Results 61 to 70 of about 6,285 (179)
[18F]PSMA‐1007 PET–Based Recurrence Site Distribution and Predictors of Metastatic Disease in Patients With Biochemical Recurrence of Prostate Cancer
International Journal of Urology, Volume 33, Issue 8, August 2026.ABSTRACT Objectives
Prostate‐specific membrane antigen positron emission tomography (PSMA‐PET) is a sensitive imaging modality for detecting recurrent prostate cancer following definitive local therapy. However, evidence on 18F‐labeled PSMA tracers in Japanese patients with biochemical recurrence (BCR) remains limited.Koji Hatano, Tadashi Watabe, Takero Hirata, Masatoshi Konishi, Tomohiro Kanaki, Masaru Tani, Toshiki Oka, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Kazutoshi Fujita, Motohide Uemura, Frederik L. Giesel, Norio Nonomura +15 morewiley +1 more sourceRadiosynthesis of [11C]ITMM with conventional or ultra-high SA.
, 2015 Radiosynthesis of [11C]ITMM with conventional or ultra-high SA.Masanao Ogawa (136804), Kazunori Kawamura (136818), Ming-Rong Zhang (136828), Hidekatsu Wakizaka (416889), Akiko Hatori (136785), Masayuki Fujinaga (136798), Joji Yui (136787), Nobuki Nengaki (136810), Tomoyuki Ohya (755248), Lin Xie (136792), Tomoteru Yamasaki (136789), Yoko Ikoma (755249) +11 morecore +1 more sourceDevelopment of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators
Frontiers in ChemistryGallium-68-labeled FAPI-46 has recently been proposed as a novel positron emission tomography imaging probe to diagnose and monitor a wide variety of cancers.Louis-Paul Paty, Simon Degueldre, Claire Provost, Claire Provost, Camille Schmitt, Laura Trump, Laura Trump, Julien Fouque, Julien Fouque, Charles Vriamont, Frank Valla, Thibault Gendron, Olivier Madar, Olivier Madar +13 moredoaj +1 more sourceIdentification of Pyrazolidine‐3‐One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors
ChemMedChem, Volume 21, Issue 14, 29 July 2026.Following the discovery of oxadiazin‐5‐ones as partial inhibitors of the ATP synthase, we herein report the synthesis of a library of pyrazolidine‐3‐ones and pyrazol‐3‐ones, designed by reducing the six‐membered N–N heterocycles to five‐membered rings.Lisa Reichert, Aro Delparente, Ida R. Hipfinger, Lukas Reininger, Ana Pinto Castro, Daniel J. Hubin, Roger Schibli, Amy E. Fraley, Linjing Mu +8 morewiley +1 more sourceUnveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy
Alzheimer's &Dementia, Volume 22, Issue 7, July 2026. Abstract INTRODUCTION
A subset of Alzheimer's disease (AD) patients exhibits a procoagulant state that remains undiagnosed despite available treatments. We developed positron emission tomography (PET) strategies to in vivo detect cerebral microthrombi in TgCRND8 mice. METHODS
PET was performed with a fibrin‐binding probe (FBP) in TgCRND8 and wild‐type Carlos Ceron, Marta Casquero‐Veiga, Nicolás Lamanna‐Rama, Irene Fernández‐Nueda, Alberto Fernández‐Pena, Nancy Olazagoitia, Gorka Sobrino, Aitor Herraiz, María Isabel González, María Muñoz‐Hernando, Alejandro Ruperti‐Repilado, Eduardo Romero‐Sanz, Miguel Ángel Morcillo, Carlos Pérez‐Medina, Maria Angeles Moro, Gonzalo Villaverde, Jorge Rubio, Jose Fernandez‐Ferro, Manuel Desco, Fernando Herranz, Beatriz Salinas, Valentin Fuster, Marta Cortes‐Canteli +22 morewiley +1 more sourceRadiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated 18F-trifluoromethylation procedure
, 2018 Automated 18F-trifluoromethylation provided the first radiosynthesis of [18F]Trifluridine, which shows potential as a PET probe of drug mechanism of action.Chung, Y-L, Chiara Da Pieve, Da Pieve, C, Ciobota, DM, King, A, Turton, D, Gabriela Kramer-Marek, David Turton, Andreas Doepner, Daniela M. Ciobota, Graham Smith, Wong Te Fong, A-C, Kramer-Marek, G, Smith, G, Anne-Christine Wong Te Fong, Yuen-Li Chung, Alice King, Doepner, A +17 morecore +1 more sourceDevelopment and characterization of a novel TDP‐43 positron emission tomography tracer: [18F]JNJ‐TDP43‐1
Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.Abstract INTRODUCTION
Neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), limbic‐predominant age‐related TDP‐43 encephalopathy (LATE), and Alzheimer's disease (AD) are associated with TAR DNA‐binding protein 43 (TDP‐43) pathology.Chunfang A. Xia, Mani Salarian, Christopher J. Gartshore, Antonella Scaglione, Thomas Hayes, Shuanglong Liu, Hsiu‐Ming Tsai, Javier Echavarren, Jose Maria Cid, Alessandra Matzeu, A. Katrin Szardenings +10 morewiley +1 more sourceRadiosynthesis of 18F-FP-PEG2-β-Glu-RGD2.
, 2015 Radiosynthesis of 18F-FP-PEG2-β-Glu-RGD2.Hongliang Wang (440441), Caihua Tang (798924), Baoguo Yao (544685), Ganghua Tang (544683), Xiang Liang (363933), Shanzhen He (798925), Kongzhen Hu (544681), Xiaolan Tang (798922), Dahong Nie (798923), Shaobo Yao (544684) +9 morecore +1 more sourceSupplementary Figure S1 from A Clinical PET Imaging Tracer ([18F]DASA-23) to Monitor Pyruvate Kinase M2–Induced Glycolytic Reprogramming in Glioblastoma
, 2021 [18F]DASA-23 ...Tom Haywood (14942704), Mary Ellen I. Koran (15039035), Lewis Naya (15039026), Megan Phillips (15039032), Samantha T. Reyes (15039029), Eli Johnson (15039050), Monica Granucci (15039047), Geoffrey I. Warnock (9439259), Israt S. Alam (2298010), Michelle L. James (6619205), Mehdi Khalighi (15039062), Reena Thomas (8558853), Harsh Gandhi (15039041), Corinne Beinat (14942707), Kim Halbert (15039038), Andrei Iagaru (15033948), Irving Weissman (2616616), Tarik F. Massoud (15039065), Pauline Chu (4596154), Guido Davidzon (15039068), Joy Q. He (15039044), Lawrence D. Recht (14872434), Pablo Buccino (6986006), Surya Murty (408214), Bin Shen (143992), Seema Nagpal (15039071), Sanjiv Sam Gambhir (15039074), Chirag B. Patel (6293084), Jessa B. Castillo (11584261), Daniel Dan Liu (15039053), Rahul Sinha (156493), Jun Hyung Park (4371853), Donald E. Born (15039056), Melanie Hayden-Gephart (15039059), Nobuko Uchida (362419), Dawn Holley (3684490) +35 morecore +1 more source
