Results 51 to 60 of about 6,098 (221)

Improvement of Radiosynthesis Yield of [11C]acetate [PDF]

, 2018
Purpose [11C] acetate has been proved useful in detecting the myocardial oxygen metabolism and various malignancies including prostate cancer, hepatocellular carcinoma, renal cell carcinoma and brain tumors.
박준영
core  

Scheme of the radiosynthesis of [¹¹C]MGLU.

, 2014
Scheme of the radiosynthesis of [11C]MGLU.
Hongliang Wang (440441), Kan Du (544682), Baoguo Yao (544685), Linquan Zang (216085), Tingting Huang (496866), Ganghua Tang (544683), Xiang Liang (363933), Kongzhen Hu (544681), Shaobo Yao (544684)   +8 more
core   +1 more source

Radiosynthesis and analysis of (S)-4-(3-[18F]fluoropropyl)-L-glutamic acid [PDF]

, 2023
Purpose: (S)-4-(3-[18F]Fluoropropyl)-L-glutamic acid ([18F]FSPG) is an L-glutamate derivative used as a PET biomarker to assess intracellular redox status in vivo through targeting of the cystine/glutamate antiporter protein, xc− transporter.
David Y. Lewis, Brown, Gavin, Soloviev, Dmitry, Dmitry Soloviev, Lewis, David Y., Gavin Brown   +5 more
core   +1 more source

[18F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model

Molecules, 2018
[18F]FEPPA is a specific ligand for the translocator protein of 18 kDa (TSPO) used as a positron emission tomography (PET) biomarker for glial activation and neuroinflammation.
Nicolas Vignal, Salvatore Cisternino, Nathalie Rizzo-Padoin, Carine San, Fortune Hontonnou, Thibaut Gelé, Xavier Declèves, Laure Sarda-Mantel, Benoît Hosten   +8 more
doaj   +1 more source

Radiochemistry on electrodes: Synthesis of an 18F-labelled and in vivo stable COX-2 inhibitor. [PDF]

PLoS ONE, 2017
New radiochemistry techniques can yield novel PET tracers for COX-2 and address the shortcomings in in vivo stability and specificity, which have held back clinical translation of tracers to image COX-2 expression. Current techniques limit radiosynthesis
Artem Lebedev, Jing Jiao, Jason Lee, Fan Yang, Nathanael Allison, Harvey Herschman, Saman Sadeghi   +6 more
doaj   +1 more source

Spatiotemporal Tau Accumulation and its Clinical Impact on Progressive Supranuclear Palsy: Longitudinal Florzolotau (18F) Positron Emission Tomography

Movement Disorders, EarlyView.
Abstract Background Florzolotau (18F) positron emission tomography (florzolotau PET) enables high‐contrast in vivo detection of four‐repeat tau pathology in progressive supranuclear palsy (PSP), but whether longitudinal tau imaging reflects disease progression remains unclear.
Yoshikazu Chishiki, Kenji Tagai, Yuko Kataoka, Ryoji Goto, Kenta Osawa, Asaka Oyama, Hideki Matsumoto, Masanori Ichihashi, Yuki Momota, Tetsuji Kamada, Chie Seki, Kiwamu Matsuoka, Kosei Hirata, Shin Kurose, Sho Moriguchi, Yuki Komatsu, Hideo Kato, Yasuharu Yamamoto, Yoshikazu Nakano, Shigeki Hirano, Hitoshi Shinotoh, Hitoshi Shimada, Tokahiko Tokuda, Kazunori Kawamura, Ming‐Rong Zhang, Keisuke Takahata, Makoto Higuchi, Hironobu Endo   +27 more
wiley   +1 more source

Schematic of [¹⁸F]AlF-NOTA-C6 radiosynthesis.

, 2015
Schematic of [18F]AlF-NOTA-C6 radiosynthesis.
Donghui Pan (822629), Hongdie Jiang (822631), Tao Wang (12008), Changjing Zuo (822632), Yuping Xu (727176), Dazhi Zhang (702709), Chao Cheng (11274), Hongrui Liu (751989), Lizhen Wang (340620), Fei Chen (13690), Qinghua Liu (64392), Min Yang (146229), Anyu Zhang (822630), Runlin Yang (785398)   +13 more
core   +1 more source

A Fully Automated Synthesis of 14-(R,S)-[¹⁸F]fluoro-6-thia-heptadecanoic Acid ([¹⁸F]FTHA) on the Elixys Radiosynthesizer

Pharmaceuticals
14-(R,S)-[18F]fluoro-6-thia-heptadecanoic acid ([18F]FTHA) is a radiocompound for imaging the fatty acid circulation by positron emission tomography.
Usevalad Ustsinau, Lukas Nics, Marcus Hacker, Cecile Philippe   +3 more
doaj   +1 more source

GMP‐compliant production, validation and dosimetry of clinical grade [18F]3‐(3‐fluoropropyl)‐2‐phenyl‐2,3‐dihydrobenzo[d]thiazole ([18F]FPBT) for oxidative stress PET imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non‐invasive detection remain limited. This study aimed to systematically validate a superoxide‐selective PET tracer, [18F]FPBT, for the early diagnosis and therapeutic monitoring of oxidative stress‐related conditions ...
Hua Zhang, Fangfang Sun, Chun Li, Xin Wang, Yuexuan Song, Lu Jiang, Paul Gape, Samantha Y. A. Terry, Shujun He, Ran Yan, Zhi Lu   +10 more
wiley   +1 more source

Scheme of the radiosynthesis of [¹⁸F]FPGLU.

, 2014
Scheme of the radiosynthesis of [18F]FPGLU.
Hongliang Wang (440441), Kan Du (544682), Baoguo Yao (544685), Linquan Zang (216085), Tingting Huang (496866), Ganghua Tang (544683), Xiang Liang (363933), Kongzhen Hu (544681), Shaobo Yao (544684)   +8 more
core   +1 more source