2)O(2)S, the sulfamoyl NH(2) group is involved in intra-molecular N-H⋯N and inter-molecular N-H⋯O hydrogen bonding. In the crystal, molecules are linked via pairs of N-H⋯O hydrogen bonds, forming inversion dimers, which are further associated through π-π stacking inter-actions between the quinoline benzene rings ...
Marciniec, Krzysztof   +3 more
openaire   +2 more sources

Hydrogen-Bonding Interactions in Luminescent Quinoline-Triazoles with Dominant 1D Crystals

open access: yesMolecules, 2017
Quinoline-triazoles 2-((4-(diethoxymethyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (1), 2-((4-(m-tolyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (2) and 2-((4-(p-tolyl)-1H-1,2,3-triazol-1-yl)methyl)quinoline (3) have been prepared with CuAAC click reactions
Shi-Qiang Bai   +2 more
doaj   +1 more source

A review on quinoline hydrazone derivatives as a new class of potent antitubercular and anticancer agents

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2017
Tuberculosis (TB) and Cancer remains a global public health problem in recent years. There is an urgent need for the screening of new bioactive molecules with new targets and with a different mechanism of action.
Mustapha C. Mandewale   +4 more
doaj   +1 more source

Quinoline-Based Molecules Targeting c-Met, EGF, and VEGF Receptors and the Proteins Involved in Related Carcinogenic Pathways

open access: yesMolecules, 2020
The quinoline ring system has long been known as a versatile nucleus in the design and synthesis of biologically active compounds. Currently, more than one hundred quinoline compounds have been approved in therapy as antimicrobial, local anaesthetic ...
Annamaria Martorana   +2 more
doaj   +1 more source

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