Results 81 to 90 of about 6,285 (179)

Optimized and Automated Radiosynthesis of [18F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography

Molecules, 2016
Reactive oxygen species (ROS) play important roles in cell signaling and homeostasis. However, an abnormally high level of ROS is toxic, and is implicated in a number of diseases.
Wenjie Zhang, Zhengxin Cai, Lin Li, Jim Ropchan, Keunpoong Lim, Nabil E. Boutagy, Jing Wu, John C. Stendahl, Wenhua Chu, Robert Gropler, Albert J. Sinusas, Chi Liu, Yiyun Huang   +12 more
doaj   +1 more source

In Vivo Imaging of the Innate Immune System in the Pancreas in New‐Onset and Long‐Standing Type 1 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4876-4883, June 2026.
ABSTRACT Objective Type 1 diabetes (T1D) is an autoimmune disease, but knowledge of immune cell infiltration in the human pancreas is limited due to the risks associated with pancreatic biopsies. This study aimed to evaluate the feasibility of imaging innate immune cells in vivo using positron emission tomography (PET).
Ebrahim Anvari, Hongchao Zhang, Henrik Hill, Nathalia Guarienti Missima, Per Liss, Irina Velikyan, Gunnar Antoni, Olle Korsgren, Daniel Espes, Olof Eriksson   +9 more
wiley   +1 more source

From [¹¹C]CO₂ to [¹¹C]amides: a rapid one-pot synthesis via the Mitsunobu reaction [PDF]

, 2017
Radiosynthesis of [11C]amides via the Mitsunobu reaction.
Dheere, A K Haji; id_orcid, C. Taddei, A. Runser, Taddei, C, Gee, A D, Bongarzone, S; id_orcid, S. Bongarzone, A. K. Haji Dheere, A. D. Gee, Runser, A   +9 more
core   +1 more source

Automated Radiosynthesis of [11C]UCB-J for Imaging Synpatic Density by PET [PDF]

, 2020
An automated radiosynthesis of carbon-11 PET radiotracer [11C]UCB-J for imaging the synaptic density biomarker synaptic vesicle glycoprotein SV2A was established using Synthra RNPlus synthesizer.

core   +3 more sources

Improved automated one-pot two-step radiosynthesis of (S)-[18F]FETrp, a radiotracer for PET imaging of indoleamine 2,3-dioxygenase 1 (IDO1)

EJNMMI Radiopharmacy and Chemistry
Background (S)-[18F]FETrp is a promising PET radiotracer for imaging IDO1 activity, one of the main enzymes involved in the tryptophan metabolism that plays a key role in several diseases including cancers.
Aurélie Maisonial-Besset, David Kryza, Klaus Kopka, Sophie Levesque, Emmanuel Moreau, Barbara Wenzel, Jean-Michel Chezal   +6 more
doaj   +1 more source

Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Ligand for in Vivo Imaging of the Adenosine A_2A Receptor System Using Positron Emission Tomography

, 2016
Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Ligand for in Vivo Imaging of the Adenosine A2A Receptor System Using Positron Emission ...
Barbara Cacciari (832354), Sergio Todde (3011961), Marzia Galli Kienle (3011958), Pasquale Simonelli (3011952), Katia Varani (289338), Mario Matarrese (2434324), Pier Giovanni Baraldi (1570153), Angela Monopoli (125880), Assunta Carpinelli (3011955), Ferruccio Fazio (2434306), Rosa Maria Moresco (2434318), Fulvio Magni (627391), Giampiero Spalluto (832355)   +12 more
core   +1 more source

Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats

Frontiers in Pharmacology
ObjectiveTo optimize the automated radiosynthesis of the purinergic ion channel receptor 7 (P2X7R) imaging agent 18F-JNJ64413739 and evaluate its potential for brain imaging in osteoporotic model rats.MethodsA more electron-deficient nitropyridine was ...
Yingtong Lu, Yan Cui, Lu Hou, Yuanfang Jiang, Jingjie Shang, Lu Wang, Hao Xu, Weijian Ye, Yang Qiu, Bin Guo   +9 more
doaj   +1 more source

Radiochemical yield of [¹⁸F]SFB by one-pot radiosynthesis under different water content conditions (data are the mean ± S.D., n = 3).

, 2016
Radiochemical yield of [18F]SFB by one-pot radiosynthesis under different water content conditions (data are the mean ± S.D., n = 3).
Ren Iwata (812734), Hiroyuki Kimura (261126), Yuji Kuge (458337), Kenji Arimitsu (180751), Masahiro Ono (106488), Hiroaki Nakanishi (2727712), Eiichi Ozeki (1765183), Hidekazu Saiki (3154818), Kenji Tomatsu (3154821), Hidekazu Kawashima (2259781), Hideo Saji (458369)   +10 more
core   +1 more source

NMR data FBz/FBn polyamines

, 2021
Files of NMR data for the different fluorobenz(o)ylated polyamines and radiosynthesis ...
Wodtke, Robert, Löser, Reik
core   +1 more source

Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer

Pharmaceuticals, 2017
Radiolabeled tracers targeting the prostate-specific membrane antigen (PSMA) have become important radiopharmaceuticals for the PET-imaging of prostate cancer.
Jens Cardinale, René Martin, Yvonne Remde, Martin Schäfer, Antje Hienzsch, Sandra Hübner, Anna-Maria Zerges, Heike Marx, Ronny Hesse, Klaus Weber, Rene Smits, Alexander Hoepping, Marco Müller, Oliver C. Neels, Klaus Kopka   +14 more
doaj   +1 more source