Results 31 to 40 of about 6,098 (221)
Angewandte Chemie, EarlyView.An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee +7 more
wiley +2 more sources
Cerenkov Luminescence Imaging in the Development and Production of Radiopharmaceuticals
Frontiers in Physics, 2021 Over the past several years there has been an explosion of interest in exploiting Cerenkov radiation to enable in vivo and intraoperative optical imaging of subjects injected with trace amounts of radiopharmaceuticals.
R. Michael van Dam +3 more
doaj +1 more source
Robust and Facile Automated Radiosynthesis of [18F]FSPG on the GE FASTlab [PDF]
, 2020 Purpose: (S)-4-(3-18F-Fluoropropyl)-ʟ-Glutamic Acid ([18F]FSPG) is a radiolabeled non-natural amino acid that is used for positron emission tomography (PET) imaging of the glutamate/cystine antiporter, system xC-, whose expression is upregulated in many ...
Timothy, Witney +2 more
core +1 more source
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
EJNMMI Radiopharmacy and Chemistry, 2021 The neurotracer 6-[18F] FDOPA has been, for many years, a powerful tool in PET imaging of neuropsychiatric diseases, movement disorders and brain malignancies.
Ângela C. B. Neves +6 more
doaj +1 more source
Molecules, 2013 With the idea of finding a more selective radiotracer for imaging herpes simplex virus type 1 thymidine kinase (HSV1-tk) gene expression by means of positron emission tomography (PET), a novel [18F]fluorine radiolabeled pyrimidine with 4-hydroxy-3 ...
Simon M. Ametamey +6 more
doaj +1 more source
Synthesis of No-Carrier-Added 4-[18F]Fluorophenol from 4-Benzyloxyphenyl-(2-thienyl)iodonium Bromide
Molecules, 2011 4-[18F]Fluorophenol is a versatile synthon for the synthesis of more complex radiopharmaceuticals bearing a 4-[18F]fluorophenoxy moiety. In order to prepare 4-[18F]fluorophenol in no-carrier-added (n.c.a.) form only a nucleophilic labelling method ...
Tobias L. Ross +2 more
doaj +1 more source
Microliter-scale reaction arrays for economical high-throughput experimentation in radiochemistry
Scientific Reports, 2022 The increasing number of positron-emission tomography (PET) tracers being developed to aid drug development and create new diagnostics has led to an increased need for radiosynthesis development and optimization.
Alejandra Rios +5 more
doaj +1 more source
Atom Indonesia, 2021 ι-Carrageenan is a biodegradable and biocompatible biomaterial which potentially stabilizes colloidal silver nanoparticles (AgNPs). The present study explored gamma radiosynthesis of AgNPs at varied concentration of ι-carrageenan solutions.
D. P. Perkasa +3 more
doaj +1 more source
EJNMMI Radiopharmacy and Chemistry, 2022 Background 2-[18F]Fluoroethyltosylate ([18F]FEtOTs) is a well-known 18F-fluoroalkylating agent widely used to synthesize radiotracers for positron emission tomography.
Martha Sahylí Ortega Pijeira +8 more
doaj +1 more source
Radiosynthesis and reactivity of N-[11C]methyl carbamoylimidazole [PDF]
Journal of Radioanalytical and Nuclear Chemistry, 2018 N-Methyl carbamoylimidazole is a safe and practical alternative to methyl isocyanate for carbamoylation reactions. We have developed a new chemical route for its synthesis from methyl iodide and applied this to the synthesis of N-[11C]methyl carbamoylimidazole as a new [11C]synthon to radiolabel biomolecules for PET imaging research.
Kadirvel, Manikandan +3 more
openaire +4 more sources