Results 31 to 40 of about 6,285 (179)

Scheme of the radiosynthesis of [¹¹C]MGLU.

, 2014
Scheme of the radiosynthesis of [11C]MGLU.
Hongliang Wang (440441), Kan Du (544682), Baoguo Yao (544685), Linquan Zang (216085), Tingting Huang (496866), Ganghua Tang (544683), Xiang Liang (363933), Kongzhen Hu (544681), Shaobo Yao (544684)   +8 more
core   +1 more source

Multicenter Experience with Good Manufacturing Practice Production of [¹¹C]PiB for Amyloid Positron Emission Tomography Imaging

Pharmaceuticals
Alzheimer’s disease (AD) is a neurodegenerative disorder with increasing global prevalence and accounts for over half of all dementia cases. Early diagnosis is paramount for not only the management of the disease, but also for the development of new AD ...
Anders Bruhn Arndal Andersen, Szabolcs Lehel, Ebbe Klit Grove, Niels Langkjaer, Dan Fuglø, Tri Hien Viet Huynh   +5 more
doaj   +1 more source

Spatiotemporal Tau Accumulation and its Clinical Impact on Progressive Supranuclear Palsy: Longitudinal Florzolotau (18F) Positron Emission Tomography

Movement Disorders, EarlyView.
Abstract Background Florzolotau (18F) positron emission tomography (florzolotau PET) enables high‐contrast in vivo detection of four‐repeat tau pathology in progressive supranuclear palsy (PSP), but whether longitudinal tau imaging reflects disease progression remains unclear.
Yoshikazu Chishiki, Kenji Tagai, Yuko Kataoka, Ryoji Goto, Kenta Osawa, Asaka Oyama, Hideki Matsumoto, Masanori Ichihashi, Yuki Momota, Tetsuji Kamada, Chie Seki, Kiwamu Matsuoka, Kosei Hirata, Shin Kurose, Sho Moriguchi, Yuki Komatsu, Hideo Kato, Yasuharu Yamamoto, Yoshikazu Nakano, Shigeki Hirano, Hitoshi Shinotoh, Hitoshi Shimada, Tokahiko Tokuda, Kazunori Kawamura, Ming‐Rong Zhang, Keisuke Takahata, Makoto Higuchi, Hironobu Endo   +27 more
wiley   +1 more source

Schematic of [¹⁸F]AlF-NOTA-C6 radiosynthesis.

, 2015
Schematic of [18F]AlF-NOTA-C6 radiosynthesis.
Donghui Pan (822629), Hongdie Jiang (822631), Tao Wang (12008), Changjing Zuo (822632), Yuping Xu (727176), Dazhi Zhang (702709), Chao Cheng (11274), Hongrui Liu (751989), Lizhen Wang (340620), Fei Chen (13690), Qinghua Liu (64392), Min Yang (146229), Anyu Zhang (822630), Runlin Yang (785398)   +13 more
core   +1 more source

Advancements in Microfluidic Cassette-Based iMiDEV™ Technology for Production of L-[¹¹C]Methionine and [¹¹C]Choline

Pharmaceuticals
Microfluidic technology is a highly efficient technique used in positron emission tomography (PET) radiochemical synthesis. This approach enables the precise control of reactant flows and reaction conditions, leading to improved yields and reduced ...
Hemantha Mallapura, Laurent Tanguy, Samin Mahfuz, Lovisa Bylund, Bengt Långström, Christer Halldin, Sangram Nag   +6 more
doaj   +1 more source

Fully automated 18F-fluorination of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) for indirect labelling of nanobodies

Scientific Reports, 2022
N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB), a widely used labeling agent to introduce the 4-[18F]fluorobenzoyl-prosthetic group, is normally obtained in three consecutive steps from [18F]fluoride ion. Here, we describe an efficient one-step labeling
Surasa Nagachinta, Paolo Novelli, Yoann Joyard, Nicolas Maindron, Patrick Riss, Sylvestre Dammicco   +5 more
doaj   +1 more source

Scheme 2. Radiosynthesis of iodinated pyridyl benzofuran derivatives.

, 2013
Scheme 2. Radiosynthesis of iodinated pyridyl benzofuran derivatives.
Kenji Matsumura (458367), Yoko Okamoto (350661), Hiroyuki Kimura (261126), Hiroyuki Watanabe (312793), Yan Cheng (149222), Masashi Yoshimura (328061), Masafumi Ihara (302200), Masahiro Ono (106488), Shimpei Iikuni (458368), Ryosuke Takahashi (108123), Hideo Saji (458369)   +10 more
core   +1 more source

[18F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model

Molecules, 2018
[18F]FEPPA is a specific ligand for the translocator protein of 18 kDa (TSPO) used as a positron emission tomography (PET) biomarker for glial activation and neuroinflammation.
Nicolas Vignal, Salvatore Cisternino, Nathalie Rizzo-Padoin, Carine San, Fortune Hontonnou, Thibaut Gelé, Xavier Declèves, Laure Sarda-Mantel, Benoît Hosten   +8 more
doaj   +1 more source

Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor. [PDF]

PLoS ONE, 2017
New radiochemistry techniques can yield novel PET tracers for COX-2 and address the shortcomings in in vivo stability and specificity, which have held back clinical translation of tracers to image COX-2 expression. Current techniques limit radiosynthesis
Artem Lebedev, Jing Jiao, Jason Lee, Fan Yang, Nathanael Allison, Harvey Herschman, Saman Sadeghi   +6 more
doaj   +1 more source

Scheme of the radiosynthesis of [¹⁸F]FPGLU.

, 2014
Scheme of the radiosynthesis of [18F]FPGLU.
Hongliang Wang (440441), Kan Du (544682), Baoguo Yao (544685), Linquan Zang (216085), Tingting Huang (496866), Ganghua Tang (544683), Xiang Liang (363933), Kongzhen Hu (544681), Shaobo Yao (544684)   +8 more
core   +1 more source