Results 21 to 30 of about 6,285 (179)

Cerenkov Luminescence Imaging in the Development and Production of Radiopharmaceuticals

Frontiers in Physics, 2021
Over the past several years there has been an explosion of interest in exploiting Cerenkov radiation to enable in vivo and intraoperative optical imaging of subjects injected with trace amounts of radiopharmaceuticals.
R. Michael van Dam, R. Michael van Dam, Arion F. Chatziioannou, Arion F. Chatziioannou   +3 more
doaj   +1 more source

Synthesis and Biological Evaluation of a New Acyclic Pyrimidine Derivative as a Probe for Imaging Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression

Molecules, 2013
With the idea of finding a more selective radiotracer for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) gene expression by means of positron emission tomography (PET), a novel [18F]fluorine radiolabeled pyrimidine with 4-hydroxy-3 ...
Simon M. Ametamey, Silvana Raić-Malić, Stjepko Čermak, Roger Slavik, Adrienne Müller, Thomas Betzel, Andrijana Meščić   +6 more
doaj   +1 more source

Synthesis of No-Carrier-Added 4-[18F]Fluorophenol from 4-Benzyloxyphenyl-(2-thienyl)iodonium Bromide

Molecules, 2011
4-[18F]Fluorophenol is a versatile synthon for the synthesis of more complex radiopharmaceuticals bearing a 4-[18F]fluorophenoxy moiety. In order to prepare 4-[18F]fluorophenol in no-carrier-added (n.c.a.) form only a nucleophilic labelling method ...
Tobias L. Ross, Johannes Ermert, Heinz H. Coenen   +2 more
doaj   +1 more source

Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA

EJNMMI Radiopharmacy and Chemistry, 2021
The neurotracer 6-[18F] FDOPA has been, for many years, a powerful tool in PET imaging of neuropsychiatric diseases, movement disorders and brain malignancies.
Ângela C. B. Neves, Ivanna Hrynchak, Inês Fonseca, Vítor H. P. Alves, Mariette M. Pereira, Amílcar Falcão, Antero J. Abrunhosa   +6 more
doaj   +1 more source

Microliter-scale reaction arrays for economical high-throughput experimentation in radiochemistry

Scientific Reports, 2022
The increasing number of positron-emission tomography (PET) tracers being developed to aid drug development and create new diagnostics has led to an increased need for radiosynthesis development and optimization.
Alejandra Rios, Travis S. Holloway, Philip H. Chao, Christian De Caro, Chelsea C. Okoro, R. Michael van Dam   +5 more
doaj   +1 more source

Gamma Radiosynthesis of Colloidal Silver Nanoparticles Stabilized in ι-Carrageenan Under Atmospheric Gases: A Surface Plasmon Resonance Based Study

Atom Indonesia, 2021
ι-Carrageenan is a biodegradable and biocompatible biomaterial which potentially stabilizes colloidal silver nanoparticles (AgNPs). The present study explored gamma radiosynthesis of AgNPs at varied concentration of ι-carrageenan solutions.
D. P. Perkasa, M. Y. Yunus, Y. Warastuti, B. Abbas   +3 more
doaj   +1 more source

An Efficient and Practical Radiosynthesis of [¹¹C]Temozolomide

, 2016
An Efficient and Practical Radiosynthesis of [11C ...
Ramesh Neelamegam (1309647), Stephen M. Carlin (303025), Jacob M. Hooker (388460), Christian K. Moseley (388458)   +3 more
core   +2 more sources

A closer look at the synthesis of 2-[18F]fluoroethyl tosylate to minimize the formation of volatile side-products

EJNMMI Radiopharmacy and Chemistry, 2022
Background 2-[18F]Fluoroethyltosylate ([18F]FEtOTs) is a well-known 18F-fluoroalkylating agent widely used to synthesize radiotracers for positron emission tomography.
Martha Sahylí Ortega Pijeira, Sofia Nascimento dos Santos, Yasniel Babi Araujo, André Luis Lapolli, Marcio Nardelli Wandermuren, Zalua Rodríguez Riera, Ivone Carvalho, Philip H. Elsinga, Emerson Soares Bernardes   +8 more
doaj   +1 more source

[¹⁸F]AB5186 radiosynthesis.

, 2019
[18F]AB5186 radiosynthesis.
Gillian A. Gray (6786209), Sally L. Pimlott (1366506), Christophe Lucatelli (3033765), Lewis Williams (5811791), Mark G. MacAskill (6786194), David E. Newby (411328), Andrew Sutherland (1298325), Timaeus E. F. Morgan (6786200), Carlos José Alcaide-Corral (6786203), Adriana A. S. Tavares (6786212), Tashfeen Walton (6786197), Marc R. Dweck (6786206)   +11 more
core   +1 more source

Radiosynthesis of 2-[¹⁸F]F-PZA.

, 2017
Radiosynthesis of 2-[18F]F-PZA.
Peter Smith-Jones (1339275), Alvaro A. Ordonez (2880218), Fereidoon Daryaee (2566246), Sanjay K. Jain (318001), Hui Wang (30400), Yong S. Chang (3712957), Kayla R. Gogarty (3712960), Lauren E. Bambarger (3712963), Zhuo Zhang (72795), Peter J. Tonge (262325)   +9 more
core   +1 more source