Results 31 to 40 of about 3,612 (183)

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

Advanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai, Jiaqi Wang, Yu Liu, Guanda Jiao, Yuheng Gu, Yang Liu, Shengyu Fu, Xing Fan, Jialin Li, Ziang Guo, Kam Tong Leung, Lipeng Zhu, Qi Zhao   +12 more
wiley   +1 more source

Nanoimprinted DMD Electrodes Enabling Bidirectional Viewing OLEDs With Quasi Lambertian Emission

Advanced Science, EarlyView.
We present a dual‐approach strategy for high‐performance bidirectional‐viewing OLEDs, combining enhanced cavity resonance with a nanoimprinted dielectric/metal/dielectric (DMD) electrode. This bidirectional viewing OLED presents an 89.7% enhanced electrode transmittance, a balanced bidirectional emission ratio with 67.3% total brightness increase, as ...
Ningning Song, Ningning Liang, Xinghao Guo, Ruixiang Chen, Xia Xin, Yiming Chen, Ruiqi Tian, Tianrui Zhai   +7 more
wiley   +1 more source

[EMIM]AlCl4-ionic liquid catalyzed mechanochemically assisted green approach towards the synthesis of quinoxaline, 6H-indolo[2,3-b]quinoxaline and benzimidazole derivatives

Results in Chemistry
In the presented work, a convenient and effective methodology for the synthesis of quinoxaline, 6H-indolo[2,3-b]quinoxaline and benzimidazole derivatives has been developed.
Shafaque M. Shaikh, Gulafshan M. Ansari, Zobia Z. Karbari, Aditi A. Babre, Vikas V. Borge, Vikas M. Bangade, Damodara N. Kommi, Bhushan B. Popatkar   +7 more
doaj   +1 more source

Synthesis of pyrimido[1,6-a]quinoxalines via intermolecular trapping of thermally generated acyl(quinoxalin-2-yl)ketenes by Schiff bases

Beilstein Journal of Organic Chemistry, 2018
Acyl(quinoxalin-2-yl)ketenes generated by thermal decarbonylation of 3-acylpyrrolo[1,2-a]quinoxaline-1,2,4(5H)-triones react regioselectively with Schiff bases under solvent-free conditions to form pyrimido[1,6-a]quinoxaline derivatives in good yields.
Svetlana O. Kasatkina, Ekaterina E. Stepanova, Maksim V. Dmitriev, Ivan G. Mokrushin, Andrey N. Maslivets   +4 more
doaj   +1 more source

A Reliable Strategy to Unravel the Structure and Composition of Semiconducting Conjugated Donor‐Acceptor Block Copolymers

Advanced Science, EarlyView.
This work proposes a reliable strategy to elucidate the structure and composition of conjugated donor‐acceptor block copolymers. The method, based on NMR analysis, allows to extract key structural information such as the number of heterojunctions (NoH) and the number of blocks (NoB) of the copolymers.
Antoine Curé, Pierre‐Alain Bayle, Lucie Rivet, Yann Kervella, Renaud Demadrille, Cyril Aumaître   +5 more
wiley   +1 more source

Novel Derivatives of Quinoxaline-2-carboxylic Acid 1,4-Dioxides as Antimycobacterial Agents: Mechanistic Studies and Therapeutic Potential

Pharmaceuticals, 2023
The World Health Organization (WHO) reports that tuberculosis (TB) is one of the top 10 leading causes of global mortality. The increasing incidence of multidrug-resistant TB highlights the urgent need for an intensified quest to discover innovative anti-
Svetlana G. Frolova, Aleksey A. Vatlin, Dmitry A. Maslov, Buhari Yusuf, Galina I. Buravchenko, Olga B. Bekker, Ksenia M. Klimina, Svetlana V. Smirnova, Lidia M. Shnakhova, Irina K. Malyants, Arseniy I. Lashkin, Xirong Tian, Md Shah Alam, George V. Zatonsky, Tianyu Zhang, Andrey E. Shchekotikhin, Valery N. Danilenko   +16 more
doaj   +1 more source

Reinforcement of Cathode Interface Using a Dipolar Small Molecule for Enhancing Operational Stability of Perovskite Solar Cells

Advanced Science, EarlyView.
We report a high‐dipole interlayer, MQPPO, that simultaneously improves efficiency and stability in perovskite solar cells. Its strong interfacial dipole enhances photovoltaic performance, while its uniform coverage and strong interaction with Ag effectively suppress AgI formation, ensuring long‐term stability under moisture and thermal stress.
Dong Hyun Lee, Seok Woo Lee, Min Jun Choi, Ramesh Kumar Chitumalla, Sang Eun Yoon, Gyeong G. Jeon, Juan Anthony Prayogo, Dong Won Kim, Joonkyung Jang, Jinhee Heo, Dong Wook Chang, Jong H. Kim   +11 more
wiley   +1 more source

Enhanced Energy Transfer from a Metal–Organic Framework to a Highly Confined Organic Phosphorescent Dye

Advanced Science, EarlyView.
A phosphorescent dye was designed to fit in a hand‐to‐glove fashion into the 1D‐pore channels of MIL‐68(In). We synthesized MIL‐68(In) as powder and thin films, loaded the dye into the pores with controlled packing, and found that the phosphorescence and quantum yield are enhanced.
Bahram Hosseini Monjezi, Thomas Kasper, Gloria Hong, Changfeng Si, Robert Oestreich, Oliver Weingart, Peter G. Weidler, Christof Wöll, Eli Zysman‐Colman, Christoph Janiak, Stefan Bräse, Klaus Müller‐Buschbaum, Alexander Knebel   +12 more
wiley   +1 more source

Quinoxaline derivatives as new inhibitors of coxsackievirus B5 [PDF]

European Journal of Medicinal Chemistry, 2018
Enteroviruses are among the most common and important human pathogens for which there are no specific antiviral agents approved by the US Food and Drug Administration so far. Particularly, coxsackievirus infections have a worldwide distribution and can cause many important diseases. We here report the synthesis of new 14 quinoxaline derivatives and the
Carta, Antonio, Sanna, Giuseppina, Briguglio, Irene, Madeddu, Silvia, Vitale, Gabriella, Piras, Sandra, Corona, Paola, Peana, Alessandra Tiziana, Laurini, Erik, Fermeglia, Maurizio, Pricl, Sabrina, Serra, Alessandra, Carta, Elisa, Loddo, Roberta, Giliberti, Gabriele   +14 more
openaire   +3 more sources

Selective Charge Extraction Allows Fast Photomultiplication and Imaging in Rigid and Ultra‐Flexible SWIR Organic Photodiodes

Advanced Energy Materials, EarlyView.
SWIR donor polymer TQ‐3T allows photomultiplication in OPD in 1:1 ratio with NFA Y6, achieving EQEs > 1100% at ‐10 V. Microseconds response times are retained, amongst the lowest for photomultiplication. As proof of concept, we demonstrate ultrathin and flexible PM‐OPDs based on our TQ‐3T:Y6 as a flexible pulse oximeter as well as a conformable image ...
Matilde Brunetta, Zhuoran Qiao, Davide Nodari, Kosei Sasaki, Francesco Furlan, Martina Rimmele, Hongki Kim, Hongting Chen, Yusaku Tagawa, Adam Marsh, Rushil Vasant, Sang Do, Xabier Rodríguez‐Martínez, Anirudh Sharma, Christos L. Chochos, Jaime Martin, Martin Heeney, Koen Vandewal, Derya Baran, Thuc‐Quyen Nguyen, Bob C. Schroeder, Takao Someya, Tomoyuki Yokota, Nicola Gasparini   +23 more
wiley   +1 more source